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Rynearson, Kevin D.
48  Ergebnisse:
Personensuche X
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1

γ‐Secretase Modulator BPN15606 Reduced Aβ42 and Aβ40 and Co..:

Chen, Xu‐Qiao ; Becker, Ann ; Albay, Ricardo...
Annals of Neurology.  96 (2024)  2 - p. 390-404 , 2024
Link: https://doi.org/10.1002/..
 
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2

Retromer Proteins Reduced in Down Syndrome and the Dp16 Mod..:

Chen, Xu‐Qiao ; Sawa, Mariko ; Becker, Ann...
Annals of Neurology.  94 (2023)  2 - p. 245-258 , 2023
Link: https://doi.org/10.1002/..
 
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3

Endotype reversal as a novel strategy for screening drugs t..:

Caldwell, Andrew B. ; Liu, Qing ; Zhang, Can...
Alzheimer's & Dementia.  18 (2022)  11 - p. 2117-2130 , 2022
Link: https://doi.org/10.1002/..
 
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4

Preclinical validation of a potent γ-secretase modulator fo..:

Rynearson, Kevin D. ; Ponnusamy, Moorthi ; Prikhodko, Olga...
Journal of Experimental Medicine.  218 (2021)  4 - p. , 2021
Link: https://doi.org/10.1084/..
 
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5

Molecular imaging of Alzheimer's disease–related gamma-secr..:

Xu, Yulong ; Wang, Changning ; Wey, Hsiao-Ying...
Journal of Experimental Medicine.  217 (2020)  12 - p. , 2020
Link: https://doi.org/10.1084/..
 
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6

Design and synthesis of novel methoxypyridine-derived gamma..:

Rynearson, Kevin D. ; Buckle, Ronald N. ; Herr, R. Jason...
Bioorganic & Medicinal Chemistry.  28 (2020)  22 - p. 115734 , 2020
Link: https://doi.org/10.1016/..
 
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7

γ-Secretase Partitioning into Lipid Bilayers Remodels Membr..:

Barros, Marilia ; Houlihan, William J. ; Paresi, Chelsea J....
Langmuir.  36 (2020)  23 - p. 6569-6579 , 2020
Link: https://doi.org/10.1021/..
 
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8

Cholesterol Metabolism Is a Druggable Axis that Independent..:

van der Kant, Rik ; Langness, Vanessa F. ; Herrera, Cheryl M....
Cell Stem Cell.  24 (2019)  3 - p. 363-375.e9 , 2019
Link: https://doi.org/10.1016/..
 
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9

Soluble Gamma-secretase Modulators Attenuate Alzheimer's β-..:

Raven, Frank ; Ward, Joseph F. ; Zoltowska, Katarzyna M....
EBioMedicine.  24 (2017)  - p. 93-101 , 2017
Link: https://doi.org/10.1016/..
 
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10

Design and synthesis of aminothiazole modulators of the gam..:

Rynearson, Kevin D. ; Buckle, Ronald N. ; Barnes, Keith D....
Bioorganic & Medicinal Chemistry Letters.  26 (2016)  16 - p. 3928-3937 , 2016
Link: https://doi.org/10.1016/..
 
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11

Nanopore-Based Conformational Analysis of a Viral RNA Drug ..:

Shasha, Carolyn ; Henley, Robert Y. ; Stoloff, Daniel H....
ACS Nano.  8 (2014)  6 - p. 6425-6430 , 2014
Link: https://doi.org/10.1021/..
 
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12

Soluble γ-Secretase Modulators Selectively Inhibit the Prod..:

Wagner, Steven L. ; Zhang, Can ; Cheng, Soan...
Biochemistry.  53 (2014)  4 - p. 702-713 , 2014
Link: https://doi.org/10.1021/..
 
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13

2-Aminobenzoxazole ligands of the hepatitis C virus interna..:

Rynearson, Kevin D. ; Charrette, Brian ; Gabriel, Christopher...
Bioorganic & Medicinal Chemistry Letters.  24 (2014)  15 - p. 3521-3525 , 2014
Link: https://doi.org/10.1016/..
 
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14

Screening for inhibitors of the hepatitis C virus internal ..:

Zhou, Shou ; Rynearson, Kevin D. ; Ding, Kejia..
Bioorganic & Medicinal Chemistry.  21 (2013)  20 - p. 6139-6144 , 2013
Link: https://doi.org/10.1016/..
 
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15

Synthesis of Oxazole Analogs of Streptolidine Lactam:

Rynearson, Kevin D. ; Dutta, Sanjay ; Tran, Kiet..
European Journal of Organic Chemistry.  2013 (2013)  32 - p. 7337-7342 , 2013
Link: https://doi.org/10.1002/..
 
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