E-LIB Suche - Ergebnisse für: Tokarski, John S.

1

Discovery of 2-(Anilino)pyrimidine-4-carboxamides as Highly..:

Hartz, Richard A. ; Ahuja, Vijay T. ; Luo, Guanglin...
Journal of Medicinal Chemistry. 66 (2023) 11 - p. 7534-7552 , 2023

Link: https://doi.org/10.1021/..

2

Development of BET Inhibitors as Potential Treatments for C..:

Hill, Matthew D. ; Fang, Haiquan ; Norris, Derek...
ACS Medicinal Chemistry Letters. 13 (2022) 7 - p. 1165-1171 , 2022

Link: https://doi.org/10.1021/..

3

Discovery and Preclinical Pharmacology of an Oral Bromodoma..:

Gavai, Ashvinikumar V. ; Norris, Derek ; Delucca, George...
Journal of Medicinal Chemistry. 64 (2021) 19 - p. 14247-14265 , 2021

Link: https://doi.org/10.1021/..

4

An innovative kinome platform to accelerate small-molecule ..:

Chaudhry, Charu ; Tebben, Andrew ; Tokarski, John S....
Drug Discovery Today. 26 (2021) 5 - p. 1115-1125 , 2021

Link: https://doi.org/10.1016/..

5

Discovery of BMS-986202: A Clinical Tyk2 Inhibitor that Bin..:

Liu, Chunjian ; Lin, James ; Langevine, Charles...
Journal of Medicinal Chemistry. 64 (2020) 1 - p. 677-694 , 2020

Link: https://doi.org/10.1021/..

6

Identification of N-Methyl Nicotinamide and N-Methyl Pyrida..:

Moslin, Ryan ; Zhang, Yanlei ; Wrobleski, Stephen T....
Journal of Medicinal Chemistry. 62 (2019) 20 - p. 8953-8972 , 2019

Link: https://doi.org/10.1021/..

7

Identification of Imidazo[1,2-b]pyridazine Derivatives as P..:

Liu, Chunjian ; Lin, James ; Moslin, Ryan...
ACS Medicinal Chemistry Letters. 10 (2019) 3 - p. 383-388 , 2019

Link: https://doi.org/10.1021/..

8

Highly Selective Inhibition of Tyrosine Kinase 2 (TYK2) for..:

Wrobleski, Stephen T. ; Moslin, Ryan ; Lin, Shuqun...
Journal of Medicinal Chemistry. 62 (2019) 20 - p. 8973-8995 , 2019

Link: https://doi.org/10.1021/..

9

Discovery of potent and efficacious pyrrolopyridazines as d..:

Hynes Jr., John ; Wu, Hong ; Kempson, James...
Bioorganic & Medicinal Chemistry Letters. 27 (2017) 14 - p. 3101-3106 , 2017

Link: https://doi.org/10.1016/..

10

Discovery of a Highly Selective JAK2 Inhibitor, BMS-911543,..:

Wan, Honghe ; Schroeder, Gretchen M. ; Hart, Amy C....
ACS Medicinal Chemistry Letters. 6 (2015) 8 - p. 850-855 , 2015

Link: https://doi.org/10.1021/..

11

9H-Carbazole-1-carboxamides as potent and selective JAK2 in..:

Zimmermann, Kurt ; Sang, Xiaopeng ; Mastalerz, Harold A....
Bioorganic & Medicinal Chemistry Letters. 25 (2015) 14 - p. 2809-2812 , 2015

Link: https://doi.org/10.1016/..

12

Correction to N-(Cycloalkylamino)acyl-2-aminothiazole Inhib..:

Misra, Raj N. ; Xiao, Hai-yun ; Kim, Kyoung S....
Journal of Medicinal Chemistry. 58 (2015) 18 - p. 7609-7609 , 2015

Link: https://doi.org/10.1021/..

13

Structure-Based Design of Selective Janus Kinase 2 Imidazo[..:

Hart, Amy C. ; Schroeder, Gretchen M. ; Wan, Honghe...
ACS Medicinal Chemistry Letters. 6 (2015) 8 - p. 845-849 , 2015

Link: https://doi.org/10.1021/..

14

Tyrosine Kinase 2-mediated Signal Transduction in T Lymphoc..:

Tokarski, John S. ; Zupa-Fernandez, Adriana ; Tredup, Jeffrey A....
Journal of Biological Chemistry. 290 (2015) 17 - p. 11061-11074 , 2015

Link: https://doi.org/10.1074/..

15

Discovery of pyrrolo[1,2-b]pyridazine-3-carboxamides as Jan..:

Duan, James J.-W. ; Lu, Zhonghui ; Jiang, Bin...
Bioorganic & Medicinal Chemistry Letters. 24 (2014) 24 - p. 5721-5726 , 2014

Link: https://doi.org/10.1016/..