E-LIB Suche - Ergebnisse für: Willis, Nicky J.

1

Designed switch from covalent to non-covalent inhibitors of..:

Atkinson, Benjamin N. ; Willis, Nicky J. ; Zhao, Yuguang...
European Journal of Medicinal Chemistry. 251 (2023) - p. 115132 , 2023

Link: https://doi.org/10.1016/..

2

Design of a Potent, Selective, and Brain-Penetrant Inhibito..:

Willis, Nicky J. ; Mahy, William ; Sipthorp, James...
Journal of Medicinal Chemistry. 65 (2022) 10 - p. 7212-7230 , 2022

Link: https://doi.org/10.1021/..

3

Structure-activity relationships of 2-pyrimidinecarbohydraz..:

Chatzopoulou, Maria ; Conole, Daniel ; Emer, Enrico...
Bioorganic & Medicinal Chemistry. 69 (2022) - p. 116812 , 2022

Link: https://doi.org/10.1016/..

4

Structural Analysis and Development of Notum Fragment Scree..:

Zhao, Yuguang ; Mahy, William ; Willis, Nicky J....
ACS Chemical Neuroscience. 13 (2022) 13 - p. 2060-2077 , 2022

Link: https://doi.org/10.1021/..

5

Large-scale synthesis of Notum inhibitor 1-(2,4-dichloro-3-..:

Atkinson, Benjamin N. ; Willis, Nicky J. ; Smith, Jennifer...
RSC Advances. 12 (2022) 41 - p. 26497-26503 , 2022

Link: https://doi.org/10.1039/..

6

Structural Requirements for Dihydrobenzoxazepinone Anthelmi..:

Partridge, Frederick A. ; Bataille, Carole J.R. ; Forman, Ruth...
ACS Infectious Diseases. 7 (2021) 5 - p. 1260-1274 , 2021

Link: https://doi.org/10.1021/..

7

NOTUM from Apc-mutant cells biases clonal competition to in..:

Flanagan, Dustin J. ; Pentinmikko, Nalle ; Luopajärvi, Kalle...
Nature. 594 (2021) 7863 - p. 430-435 , 2021

Link: https://doi.org/10.1038/..

8

Virtual Screening Directly Identifies New Fragment-Sized In..:

Steadman, David ; Atkinson, Benjamin N. ; Zhao, Yuguang...
Journal of Medicinal Chemistry. 65 (2021) 1 - p. 562-578 , 2021

Link: https://doi.org/10.1021/..

9

Discovery and mechanism of action studies of 4,6-diphenylpy..:

Vuorinen, Aini ; Wilkinson, Isabel V.L. ; Chatzopoulou, Maria...
European Journal of Medicinal Chemistry. 220 (2021) - p. 113431 , 2021

Link: https://doi.org/10.1016/..

10

Carboxylesterase Notum Is a Druggable Target to Modulate Wn..:

Bayle, Elliott D. ; Svensson, Fredrik ; Atkinson, Benjamin N....
Journal of Medicinal Chemistry. 64 (2021) 8 - p. 4289-4311 , 2021

Link: https://doi.org/10.1021/..

11

Screening of a Custom-Designed Acid Fragment Library Identi..:

Mahy, William ; Patel, Mikesh ; Steadman, David...
Journal of Medicinal Chemistry. 63 (2020) 17 - p. 9464-9483 , 2020

Link: https://doi.org/10.1021/..

12

5-Phenyl-1,3,4-oxadiazol-2(3H)-ones Are Potent Inhibitors o..:

Mahy, William ; Willis, Nicky J. ; Zhao, Yuguang...
Journal of Medicinal Chemistry. 63 (2020) 21 - p. 12942-12956 , 2020

Link: https://doi.org/10.1021/..

13

An improved, scalable synthesis of Notum inhibitor LP-92205..:

Willis, Nicky J ; Bayle, Elliott D ; Papageorgiou, George...
Beilstein Journal of Organic Chemistry. 15 (2019) - p. 2790-2797 , 2019

Link: https://doi.org/10.3762/..

14

Isolation, Structural Identification, Synthesis, and Pharma..:

Chatzopoulou, Maria ; Claridge, Tim D. W. ; Davies, Kay E....
Journal of Medicinal Chemistry. 63 (2019) 5 - p. 2547-2556 , 2019

Link: https://doi.org/10.1021/..

15

Corrigendum to "Single-molecule in vivo imaging of bacteria..:

Llorente-Garcia, Isabel ; Lenn, Tchern ; Erhardt, Heiko...
Biochimica et Biophysica Acta (BBA) - Bioenergetics. 1859 (2018) 2 - p. 164 , 2018

Link: https://doi.org/10.1016/..