Martínek, Václav
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2

Identification of human enzymes oxidizing the anti-thyroid-..:

Indra, Radek ; Pompach, Petr ; Martínek, Václav...
Indra , R , Pompach , P , Martínek , V , Takácsová , P , Vavrová , K , Heger , Z , Adam , V , Eckschlager , T , Kopečková , K , Arlt , V M & Stiborová , M 2019 , ' Identification of human enzymes oxidizing the anti-thyroid-cancer drug Vandetanib and explanation of the high efficiency of cytochrome P450 3A4 in its oxidation ' , International Journal of Molecular Sciences , vol. 20 , no. 14 , 3392 . https://doi.org/10.3390/ijms20143392.  , 2019
 
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Identification of human enzymes oxidizing the anti-thyroid-..:

Indra, Radek ; Pompach, Petr ; Martínek, Václav...
Indra , R , Pompach , P , Martínek , V , Takácsová , P , Vavrová , K , Heger , Z , Adam , V , Eckschlager , T , Kopečková , K , Arlt , V M & Stiborová , M 2019 , ' Identification of human enzymes oxidizing the anti-thyroid-cancer drug Vandetanib and explanation of the high efficiency of cytochrome P450 3A4 in its oxidation ' , International Journal of Molecular Sciences , vol. 20 , no. 14 , 3392 . https://doi.org/10.3390/ijms20143392.  , 2019
 
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Comparison of the oxidation of carcinogenic aristolochic ac..:

Martínek, Václav ; Bárta, František ; Hodek, Petr...
Martínek , V , Bárta , F , Hodek , P , Frei , E , Schmeiser , H H , Arlt , V M & Stiborová , M 2017 , ' Comparison of the oxidation of carcinogenic aristolochic acid I and II by microsomal cytochromes P450 in vitro : experimental and theoretical approaches ' , Monatshefte für Chemie - Chemical Monthly , vol. 148 , no. 11 , pp. 1971-1981 . https://doi.org/10.1007/s00706-017-2014-9.  , 2017
 
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Comparison of the oxidation of carcinogenic aristolochic ac..:

Martínek, Václav ; Bárta, František ; Hodek, Petr...
Martínek , V , Bárta , F , Hodek , P , Frei , E , Schmeiser , H H , Arlt , V M & Stiborová , M 2017 , ' Comparison of the oxidation of carcinogenic aristolochic acid I and II by microsomal cytochromes P450 in vitro : experimental and theoretical approaches ' , Monatshefte für Chemie - Chemical Monthly , vol. 148 , no. 11 , pp. 1971-1981 . https://doi.org/10.1007/s00706-017-2014-9.  , 2017
 
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Cytochrome b 5 plays a dual role in the reaction cycle of c..:

Stiborová, Marie ; Indra, Radek ; Frei, Eva...
Stiborová , M , Indra , R , Frei , E , Kopečková , K , Schmeiser , H H , Eckschlager , T , Adam , V , Heger , Z , Arlt , V M & Martínek , V 2017 , ' Cytochrome b 5 plays a dual role in the reaction cycle of cytochrome P450 3A4 during oxidation of the anticancer drug ellipticine ' , Monatshefte für Chemie - Chemical Monthly , vol. 148 , no. 11 , pp. 1983-1991 . https://doi.org/10.1007/s00706-017-1986-9.  , 2017
 
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Cytochrome b 5 plays a dual role in the reaction cycle of c..:

Stiborová, Marie ; Indra, Radek ; Frei, Eva...
Stiborová , M , Indra , R , Frei , E , Kopečková , K , Schmeiser , H H , Eckschlager , T , Adam , V , Heger , Z , Arlt , V M & Martínek , V 2017 , ' Cytochrome b 5 plays a dual role in the reaction cycle of cytochrome P450 3A4 during oxidation of the anticancer drug ellipticine ' , Monatshefte für Chemie - Chemical Monthly , vol. 148 , no. 11 , pp. 1983-1991 . https://doi.org/10.1007/s00706-017-1986-9.  , 2017
 
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Active site mutations as a suitable tool contributing to ex..:

Milichovký, Jan ; Bárta, František ; Schmeiser, Heinz H...
Milichovký , J , Bárta , F , Schmeiser , H H , Arlt , V , Frei , E , Stiborová , M & Martínek , V 2016 , ' Active site mutations as a suitable tool contributing to explain a mechanism of aristolochic acid I nitroreduction by cytochromes P450 1A1, 1A2 and 1B1 ' , International Journal of Molecular Sciences , vol. 17 , no. 2 . https://doi.org/10.3390/ijms17020213.  , 2016
 
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Active site mutations as a suitable tool contributing to ex..:

Milichovký, Jan ; Bárta, František ; Schmeiser, Heinz H...
Milichovký , J , Bárta , F , Schmeiser , H H , Arlt , V , Frei , E , Stiborová , M & Martínek , V 2016 , ' Active site mutations as a suitable tool contributing to explain a mechanism of aristolochic acid I nitroreduction by cytochromes P450 1A1, 1A2 and 1B1 ' , International Journal of Molecular Sciences , vol. 17 , no. 2 . https://doi.org/10.3390/ijms17020213.  , 2016
 
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Highly conserved nucleotide phosphatase essential for membr..:

Kuipers, Kirsten ; Gallay, Clement ; Martínek, Václav...
Highly conserved nucleotide phosphatase essential for membrane lipid homeostasis in Streptococcus pneumoniae. 2016, 101 (1):12-26 Mol. Microbiol..  , 2016
 
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Induced expression of microsomal cytochrome b 5 determined ..:

Stiborová, Marie ; Moserová, Michaela ; Mrízová, Iveta...
Stiborová , M , Moserová , M , Mrízová , I , Dračínská , H , Martínek , V , Indra , R , Frei , E , Adam , V , Kizek , R , Schmeiser , H H , Kubáčková , K & Arlt , V M 2016 , ' Induced expression of microsomal cytochrome b 5 determined at mRNA and protein levels in rats exposed to ellipticine, benzo[a]pyrene, and 1-phenylazo-2-naphthol (Sudan I) ' , Monatshefte für Chemie - Chemical Monthly , vol. 147 , pp. 897-904 . https://doi.org/10.1007/s00706-015-1636-z.  , 2016
 
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