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Cheung, Kwai-Ming
197
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1
A RIPK1-specific PROTAC degrader achieves potent antitumor ..:
Mannion, Jonathan
;
Gifford, Valentina
;
Bellenie, Benjamin
...
Immunity. 57 (2024) 7 - p. 1514-1532.e15 , 2024
Link:
https://doi.org/10.1016/..
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2
Discovery of an In Vivo Chemical Probe for BCL6 Inhibition ..:
Harnden, Alice C.
;
Davis, Owen A.
;
Box, Gary M.
...
Journal of Medicinal Chemistry. 66 (2023) 8 - p. 5892-5906 , 2023
Link:
https://doi.org/10.1021/..
?
3
Optimizing Shape Complementarity Enables the Discovery of P..:
Davis, Owen A.
;
Cheung, Kwai-Ming J.
;
Brennan, Alfie
...
Journal of Medicinal Chemistry. 65 (2022) 12 - p. 8169-8190 , 2022
Link:
https://doi.org/10.1021/..
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4
Discovering cell-active BCL6 inhibitors: effectively combin..:
Pierrat, Olivier A.
;
Liu, Manjuan
;
Collie, Gavin W.
...
Scientific Reports. 12 (2022) 1 - p. , 2022
Link:
https://doi.org/10.1038/..
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5
Improved Binding Affinity and Pharmacokinetics Enable Susta..:
Huckvale, Rosemary
;
Harnden, Alice C.
;
Cheung, Kwai-Ming J.
...
Journal of Medicinal Chemistry. 65 (2022) 12 - p. 8191-8207 , 2022
Link:
https://doi.org/10.1021/..
?
6
Into Deep Water: Optimizing BCL6 Inhibitors by Growing into..:
Lloyd, Matthew G.
;
Huckvale, Rosemary
;
Cheung, Kwai-Ming J.
...
Journal of Medicinal Chemistry. 64 (2021) 23 - p. 17079-17097 , 2021
Link:
https://doi.org/10.1021/..
?
7
Achieving In Vivo Target Depletion through the Discovery an..:
Bellenie, Benjamin R.
;
Cheung, Kwai-Ming J.
;
Varela, Ana
...
Journal of Medicinal Chemistry. 63 (2020) 8 - p. 4047-4068 , 2020
Link:
https://doi.org/10.1021/..
?
8
Introduction of a Methyl Group Curbs Metabolism of Pyrido[3..:
Woodward, Hannah L.
;
Innocenti, Paolo
;
Cheung, Kwai-Ming J.
...
Journal of Medicinal Chemistry. 61 (2018) 18 - p. 8226-8240 , 2018
Link:
https://doi.org/10.1021/..
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9
Multiparameter Lead Optimization to Give an Oral Checkpoint..:
Osborne, James D.
;
Matthews, Thomas P.
;
McHardy, Tatiana
...
Journal of Medicinal Chemistry. 59 (2016) 11 - p. 5221-5237 , 2016
Link:
https://doi.org/10.1021/..
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10
Structure-Based Design of Orally Bioavailable 1H-Pyrrolo[3,..:
Naud, Sébastien
;
Westwood, Isaac M.
;
Faisal, Amir
...
Journal of Medicinal Chemistry. 56 (2013) 24 - p. 10045-10065 , 2013
Link:
https://doi.org/10.1021/..
?
11
Design of Potent and Selective Hybrid Inhibitors of the Mit..:
Innocenti, Paolo
;
Cheung, Kwai-Ming J.
;
Solanki, Savade
...
Journal of Medicinal Chemistry. 55 (2012) 7 - p. 3228-3241 , 2012
Link:
https://doi.org/10.1021/..
?
12
Structure-Guided Evolution of Potent and Selective CHK1 Inh..:
Reader, John C.
;
Matthews, Thomas P.
;
Klair, Suki
...
Journal of Medicinal Chemistry. 54 (2011) 24 - p. 8328-8342 , 2011
Link:
https://doi.org/10.1021/..
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13
Aminopyrazine Inhibitors Binding to an Unusual Inactive Con..:
Whelligan, Daniel K.
;
Solanki, Savade
;
Taylor, Dawn
...
Journal of Medicinal Chemistry. 53 (2010) 21 - p. 7682-7698 , 2010
Link:
https://doi.org/10.1021/..
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14
Discovery of 4-Amino-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pip..:
McHardy, Tatiana
;
Caldwell, John J.
;
Cheung, Kwai-Ming
...
Journal of Medicinal Chemistry. 53 (2010) 5 - p. 2239-2249 , 2010
Link:
https://doi.org/10.1021/..
?
15
Identification of Inhibitors of Checkpoint Kinase 1 through..:
Matthews, Thomas P.
;
Klair, Suki
;
Burns, Samantha
...
Journal of Medicinal Chemistry. 52 (2009) 15 - p. 4810-4819 , 2009
Link:
https://doi.org/10.1021/..
1-15