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de Bruin, Gerjan
34  Ergebnisse:
Personensuche X
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1

Mutational profile of previously treated chronic lymphocyti..:

Woyach, Jennifer A. ; Jones, Daniel ; Jurczak, Wojciech...
Blood Journal.  , 2024
Link: https://doi.org/10.1182/..
 
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2

Immunoproteasomal Inhibition With ONX-0914 Attenuates Ather..:

Schaftenaar, Frank H. ; van Dam, Andrea D. ; de Bruin, Gerjan...
Arteriosclerosis, Thrombosis, and Vascular Biology.  44 (2024)  6 - p. 1346-1364 , 2024
Link: https://doi.org/10.1161/..
 
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3

Discovery of quinoline-based irreversible BTK inhibitors:

de Bruin, Gerjan ; Demont, Dennis ; de Zwart, Edwin...
Bioorganic & Medicinal Chemistry Letters.  30 (2020)  14 - p. 127261 , 2020
Link: https://doi.org/10.1016/..
 
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4

Potency and Selectivity of BTK Inhibitors in Clinical Devel..:

Kaptein, Allard ; de Bruin, Gerjan ; Hoek, Maaike Emmelot-van...
Clinical Lymphoma Myeloma and Leukemia.  19 (2019)  - p. S316-S317 , 2019
Link: https://doi.org/10.1016/..
 
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5

Two‐Step Bioorthogonal Activity‐Based Protein Profiling of ..:

Xin, Bo‐Tao ; Espinal, Christofer ; Bruin, Gerjan...
ChemBioChem.  21 (2019)  1-2 - p. 248-255 , 2019
Link: https://doi.org/10.1002/..
 
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6

Structure-Based Design of Inhibitors Selective for Human Pr..:

Xin, Bo-Tao ; Huber, Eva M. ; de Bruin, Gerjan...
Journal of Medicinal Chemistry.  62 (2019)  3 - p. 1626-1642 , 2019
Link: https://doi.org/10.1021/..
 
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7

Asymmetric Synthesis of Lysine Analogues with Reduced Basic..:

de Bruin, Gerjan ; van Rooden, Eva J. ; Ward, David...
European Journal of Organic Chemistry.  2017 (2017)  39 - p. 5921-5934 , 2017
Link: https://doi.org/10.1002/..
 
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8

Amelioration of autoimmunity with an inhibitor selectively ..:

Basler, Michael ; Maurits, Elmer ; de Bruin, Gerjan...
British Journal of Pharmacology.  175 (2017)  1 - p. 38-52 , 2017
Link: https://doi.org/10.1111/..
 
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9

Enantioselective synthesis of adamantylalanine and carboran..:

de Bruin, Gerjan ; Mock, Elliot D. ; Hoogendoorn, Sascha...
Chemical Communications.  52 (2016)  21 - p. 4064-4067 , 2016
Link: https://doi.org/10.1039/..
 
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10

Structure-Based Design of β5c Selective Inhibitors of Human..:

Xin, Bo-Tao ; de Bruin, Gerjan ; Huber, Eva M....
Journal of Medicinal Chemistry.  59 (2016)  15 - p. 7177-7187 , 2016
Link: https://doi.org/10.1021/..
 
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11

The immunoproteasomes are key to regulate myokines and MHC ..:

Bhattarai, Salyan ; Ghannam, Khetam ; Krause, Sabine...
Journal of Autoimmunity.  75 (2016)  - p. 118-129 , 2016
Link: https://doi.org/10.1016/..
 
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12

Proteasome Subunit Selective Activity-Based Probes Report o..:

de Bruin, Gerjan ; Xin, Bo-Tao ; Florea, Bogdan I..
Journal of the American Chemical Society.  138 (2016)  31 - p. 9874-9880 , 2016
Link: https://doi.org/10.1021/..
 
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13

Incorporation of the Constrained Peptidomimetic, 5‐Methylpy..:

Xin, Bo‐Tao ; de Bruin, Gerjan ; Plomp, Jan‐Willem...
European Journal of Organic Chemistry.  2016 (2016)  6 - p. 1132-1144 , 2016
Link: https://doi.org/10.1002/..
 
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14

A humanized yeast proteasome identifies unique binding mode..:

Huber, Eva M ; Heinemeyer, Wolfgang ; de Bruin, Gerjan..
The EMBO Journal.  35 (2016)  23 - p. 2602-2613 , 2016
Link: https://doi.org/10.15252..
 
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15

Systematic Analyses of Substrate Preferences of 20S Proteas..:

Huber, Eva M. ; de Bruin, Gerjan ; Heinemeyer, Wolfgang...
Journal of the American Chemical Society.  137 (2015)  24 - p. 7835-7842 , 2015
Link: https://doi.org/10.1021/..
 
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