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Varnes, Jeffrey G.
44  Ergebnisse:
Personensuche X
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1

Discovery of a Series of 7-Azaindoles as Potent and Highly ..:

Barlaam, Bernard ; De Savi, Chris ; Dishington, Allan...
Journal of Medicinal Chemistry.  64 (2021)  20 - p. 15189-15213 , 2021
Link: https://doi.org/10.1021/..
 
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2

Addition of Fluorine and a Late-Stage Functionalization (LS..:

Scott, James S. ; Moss, Thomas A. ; Barlaam, Bernard...
ACS Medicinal Chemistry Letters.  11 (2020)  12 - p. 2519-2525 , 2020
Link: https://doi.org/10.1021/..
 
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3

Structure‐Based Design of Selective Noncovalent CDK12 Inhib..:

Johannes, Jeffrey W. ; Denz, Christopher R. ; Su, Nancy...
ChemMedChem.  13 (2018)  3 - p. 231-235 , 2018
Link: https://doi.org/10.1002/..
 
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4

Bicyclo((aryl)methyl)benzamides as inhibitors of GlyT1:

Varnes, Jeffrey G. ; Xiong, Hui ; Forst, Janet M....
Bioorganic & Medicinal Chemistry Letters.  28 (2018)  6 - p. 1043-1049 , 2018
Link: https://doi.org/10.1016/..
 
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5

General methods for the synthesis and late-stage diversific..:

Varnes, Jeffrey G. ; McGuire, Thomas ; Meadows, Rebecca E....
Tetrahedron Letters.  57 (2016)  42 - p. 4718-4722 , 2016
Link: https://doi.org/10.1016/..
 
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6

Optimization of Highly Kinase Selective Bis-anilino Pyrimid..:

McCoull, William ; Hennessy, Edward J. ; Blades, Kevin...
ACS Medicinal Chemistry Letters.  7 (2016)  12 - p. 1118-1123 , 2016
Link: https://doi.org/10.1021/..
 
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7

Fragment-assisted hit investigation involving integrated HT..:

Varnes, Jeffrey G. ; Geschwindner, Stefan ; Holmquist, Christopher R....
Bioorganic & Medicinal Chemistry Letters.  26 (2016)  1 - p. 197-202 , 2016
Link: https://doi.org/10.1016/..
 
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8

Towards the next generation of dual Bcl-2/Bcl-xL inhibitors:

Varnes, Jeffrey G. ; Gero, Thomas ; Huang, Shan...
Bioorganic & Medicinal Chemistry Letters.  24 (2014)  14 - p. 3026-3033 , 2014
Link: https://doi.org/10.1016/..
 
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9

Identification and optimisation of 7-azaindole PAK1 inhibit..:

McCoull, William ; Hennessy, Edward J. ; Blades, Kevin...
Med. Chem. Commun..  5 (2014)  10 - p. 1533-1539 , 2014
Link: https://doi.org/10.1039/..
 
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10

Discovery of novel positive allosteric modulators of the me..:

Varnes, Jeffrey G. ; Marcus, Andrew P. ; Mauger, Russell C....
Bioorganic & Medicinal Chemistry Letters.  21 (2011)  5 - p. 1402-1406 , 2011
Link: https://doi.org/10.1016/..
 
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11

Efficient preparation of 2,4-methanoproline:

Varnes, Jeffrey G. ; Scott Lehr, G. ; Moore, Gary L...
Tetrahedron Letters.  51 (2010)  29 - p. 3756-3758 , 2010
Link: https://doi.org/10.1016/..
 
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12

Efficient synthesis of a 7-azabicyclo[2.2.1]heptane based G..:

Xiong, Hui ; Frietze, William ; Andisik, Donald W....
Tetrahedron Letters.  51 (2010)  51 - p. 6741-6744 , 2010
Link: https://doi.org/10.1016/..
 
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13

Identification of N-(2-(azepan-1-yl)-2-phenylethyl)-benzene..:

Varnes, Jeffrey G. ; Forst, Janet M. ; Hoerter, Tiffany N....
Bioorganic & Medicinal Chemistry Letters.  20 (2010)  16 - p. 4878-4881 , 2010
Link: https://doi.org/10.1016/..
 
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14

Structure–activity relationship and pharmacokinetic profile..:

Varnes, Jeffrey G. ; Wacker, Dean A. ; Pinto, Donald J.P....
Bioorganic & Medicinal Chemistry Letters.  18 (2008)  2 - p. 749-754 , 2008
Link: https://doi.org/10.1016/..
 
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15

Discovery of (R)-9-Ethyl-1,3,4,10b-tetrahydro-7-trifluorome..:

Wacker, Dean A. ; Varnes, Jeffrey G. ; Malmstrom, Sarah E....
Journal of Medicinal Chemistry.  50 (2007)  6 - p. 1365-1379 , 2007
Link: https://doi.org/10.1021/..
 
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