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Thoma, Gebhard
55  Ergebnisse:
Personensuche X
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1

Modelling atopic dermatitis in healthy human skin for the c..:

Hacini‐Rachinel, Feriel ; Hauchard, Alice ; Bruno, Sandro...
Experimental Dermatology.  33 (2024)  5 - p. , 2024
Link: https://doi.org/10.1111/..
 
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2

LTA4H inhibitor LYS006: Clinical PK/PD and safety in a rand..:

Loesche, Christian ; Picard, Damien ; Van Hoorick, Benjamin...
Clinical and Translational Science.  17 (2024)  2 - p. , 2024
Link: https://doi.org/10.1111/..
 
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3

Structure-Guided Elaboration of a Fragment-Like Hit into an..:

Thoma, Gebhard ; Miltz, Wolfgang ; Srinivas, Honnappa...
Journal of Medicinal Chemistry.  67 (2024)  6 - p. 5093-5108 , 2024
Link: https://doi.org/10.1021/..
 
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4

Design of a Supersoft Topical JAK Inhibitor, Which Is Effec..:

Thoma, Gebhard ; Decoret, Odile ; Vangrevelinghe, Eric...
Journal of Medicinal Chemistry.  66 (2023)  21 - p. 15042-15053 , 2023
Link: https://doi.org/10.1021/..
 
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5

Discovery and Characterization of the Topical Soft JAK Inhi..:

Thoma, Gebhard ; Duthaler, Rudolf O. ; Waelchli, Rudolf...
Journal of Medicinal Chemistry.  66 (2023)  3 - p. 2161-2168 , 2023
Link: https://doi.org/10.1021/..
 
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6

Discovery of Amino Alcohols as Highly Potent, Selective, an..:

Thoma, Gebhard ; Markert, Christian ; Lueoend, Rainer...
Journal of Medicinal Chemistry.  66 (2023)  23 - p. 16410-16425 , 2023
Link: https://doi.org/10.1021/..
 
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7

Novel Concept for Super-Soft Topical Drugs: Deactivation by..:

Thoma, Gebhard ; Vangrevelinghe, Eric ; Luneau, Alexandre...
ACS Medicinal Chemistry Letters.  14 (2023)  6 - p. 841-845 , 2023
Link: https://doi.org/10.1021/..
 
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8

Discovery of LYS006, a Potent and Highly Selective Inhibito..:

Markert, Christian ; Thoma, Gebhard ; Srinivas, Honnappa...
Journal of Medicinal Chemistry.  64 (2021)  4 - p. 1889-1903 , 2021
Link: https://doi.org/10.1021/..
 
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9

Orally bioavailable Syk inhibitors with activity in a rat P..:

Thoma, Gebhard ; Veenstra, Siem ; Strang, Ross...
Bioorganic & Medicinal Chemistry Letters.  25 (2015)  20 - p. 4642-4647 , 2015
Link: https://doi.org/10.1016/..
 
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10

Discovery and Profiling of a Selective and Efficacious Syk ..:

Thoma, Gebhard ; Smith, Alexander B. ; van Eis, Maurice J....
Journal of Medicinal Chemistry.  58 (2015)  4 - p. 1950-1963 , 2015
Link: https://doi.org/10.1021/..
 
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11

Selective inhibitors of the Janus kinase Jak3—Are they effe..:

Thoma, Gebhard ; Drückes, Peter ; Zerwes, Hans-Günter
Bioorganic & Medicinal Chemistry Letters.  24 (2014)  19 - p. 4617-4621 , 2014
Link: https://doi.org/10.1016/..
 
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12

Syk inhibitors with high potency in presence of blood:

Thoma, Gebhard ; Blanz, Joachim ; Bühlmayer, Peter...
Bioorganic & Medicinal Chemistry Letters.  24 (2014)  10 - p. 2278-2282 , 2014
Link: https://doi.org/10.1016/..
 
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13

Special ergolines efficiently inhibit the chemokine recepto..:

Thoma, Gebhard ; Baenteli, Rolf ; Lewis, Ian...
Bioorganic & Medicinal Chemistry Letters.  21 (2011)  16 - p. 4745-4749 , 2011
Link: https://doi.org/10.1016/..
 
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14

Jak1 Has a Dominant Role over Jak3 in Signal Transduction t..:

Haan, Claude ; Rolvering, Catherine ; Raulf, Friedrich...
Chemistry & Biology.  18 (2011)  3 - p. 314-323 , 2011
Link: https://doi.org/10.1016/..
 
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15

In vivo Neutralization of Naturally Existing Antibodies aga..:

Duthaler, Rudolf O. ; Ernst, Beat ; Fischer, Reto...
CHIMIA.  64 (2010)  1-2 - p. 23 , 2010
Link: https://doi.org/10.2533/..
 
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