Galetin, Aleksandra
79  results:
Search for persons X
?
1

Use of In Vivo Imaging and Physiologically-Based Kinetic Mo..:

Melillo, Nicola ; Scotcher, Daniel ; Kenna, J. Gerry...
Melillo , N , Scotcher , D , Kenna , J G , Green , C , Hines , C D G , Laitinen , I , Hockings , P D , Ogungbenro , K , Gunwhy , E R , Sourbron , S , Waterton , J C , Schuetz , G & Galetin , A 2023 , ' Use of In Vivo Imaging and Physiologically-Based Kinetic Modelling to Predict Hepatic Transporter Mediated Drug–Drug Interactions in Rats ' , Pharmaceutics , vol. 15 , no. 3 , 896 . https://doi.org/10.3390/pharmaceutics15030896.  , 2023
 
?
 
?
4

Development of 4-Pyridoxic Acid PBPK Model to Support Bioma..:

Tan, Shawn pei feng ; Willemin, Marie‐emilie ; Snoeys, Jan...
Tan , S P F , Willemin , M , Snoeys , J , Shen , H , Rostami‐hodjegan , A , Scotcher , D & Galetin , A 2023 , ' Development of 4-Pyridoxic Acid PBPK Model to Support Biomarker- Informed Evaluation of OAT1/3 Inhibition and Effect of Chronic Kidney Disease ' , Clinical Pharmacology & Therapeutics . https://doi.org/10.1002/cpt.3029.  , 2023
 
?
5

Effect of chronic kidney disease on the renal secretion via..:

Tan, Shawn Pei Feng ; Scotcher, Daniel ; Rostami‐hodjegan, Amin.
Tan , S P F , Scotcher , D , Rostami‐hodjegan , A & Galetin , A 2022 , ' Effect of chronic kidney disease on the renal secretion via organic anion transporters (OAT)1/3: Implications for PBPK modelling and dose adjustment ' , Clinical Pharmacology & Therapeutics . https://doi.org/10.1002/cpt.2642.  , 2022
 
?
6

Exploration and application of a liver-on-a-chip device in ..:

Docci, Luca ; Milani, Nicolò ; Ramp, Thomas...
Docci , L , Milani , N , Ramp , T , Romeo , A A , Godoy , P , Franyuti , D O , Krähenbühl , S , Gertz , M , Galetin , A , Parrott , N & Fowler , S 2022 , ' Exploration and application of a liver-on-a-chip device in combination with modelling and simulation for quantitative drug metabolism studies ' , Lab on a Chip , vol. 22 , no. 6 , pp. 1187-1205 . https://doi.org/10.1039/D1LC01161H.  , 2022
 
?
7

Clinical implications of altered drug transporter abundance..:

Chu, Xiaoyan ; Prasad, Bhagwat ; Neuhoff, Sibylle...
Chu , X , Prasad , B , Neuhoff , S , Yoshida , K , Leeder , J S , Mukherjee , D , Taskar , K , Varma , M V , Zhang , X , Yang , X & Galetin , A 2022 , ' Clinical implications of altered drug transporter abundance/function and PBPK modeling in specific populations: An ITC perspective ' , Clinical Pharmacology & Therapeutics . https://doi.org/10.1002/cpt.2643.  , 2022
 
?
8

Coproporphyrin I as an endogenous biomarker to detect reduc..:

Takita, Hiroyuki ; Scotcher, Daniel ; Chu, Xiaoyan...
Takita , H , Scotcher , D , Chu , X , Yee , K L , Ogungbenro , K & Galetin , A 2022 , ' Coproporphyrin I as an endogenous biomarker to detect reduced OATP1B activity and shift in elimination route in chronic kidney disease ' , Clinical Pharmacology & Therapeutics . https://doi.org/10.1002/cpt.2672.  , 2022
 
?
12

Population pharmacokinetic modeling and simulation to suppo..:

Ahmad, Amais ; Ogungbenro, Kayode ; Kunze, Annett...
Ahmad , A , Ogungbenro , K , Kunze , A , Jacobs , F , Snoeys , J , Rostami‐hodjegan , A & Galetin , A 2021 , ' Population pharmacokinetic modeling and simulation to support qualification of pyridoxic acid as endogenous biomarker of OAT1/3 renal transporters ' , CPT: Pharmacometrics and Systems Pharmacology , vol. 10 , no. 5 , pp. 467-477 . https://doi.org/10.1002/psp4.12610.  , 2021
 
?
13

PBPK Model of Coproporphyrin I: Evaluation of the Impact of..:

Takita, Hiroyuki ; Barnett, Shelby ; Zhang, Yueping...
Takita , H , Barnett , S , Zhang , Y , Ménochet , K , Shen , H , Ogungbenro , K & Galetin , A 2021 , ' PBPK Model of Coproporphyrin I: Evaluation of the Impact of SLCO1B1 Genotype, Ethnicity, and Sex on its Inter‐Individual Variability ' , CPT: Pharmacometrics and Systems Pharmacology . https://doi.org/10.1002/psp4.12582.  , 2021
 
?
14

Quantitative Proteomic Map of Enzymes and Transporters in t..:

Al-Majdoub, Zubida ; Scotcher, Daniel ; Achour, Brahim...
Al-Majdoub , Z , Scotcher , D , Achour , B , Barber , J , Galetin , A & Rostami-Hodjegan , A 2021 , ' Quantitative Proteomic Map of Enzymes and Transporters in the Human Kidney: Stepping Closer to Mechanistic Kidney Models to Define Local Kinetics ' , Clinical Pharmacology & Therapeutics , vol. 110 , no. 5 , pp. 1389-1400 . https://doi.org/10.1002/cpt.2396.  , 2021
 
?
15

Model-based drug-drug interaction extrapolation strategy fr..:

Fukushima (Cleary), Yumi ; Gertz, Michael ; Grimsey, Paul...
Fukushima (Cleary) , Y , Gertz , M , Grimsey , P , Günther , A , Heinig , K , Ogungbenro , K , Aarons , L , Galetin , A & Kletzl , H 2021 , ' Model-based drug-drug interaction extrapolation strategy from adults to children – risdiplam in pediatric patients with spinal muscular atrophy ' , Clinical Pharmacology & Therapeutics . https://doi.org/10.1002/cpt.2384.  , 2021
 
1-15