E-LIB Suche - Ergebnisse für: Smil, David

1

Discovery of Two Highly Selective Structurally Orthogonal C..:

Němec, Václav ; Remeš, Marek ; Beňovský, Petr...
Journal of Medicinal Chemistry. , 2024

Link: https://doi.org/10.1021/..

2

Discovery of Conformationally Constrained ALK2 Inhibitors:

González-Álvarez, Héctor ; Ensan, Deeba ; Xin, Tao...
Journal of Medicinal Chemistry. 67 (2024) 6 - p. 4707-4725 , 2024

Link: https://doi.org/10.1021/..

3

A non-traditional crystal-based compound screening method t..:

Mrozek, Alexander ; Antoshchenko, Tetyana ; Chen, Yun...
Frontiers in Molecular Biosciences. 9 (2022) - p. , 2022

Link: https://doi.org/10.3389/..

4

Rational Design and Synthesis of Selective PRMT4 Inhibitors..:

Sutherland, Mathew ; Li, Alice ; Kaghad, Anissa...
ChemMedChem. 16 (2021) 7 - p. 1116-1125 , 2021

Link: https://doi.org/10.1002/..

5

Leveraging an open science approach for PET radiotracer dis..:

Murrell, Emily ; Tong, Junchao ; Smil, David...
Nuclear Medicine and Biology. 96-97 (2021) - p. S41 , 2021

Link: https://doi.org/10.1016/..

6

Leveraging Open Science Drug Development for PET: Prelimina..:

Murrell, Emily ; Tong, Junchao ; Smil, David...
ACS Medicinal Chemistry Letters. 12 (2021) 5 - p. 846-850 , 2021

Link: https://doi.org/10.1021/..

7

Probing the SAM Binding Site of SARS-CoV-2 Nsp14 In Vitro U..:

Devkota, Kanchan ; Schapira, Matthieu ; Perveen, Sumera...
SLAS Discovery. 26 (2021) 9 - p. 1200-1211 , 2021

Link: https://doi.org/10.1177/..

8

Leveraging an Open Science Drug Discovery Model to Develop ..:

Smil, David ; Wong, Jong Fu ; Williams, Eleanor P....
Journal of Medicinal Chemistry. 63 (2020) 17 - p. 10061-10085 , 2020

Link: https://doi.org/10.1021/..

9

Targeting ALK2: An Open Science Approach to Developing Ther..:

Ensan, Deeba ; Smil, David ; Zepeda-Velázquez, Carlos A....
Journal of Medicinal Chemistry. 63 (2020) 9 - p. 4978-4996 , 2020

Link: https://doi.org/10.1021/..

10

A chemical biology toolbox to study protein methyltransfera..:

Scheer, Sebastian ; Ackloo, Suzanne ; Medina, Tiago S....
Nature Communications. 10 (2019) 1 - p. , 2019

Link: https://doi.org/10.1038/..

11

Identification and characterization of the first fragment h..:

Mader, Pavel ; Mendoza-Sanchez, Rodrigo ; Iqbal, Aman...
Bioorganic & Medicinal Chemistry. 27 (2019) 17 - p. 3866-3878 , 2019

Link: https://doi.org/10.1016/..

12

Discovery of Potent and Selective Allosteric Inhibitors of ..:

Kaniskan, H. Ümit ; Eram, Mohammad S. ; Zhao, Kehao...
Journal of Medicinal Chemistry. 61 (2018) 3 - p. 1204-1217 , 2018

Link: https://doi.org/10.1021/..

13

Discovery of a Potent, Selective, and Cell-Active Dual Inhi..:

Shen, Yudao ; Szewczyk, Magdalena M. ; Eram, Mohammad S....
Journal of Medicinal Chemistry. 59 (2016) 19 - p. 9124-9139 , 2016

Link: https://doi.org/10.1021/..

14

Discovery of a Potent Class I Protein Arginine Methyltransf..:

Ferreira de Freitas, Renato ; Eram, Mohammad S. ; Szewczyk, Magdalena M....
Journal of Medicinal Chemistry. 59 (2016) 3 - p. 1176-1183 , 2016

Link: https://doi.org/10.1021/..

15

Structure-Based Optimization of a Small Molecule Antagonist..:

Getlik, Matthäus ; Smil, David ; Zepeda-Velázquez, Carlos...
Journal of Medicinal Chemistry. 59 (2016) 6 - p. 2478-2496 , 2016

Link: https://doi.org/10.1021/..