E-LIB Suche - Ergebnisse für: Wigle, Tim J.

1

Targeted Degradation of PARP14 Using a Heterobifunctional S..:

Wigle, Tim J. ; Ren, Yue ; Molina, Jennifer R....
ChemBioChem. 22 (2021) 12 - p. 2107-2110 , 2021

Link: https://doi.org/10.1002/..

2

Forced Self-Modification Assays as a Strategy to Screen Mon..:

Wigle, Tim J. ; Church, W. David ; Majer, Christina R....
SLAS Discovery. 25 (2020) 3 - p. 241-252 , 2020

Link: https://doi.org/10.1177/..

3

Enabling drug discovery for the PARP protein family through..:

Lu, Alvin Z. ; Abo, Ryan ; Ren, Yue...
Biochemical Pharmacology. 167 (2019) - p. 97-106 , 2019

Link: https://doi.org/10.1016/..

4

Small molecule inhibitors and CRISPR/Cas9 mutagenesis demon..:

Thomenius, Michael J. ; Totman, Jennifer ; Harvey, Darren...
PLOS ONE. 13 (2018) 6 - p. e0197372 , 2018

Link: https://doi.org/10.1371/..

5

Identification of a peptide inhibitor for the histone methy..:

Morrison, Michael J. ; Boriack-Sjodin, P. Ann ; Swinger, Kerren K....
PLOS ONE. 13 (2018) 5 - p. e0197082 , 2018

Link: https://doi.org/10.1371/..

6

Characterization of the Enzymatic Activity of SETDB1 and It..:

Basavapathruni, Aravind ; Gureasko, Jodi ; Porter Scott, Margaret...
Biochemistry. 55 (2016) 11 - p. 1645-1651 , 2016

Link: https://doi.org/10.1021/..

7

The Importance of Being Me: Magic Methyls, Methyltransferas..:

Kuntz, Kevin W. ; Campbell, John E. ; Keilhack, Heike...
Journal of Medicinal Chemistry. 59 (2016) 4 - p. 1556-1564 , 2016

Link: https://doi.org/10.1021/..

8

EPZ011989, A Potent, Orally-Available EZH2 Inhibitor with R..:

Campbell, John E. ; Kuntz, Kevin W. ; Knutson, Sarah K....
ACS Medicinal Chemistry Letters. 6 (2015) 5 - p. 491-495 , 2015

Link: https://doi.org/10.1021/..

9

Novel Oxindole Sulfonamides and Sulfamides: EPZ031686, the ..:

Mitchell, Lorna H. ; Boriack-Sjodin, P. Ann ; Smith, Sherri...
ACS Medicinal Chemistry Letters. 7 (2015) 2 - p. 134-138 , 2015

Link: https://doi.org/10.1021/..

10

Aryl Pyrazoles as Potent Inhibitors of Arginine Methyltrans..:

Mitchell, Lorna H. ; Drew, Allison E. ; Ribich, Scott A....
ACS Medicinal Chemistry Letters. 6 (2015) 6 - p. 655-659 , 2015

Link: https://doi.org/10.1021/..

11

A High-Throughput Mass Spectrometry Assay Coupled with Redo..:

Wigle, Tim J. ; Swinger, Kerren K. ; Campbell, John E....
SLAS Discovery. 20 (2015) 6 - p. 810-820 , 2015

Link: https://doi.org/10.1177/..

12

Synergistic Anti-Tumor Activity of EZH2 Inhibitors and Gluc..:

Knutson, Sarah K. ; Warholic, Natalie M. ; Johnston, L. Danielle...
PLoS ONE. 9 (2014) 12 - p. e111840 , 2014

Link: https://doi.org/10.1371/..

13

Reaction Coupling between Wild-Type and Disease-Associated ..:

Swalm, Brooke M. ; Knutson, Sarah K. ; Warholic, Natalie M....
ACS Chemical Biology. 9 (2014) 11 - p. 2459-2464 , 2014

Link: https://doi.org/10.1021/..

14

Durable tumor regression in genetically altered malignant r..:

Knutson, Sarah K. ; Warholic, Natalie M. ; Wigle, Tim J....
Proceedings of the National Academy of Sciences. 110 (2013) 19 - p. 7922-7927 , 2013

Link: https://doi.org/10.1073/..

15

Drugging the human methylome: an emerging modality for reve..:

Wigle, Tim J ; Copeland, Robert A
Current Opinion in Chemical Biology. 17 (2013) 3 - p. 369-378 , 2013

Link: https://doi.org/10.1016/..