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Stepan, Antonia F.
265  Ergebnisse:
Personensuche X
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1

Discovery of Clinical Candidate PF-06648671: A Potent γ-Sec..:

Pettersson, Martin ; Johnson, Douglas S. ; Humphrey, John M....
Journal of Medicinal Chemistry.  67 (2024)  12 - p. 10248-10262 , 2024
Link: https://doi.org/10.1021/..
 
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2

The Evolving Landscape of Neuroscience Therapeutics: an Int..:

Knoetgen, Hendrik ; Schindler, Torsten ; Schumacher, Felix F....
CHIMIA.  78 (2024)  1/2 - p. 62-66 , 2024
Link: https://doi.org/10.2533/..
 
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3

Enabling late-stage drug diversification by high-throughput..:

Nippa, David F. ; Atz, Kenneth ; Hohler, Remo...
Nature Chemistry.  16 (2023)  2 - p. 239-248 , 2023
Link: https://doi.org/10.1038/..
 
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4

Small-Molecule Lead-Finding Trends across the Roche and Gen..:

Dragovich, Peter S. ; Haap, Wolfgang ; Mulvihill, Melinda M...
Journal of Medicinal Chemistry.  65 (2022)  4 - p. 3606-3615 , 2022
Link: https://doi.org/10.1021/..
 
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5

Late-stage Functionalization and its Impact on Modern Drug ..:

Nippa, David F. ; Hohler, Remo ; Stepan, Antonia F....
CHIMIA.  76 (2022)  3 - p. 258 , 2022
Link: https://doi.org/10.2533/..
 
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6

LipMetE (Lipophilic Metabolism Efficiency) as a Simple Guid..:

Cecere, Giuseppe ; Guasch, Laura ; Olivares-Morales, Andres M...
ACS Medicinal Chemistry Letters.  13 (2022)  9 - p. 1444-1451 , 2022
Link: https://doi.org/10.1021/..
 
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7

The 2ndAlpine Winter Conference on Medicinal and Synthetic ..:

Ciulli, Alessio ; Hamann, Lawrence ; Jahnke, Wolfgang...
ChemMedChem.  16 (2021)  15 - p. 2417-2423 , 2021
Link: https://doi.org/10.1002/..
 
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8

Late-Stage Microsomal Oxidation Reduces Drug–Drug Interacti..:

Stepan, Antonia F. ; Tran, Tuan P. ; Helal, Christopher J....
ACS Medicinal Chemistry Letters.  9 (2018)  2 - p. 68-72 , 2018
Link: https://doi.org/10.1021/..
 
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9

Synthesis and applications of highly functionalized 1-halo-..:

Caputo, Dimitri F. J. ; Arroniz, Carlos ; Dürr, Alexander B....
Chemical Science.  9 (2018)  23 - p. 5295-5300 , 2018
Link: https://doi.org/10.1039/..
 
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10

Lead Diversification at the Nanomole Scale Using Liver Micr..:

Obach, R. Scott ; Walker, Gregory S. ; Sharma, Raman...
Journal of Medicinal Chemistry.  61 (2018)  8 - p. 3626-3640 , 2018
Link: https://doi.org/10.1021/..
 
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11

Discovery and Characterization of (R)-6-Neopentyl-2-(pyridi..:

Stepan, Antonia F. ; Claffey, Michelle M. ; Reese, Matthew R....
Journal of Medicinal Chemistry.  60 (2017)  18 - p. 7764-7780 , 2017
Link: https://doi.org/10.1021/..
 
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12

Discovery of cyclopropyl chromane-derived pyridopyrazine-1,..:

Pettersson, Martin ; Johnson, Douglas S. ; Rankic, Danica A....
MedChemComm.  8 (2017)  4 - p. 730-743 , 2017
Link: https://doi.org/10.1039/..
 
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13

A multi-endpoint matched molecular pair (MMP) analysis of 6..:

Chang, George ; Huard, Kim ; Kauffman, Gregory W...
Bioorganic & Medicinal Chemistry.  25 (2017)  1 - p. 381-388 , 2017
Link: https://doi.org/10.1016/..
 
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14

Oxidative diversification of amino acids and peptides by sm..:

Osberger, Thomas J. ; Rogness, Donald C. ; Kohrt, Jeffrey T...
Nature.  537 (2016)  7619 - p. 214-219 , 2016
Link: https://doi.org/10.1038/..
 
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15

Discovery of indole-derived pyridopyrazine-1,6-dione γ-secr..:

Pettersson, Martin ; Johnson, Douglas S. ; Humphrey, John M....
Bioorganic & Medicinal Chemistry Letters.  25 (2015)  4 - p. 908-913 , 2015
Link: https://doi.org/10.1016/..
 
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