E-LIB Suche - Ergebnisse für: van Montfort, RLM

1

Determination of Ligand-Binding Affinity (Kd) Using Transve..:

Liu, M ; Mirza, A ; McAndrew, PC...
Journal of Medicinal Chemistry, 2023, 66 (15), pp. 10617 - 10627. , 2024

2

Determination of Ligand-Binding Affinity (Kd) Using Transve..:

Liu, M ; Mirza, A ; McAndrew, PC...
https://discovery.ucl.ac.uk/id/eprint/10184909/1/Determination%20of%20Ligand-Binding%20Affinity%20%28iKisubdsub%29%20Using%20Transverse%20Relaxation%20Rate%20%28iRisub2sub%29%20in%20the%20Ligand-Observed%20s.pdf. , 2023

Link: https://discovery.ucl.ac..

3

iTAG an optimized IMiD-induced degron for targeted protein ..:

Bouguenina, H ; Nicolaou, S ; Le Bihan, Y-V...
107059. , 2023

Link: https://repository.icr.a..

4

Discovery of an In Vivo Chemical Probe for BCL6 Inhibition ..:

Harnden, AC ; Davis, OA ; Box, GM...
Journal of Medicinal Chemistry, 2023, 66 (8), pp. 5892 - 5906. , 2023

Link: https://repository.icr.a..

5

Discovering cell-active BCL6 inhibitors: effectively combin..:

Pierrat, OA ; Liu, M ; Collie, GW...
18633. , 2022

Link: https://doi.org/10.1038/..

6

Into Deep Water: Optimizing BCL6 Inhibitors by Growing into..:

Lloyd, MG ; Huckvale, R ; Cheung, K-MJ...
Journal of medicinal chemistry, 2021, 64 (23), pp. 17079 - 17097. , 2022

Link: https://repository.icr.a..

7

Improved Binding Affinity and Pharmacokinetics Enable Susta..:

Huckvale, R ; Harnden, AC ; Cheung, K-MJ...
Journal of Medicinal Chemistry, 2022, 65 (12), pp. 8191 - 8207. , 2022

Link: https://repository.icr.a..

8

Optimizing Shape Complementarity Enables the Discovery of P..:

Davis, OA ; Cheung, K-MJ ; Brennan, A...
Journal of Medicinal Chemistry, 2022, 65 (12), pp. 8169 - 8190. , 2022

Link: https://repository.icr.a..

9

C8-substituted pyrido[3,4-d]pyrimidin-4(3H)-ones: Studies t..:

Le Bihan, Y-V ; Lanigan, RM ; Atrash, B...
European journal of medicinal chemistry, 2019, 177 pp. 316 - 337. , 2020

Link: https://repository.icr.a..

10

8-Substituted Pyrido[3,4-d]pyrimidin-4(3H)-one Derivatives ..:

Bavetsias, V ; Lanigan, RM ; Ruda, GF...
Journal of medicinal chemistry, 2016, 59 (4), pp. 1388 - 1409. , 2020

Link: https://repository.icr.a..

11

Structural and functional characterisation of human RNA hel..:

Felisberto-Rodrigues, C ; Thomas, JC ; McAndrew, C...
The Biochemical journal, 2019, 476 (18), pp. 2521 - 2543. , 2020

Link: https://repository.icr.a..

12

Achieving In Vivo Target Depletion through the Discovery an..:

Bellenie, BR ; Cheung, K-MJ ; Varela, A...
Journal of medicinal chemistry, 2020, 63 (8), pp. 4047 - 4068. , 2020

Link: https://repository.icr.a..

13

Achieving In Vivo Target Depletion through the Discovery an..:

Bellenie, BR ; Cheung, K-MJ ; Varela, A...
https://discovery.ucl.ac.uk/id/eprint/10096411/1/acs.jmedchem.9b02076.pdf. , 2020

Link: https://discovery.ucl.ac..

14

High Proliferation Rate and a Compromised Spindle Assembly ..:

Anderhub, SJ ; Mak, GW-Y ; Gurden, MD...
Molecular cancer therapeutics, 2019, 18 (10), pp. 1696 - 1707. , 2019

Link: https://repository.icr.a..

15

High Proliferation Rate and a Compromised Spindle Assembly ..:

Anderhub, SJ ; Mak, GW-Y ; Gurden, MD...
https://discovery.ucl.ac.uk/id/eprint/10084031/1/MCT%20pdf.pdf. , 2019

Link: https://discovery.ucl.ac..