E-LIB Suche - Ergebnisse für: Skene, Robert J

1

Discovery of mobocertinib, a potent, oral inhibitor of EGFR..:

Huang, Wei-Sheng ; Li, Feng ; Gong, Yongjin...
Bioorganic & Medicinal Chemistry Letters. 80 (2023) - p. 129084 , 2023

Link: https://doi.org/10.1016/..

2

Discovery of a Novel Class of d-Amino Acid Oxidase Inhibito..:

Tang, Haifeng ; Jensen, Kristian ; Houang, Evelyne...
Journal of Medicinal Chemistry. 65 (2022) 9 - p. 6775-6802 , 2022

Link: https://doi.org/10.1021/..

3

Efficient synthesis of tert-butyl 3-cyano-3-cyclopropyl-2-o..:

Sasaki, Yusuke ; Tokuhara, Hidekazu ; Ohba, Yusuke...
Bioorganic & Medicinal Chemistry Letters. 30 (2020) 5 - p. 126963 , 2020

Link: https://doi.org/10.1016/..

4

Discovery of a Novel, Highly Potent, and Selective Thieno[3..:

Kurasawa, Osamu ; Miyazaki, Tohru ; Homma, Misaki...
Journal of Medicinal Chemistry. 63 (2020) 3 - p. 1084-1104 , 2020

Link: https://doi.org/10.1021/..

5

Design, Synthesis, and Biological Evaluation of Retinoic Ac..:

Yukawa, Tomoya ; Nara, Yoshi ; Kono, Mitsunori...
Journal of Medicinal Chemistry. 62 (2019) 3 - p. 1167-1179 , 2019

Link: https://doi.org/10.1021/..

6

Design and Synthesis of Conformationally Constrained RORγt ..:

Sato, Ayumu ; Fukase, Yoshiyuki ; Kono, Mitsunori...
ChemMedChem. 14 (2019) 22 - p. 1917-1932 , 2019

Link: https://doi.org/10.1002/..

7

The dynamic conformational landscape of the protein methylt..:

Chen, Shi ; Wiewiora, Rafal P ; Meng, Fanwang...
eLife. 8 (2019) - p. , 2019

Link: https://doi.org/10.7554/..

8

Identification of novel quinazolinedione derivatives as ROR..:

Fukase, Yoshiyuki ; Sato, Ayumu ; Tomata, Yoshihide...
Bioorganic & Medicinal Chemistry. 26 (2018) 3 - p. 721-736 , 2018

Link: https://doi.org/10.1016/..

9

Discovery of [cis-3-({(5R)-5-[(7-Fluoro-1,1-dimethyl-2,3-di..:

Kono, Mitsunori ; Ochida, Atsuko ; Oda, Tsuneo...
Journal of Medicinal Chemistry. 61 (2018) 7 - p. 2973-2988 , 2018

Link: https://doi.org/10.1021/..

10

Discovery of orally efficacious RORγt inverse agonists, par..:

Shirai, Junya ; Tomata, Yoshihide ; Kono, Mitsunori...
Bioorganic & Medicinal Chemistry. 26 (2018) 2 - p. 483-500 , 2018

Link: https://doi.org/10.1016/..

11

Identification of a new class of potent Cdc7 inhibitors des..:

Kurasawa, Osamu ; Oguro, Yuya ; Miyazaki, Tohru...
Bioorganic & Medicinal Chemistry. 25 (2017) 7 - p. 2133-2147 , 2017

Link: https://doi.org/10.1016/..

12

Structure-based optimization of 1 H -imidazole-2-carboxamid..:

Keung, Walter ; Boloor, Amogh ; Brown, Jason...
Bioorganic & Medicinal Chemistry Letters. 27 (2017) 4 - p. 1099-1104 , 2017

Link: https://doi.org/10.1016/..

13

1,2,4-Triazolo-[1,5-a]pyridine HIF Prolylhydroxylase Domain..:

Ahmed, Saleh ; Ayscough, Andrew ; Barker, Greg R....
Journal of Medicinal Chemistry. 60 (2017) 13 - p. 5663-5672 , 2017

Link: https://doi.org/10.1021/..

14

Discovery of a novel prolyl-tRNA synthetase inhibitor and e..:

Adachi, Ryutaro ; Okada, Kengo ; Skene, Robert...
Biochemical and Biophysical Research Communications. 488 (2017) 2 - p. 393-399 , 2017

Link: https://doi.org/10.1016/..

15

Structure-based design and SAR development of 5,6-dihydroim..:

Kiryanov, Andre ; Natala, Srinivasa ; Jones, Benjamin...
Bioorganic & Medicinal Chemistry Letters. 27 (2017) 5 - p. 1311-1315 , 2017

Link: https://doi.org/10.1016/..