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Kharel, Yugesh
31
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1
Discovery of Potent, Orally Bioavailable Sphingosine-1-Phos..:
Foster, Daniel J.
;
Dunnavant, Kyle
;
Shrader, Christopher W.
...
Journal of Medicinal Chemistry. 67 (2024) 13 - p. 11273-11295 , 2024
Link:
https://doi.org/10.1021/..
?
2
Assay of Sphingosine 1-phosphate Transporter Spinster Homol..:
Kharel, Yugesh
;
Huang, Tao
;
Santos, Webster L.
.
SLAS Discovery. 28 (2023) 6 - p. 284-287 , 2023
Link:
https://doi.org/10.1016/..
?
3
2-Aminobenzoxazole Derivatives as Potent Inhibitors of the ..:
Burgio, Ariel L.
;
Shrader, Christopher W.
;
Kharel, Yugesh
...
Journal of Medicinal Chemistry. 66 (2023) 8 - p. 5873-5891 , 2023
Link:
https://doi.org/10.1021/..
?
4
Imidazole-based sphingosine-1-phosphate transporter Spns2 i..:
Shrader, Christopher W.
;
Foster, Daniel
;
Kharel, Yugesh
...
Bioorganic & Medicinal Chemistry Letters. 96 (2023) - p. 129516 , 2023
Link:
https://doi.org/10.1016/..
?
5
Sphingosine Kinase 2 Inhibitors: Rigid Aliphatic Tail Deriv..:
Pashikanti, Srinath
;
Foster, Daniel J.
;
Kharel, Yugesh
...
ACS Bio & Med Chem Au. 2 (2022) 5 - p. 469-489 , 2022
Link:
https://doi.org/10.1021/..
?
6
A Novel Sphingosine Kinase Inhibitor Suppresses Chikungunya..:
Oyewole, Opeoluwa O.
;
Dunnavant, Kyle
;
Bhattarai, Shaurav
...
Viruses. 14 (2022) 6 - p. 1123 , 2022
Link:
https://doi.org/10.3390/..
?
7
Discovery of In Vivo Active Sphingosine-1-phosphate Transpo..:
Fritzemeier, Russell
;
Foster, Daniel
;
Peralta, Ashley
...
Journal of Medicinal Chemistry. 65 (2022) 11 - p. 7656-7681 , 2022
Link:
https://doi.org/10.1021/..
?
8
Lipophilic tail modifications of 2-(hydroxymethyl)pyrrolidi..:
Li, Hao
;
Sibley, Christopher D.
;
Kharel, Yugesh
...
Bioorganic & Medicinal Chemistry. 30 (2021) - p. 115941 , 2021
Link:
https://doi.org/10.1016/..
?
9
Probing the substitution pattern of indole-based scaffold r..:
Congdon, Molly
;
Fritzemeier, Russell G.
;
Kharel, Yugesh
...
European Journal of Medicinal Chemistry. 212 (2021) - p. 113121 , 2021
Link:
https://doi.org/10.1016/..
?
10
Discovery of a Small Side Cavity in Sphingosine Kinase 2 th..:
Sibley, Christopher D.
;
Morris, Emily A.
;
Kharel, Yugesh
...
Journal of Medicinal Chemistry. 63 (2020) 3 - p. 1178-1198 , 2020
Link:
https://doi.org/10.1021/..
?
11
Mechanism of sphingosine 1-phosphate clearance from blood:
Kharel, Yugesh
;
Huang, Tao
;
Salamon, Anita
...
Biochemical Journal. 477 (2020) 5 - p. 925-935 , 2020
Link:
https://doi.org/10.1042/..
?
12
Photoacoustic microscopy reveals the hemodynamic basis of s..:
Cao, Rui
;
Li, Jun
;
Kharel, Yugesh
...
Theranostics. 8 (2018) 22 - p. 6111-6120 , 2018
Link:
https://doi.org/10.7150/..
?
13
Saccharomyces cerevisiae as a platform for assessing sphing..:
Kharel, Yugesh
;
Agah, Sayeh
;
Huang, Tao
...
PLOS ONE. 13 (2018) 4 - p. e0192179 , 2018
Link:
https://doi.org/10.1371/..
?
14
Transforming Sphingosine Kinase 1 Inhibitors into Dual and ..:
Childress, Elizabeth S.
;
Kharel, Yugesh
;
Brown, Anne M.
...
Journal of Medicinal Chemistry. 60 (2017) 9 - p. 3933-3957 , 2017
Link:
https://doi.org/10.1021/..
?
15
Structural Requirements and Docking Analysis of Amidine-Bas..:
Houck, Joseph D.
;
Dawson, Thomas K.
;
Kennedy, Andrew J.
...
ACS Medicinal Chemistry Letters. 7 (2016) 5 - p. 487-492 , 2016
Link:
https://doi.org/10.1021/..
1-15