E-LIB Suche - Ergebnisse für: Shipps Jr., Gerald W.

1

MK-8353: Discovery of an Orally Bioavailable Dual Mechanism..:

Boga, Sobhana Babu ; Deng, Yongqi ; Zhu, Liang...
ACS Medicinal Chemistry Letters. 9 (2018) 7 - p. 761-767 , 2018

Link: https://doi.org/10.1021/..

2

Structure–activity relationship study of 4-substituted pipe..:

Tian, Yuan ; Ma, Yao ; Gibeau, Craig R....
Bioorganic & Medicinal Chemistry Letters. 26 (2016) 11 - p. 2735-2738 , 2016

Link: https://doi.org/10.1016/..

3

Discovery of Novel 3,3-Disubstituted Piperidines as Orally ..:

Bogen, Stéphane L. ; Pan, Weidong ; Gibeau, Craig R....
ACS Medicinal Chemistry Letters. 7 (2016) 3 - p. 324-329 , 2016

Link: https://doi.org/10.1021/..

4

Substituted piperidines as HDM2 inhibitors:

Ma, Yao ; Lahue, Brian R. ; Shipps Jr., Gerald W...
Bioorganic & Medicinal Chemistry Letters. 24 (2014) 4 - p. 1026-1030 , 2014

Link: https://doi.org/10.1016/..

5

Modulating the interaction between CDK2 and cyclin A with a..:

Deng, Yongqi ; Shipps Jr., Gerald W. ; Zhao, Lianyun...
Bioorganic & Medicinal Chemistry Letters. 24 (2014) 1 - p. 199-203 , 2014

Link: https://doi.org/10.1016/..

6

Core modification of substituted piperidines as Novel inhib..:

Pan, Weidong ; Lahue, Brian R. ; Ma, Yao...
Bioorganic & Medicinal Chemistry Letters. 24 (2014) 8 - p. 1983-1986 , 2014

Link: https://doi.org/10.1016/..

7

Discovery of Novel, Dual Mechanism ERK Inhibitors by Affini..:

Deng, Yongqi ; Shipps Jr., Gerald W. ; Cooper, Alan...
Journal of Medicinal Chemistry. 57 (2014) 21 - p. 8817-8826 , 2014

Link: https://doi.org/10.1021/..

8

Pivotal Role of an Aliphatic Side Chain in the Development ..:

Ma, Yao ; Lahue, Brian R. ; Gibeau, Craig R....
ACS Medicinal Chemistry Letters. 5 (2014) 5 - p. 572-575 , 2014

Link: https://doi.org/10.1021/..

9

Discovery of liver-targeted inhibitors of stearoyl-CoA desa..:

Deng, Yongqi ; Yang, Zhiwei ; Shipps Jr., Gerald W....
Bioorganic & Medicinal Chemistry Letters. 23 (2013) 3 - p. 791-796 , 2013

Link: https://doi.org/10.1016/..

10

Structure-based design and optimization of 2-aminothiazole-..:

Huang, Xiaohua ; Cheng, Cliff C. ; Fischmann, Thierry O....
Bioorganic & Medicinal Chemistry Letters. 23 (2013) 9 - p. 2590-2594 , 2013

Link: https://doi.org/10.1016/..

11

Discovery of a Novel Series of CHK1 Kinase Inhibitors with ..:

Huang, Xiaohua ; Cheng, Cliff C. ; Fischmann, Thierry O....
ACS Medicinal Chemistry Letters. 3 (2012) 2 - p. 123-128 , 2012

Link: https://doi.org/10.1021/..

12

Discovery and Hit-to-Lead Optimization of Non-ATP Competiti..:

Huang, Xiaohua ; Shipps Jr., Gerald W. ; Cheng, Cliff C....
ACS Medicinal Chemistry Letters. 2 (2011) 8 - p. 632-637 , 2011

Link: https://doi.org/10.1021/..

13

Discovery of novel imidazo[1,2-a]pyrazin-8-amines as Brk/PT..:

Zeng, Hongbo ; Belanger, David B. ; Curran, Patrick J....
Bioorganic & Medicinal Chemistry Letters. 21 (2011) 19 - p. 5870-5875 , 2011

Link: https://doi.org/10.1016/..

14

Small-molecule inhibitors of FABP4/5 ameliorate dyslipidemi..:

Lan, Hong ; Cheng, Cliff C. ; Kowalski, Timothy J....
Journal of Lipid Research. 52 (2011) 4 - p. 646-656 , 2011

Link: https://doi.org/10.1194/..

15

The discovery of novel tartrate-based TNF-α converting enzy..:

Rosner, Kristin E. ; Guo, Zhuyan ; Orth, Peter...
Bioorganic & Medicinal Chemistry Letters. 20 (2010) 3 - p. 1189-1193 , 2010

Link: https://doi.org/10.1016/..