E-LIB Suche - Ergebnisse für: Wesolowski, Gregg

1

Lead optimization of cathepsin K inhibitors for the treatme..:

Ginnetti, Anthony T. ; Paone, Daniel V. ; Nanda, Kausik K....
Bioorganic & Medicinal Chemistry Letters. 74 (2022) - p. 128927 , 2022

Link: https://doi.org/10.1016/..

2

Preclinical evaluation of [11C]L‐235 as a radioligand for P..:

Bennacef, Idriss ; Rubins, Daniel ; Riffel, Kerry...
Journal of Labelled Compounds and Radiopharmaceuticals. 64 (2020) 4 - p. 159-167 , 2020

Link: https://doi.org/10.1002/..

3

Suppression of cathepsin K biomarker in synovial fluid as a..:

Ma, Bennett ; Wesolowski, Gregg ; Luo, Bin...
Journal of Circulating Biomarkers. 8 (2019) 1 - p. , 2019

Link: https://doi.org/10.33393..

4

Applicability of in vitro-in vivo translation of cathepsin ..:

Ma, Bennett ; Luo, Bin ; Euler, Danielle H....
Naunyn-Schmiedeberg's Archives of Pharmacology. 390 (2017) 4 - p. 435-441 , 2017

Link: https://doi.org/10.1007/..

5

Determination of in Vivo Enzyme Occupancy Utilizing Inhibit..:

Murphy, Dennis J. ; Ou, Yangsi ; Euler, Danielle H....
Journal of the American Chemical Society. 137 (2015) 35 - p. 11230-11233 , 2015

Link: https://doi.org/10.1021/..

6

Inhibition of cathepsin K reduces cartilage degeneration in..:

Hayami, Tadashi ; Zhuo, Ya ; Wesolowski, Gregg A...
Bone. 50 (2012) 6 - p. 1250-1259 , 2012

Link: https://doi.org/10.1016/..

7

Odanacatib reduces bone turnover and increases bone mass in..:

Masarachia, Patricia J ; Pennypacker, Brenda L ; Pickarski, Maureen...
Journal of Bone and Mineral Research. 27 (2011) 3 - p. 509-523 , 2011

Link: https://doi.org/10.1002/..

8

Difluoroethylamines as an amide isostere in inhibitors of c..:

Isabel, Elise ; Mellon, Christophe ; Boyd, Michael J....
Bioorganic & Medicinal Chemistry Letters. 21 (2011) 3 - p. 920-923 , 2011

Link: https://doi.org/10.1016/..

9

The discovery of MK-0674, an orally bioavailable cathepsin ..:

Isabel, Elise ; Bateman, Kevin P. ; Chauret, Nathalie...
Bioorganic & Medicinal Chemistry Letters. 20 (2010) 3 - p. 887-892 , 2010

Link: https://doi.org/10.1016/..

10

Identification of a Nonbasic, Nitrile-Containing Cathepsin ..:

Robichaud, Jöel ; Black, W. Cameron ; Thérien, Michel...
Journal of Medicinal Chemistry. 51 (2008) 20 - p. 6410-6420 , 2008

Link: https://doi.org/10.1021/..

11

P6. Anti-resorptive and potential anti-invasion effects of ..:

Leung, Patrick ; Pickarski, Maureen ; Wesolowski, Gregg A..
Cancer Treatment Reviews. 34 (2008) - p. 14 , 2008

Link: https://doi.org/10.1016/..

12

The discovery of odanacatib (MK-0822), a selective inhibito..:

Gauthier, Jacques Yves ; Chauret, Nathalie ; Cromlish, Wanda...
Bioorganic & Medicinal Chemistry Letters. 18 (2008) 3 - p. 923-928 , 2008

Link: https://doi.org/10.1016/..

13

β-Substituted cyclohexanecarboxamide cathepsin K inhibitors..:

Robichaud, Joël ; Bayly, Christopher I. ; Black, W. Cameron...
Bioorganic & Medicinal Chemistry Letters. 17 (2007) 11 - p. 3146-3151 , 2007

Link: https://doi.org/10.1016/..

14

Inverse relationship between matrix remodeling and lipid me..:

Watters, James W. ; Cheng, Chun ; Pickarski, Maureen...
Arthritis & Rheumatism. 56 (2007) 9 - p. 2999-3009 , 2007

Link: https://doi.org/10.1002/..

15

Design and synthesis of tetracyclic nonpeptidic biaryl nitr..:

Setti, Eduardo L. ; Venkatraman, Shankar ; Palmer, James T....
Bioorganic & Medicinal Chemistry Letters. 16 (2006) 16 - p. 4296-4299 , 2006

Link: https://doi.org/10.1016/..