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Akama, Tsutomu
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1

Discovery of an orally active benzoxaborole prodrug effecti..:

Padilla, Angel M. ; Wang, Wei ; Akama, Tsutomu...
Nature Microbiology.  7 (2022)  10 - p. 1536-1546 , 2022
Link: https://doi.org/10.1038/..
 
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2

Macrofilaricidal Benzimidazole–Benzoxaborole Hybrids as an ..:

Akama, Tsutomu ; Freund, Yvonne R. ; Berry, Pamela W....
ACS Infectious Diseases.  6 (2019)  2 - p. 173-179 , 2019
Link: https://doi.org/10.1021/..
 
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3

Macrofilaricidal Benzimidazole–Benzoxaborole Hybrids as an ..:

Carter, David S. ; Jacobs, Robert T. ; Freund, Yvonne R....
ACS Infectious Diseases.  6 (2019)  2 - p. 180-185 , 2019
Link: https://doi.org/10.1021/..
 
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4

Identification of a 4-fluorobenzyl l-valinate amide benzoxa..:

Akama, Tsutomu ; Zhang, Yong-Kang ; Freund, Yvonne R....
Bioorganic & Medicinal Chemistry Letters.  28 (2018)  1 - p. 6-10 , 2018
Link: https://doi.org/10.1016/..
 
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5

Optimization of isoxazoline amide benzoxaboroles for identi..:

Zhang, Yong-Kang ; Plattner, Jacob J. ; Easom, Eric E....
Bioorganic & Medicinal Chemistry Letters.  26 (2016)  13 - p. 3182-3186 , 2016
Link: https://doi.org/10.1016/..
 
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6

Discovery of an orally bioavailable isoxazoline benzoxaboro..:

Zhang, Yong-Kang ; Plattner, Jacob J. ; Easom, Eric E....
Bioorganic & Medicinal Chemistry Letters.  25 (2015)  23 - p. 5589-5593 , 2015
Link: https://doi.org/10.1016/..
 
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7

Structure–activity relationships of 6-(aminomethylphenoxy)-..:

Akama, Tsutomu ; Virtucio, Charlotte ; Dong, Chen...
Bioorganic & Medicinal Chemistry Letters.  23 (2013)  6 - p. 1680-1683 , 2013
Link: https://doi.org/10.1016/..
 
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8

Discovery and structure–activity relationships of 6-(benzoy..:

Akama, Tsutomu ; Dong, Chen ; Virtucio, Charlotte...
Bioorganic & Medicinal Chemistry Letters.  23 (2013)  21 - p. 5870-5873 , 2013
Link: https://doi.org/10.1016/..
 
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9

Boron‐based phosphodiesterase inhibitors show novel binding..:

Freund, Yvonne R. ; Akama, Tsutomu ; Alley, M.R.K....
FEBS Letters.  586 (2012)  19 - p. 3410-3414 , 2012
Link: https://doi.org/10.1016/..
 
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10

Early rapid identification of in vivo rat metabolites of AN..:

Bu, Wei ; Akama, Tsutomu ; Chanda, Sanjay...
Journal of Pharmaceutical and Biomedical Analysis.  70 (2012)  - p. 344-353 , 2012
Link: https://doi.org/10.1016/..
 
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11

SCYX-7158, an Orally-Active Benzoxaborole for the Treatment..:

Jacobs, Robert T. ; Nare, Bakela ; Wring, Stephen A....
PLoS Neglected Tropical Diseases.  5 (2011)  6 - p. e1151 , 2011
Link: https://doi.org/10.1371/..
 
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12

Design and synthesis of boron-containing PDE4 inhibitors us..:

Zhang, Yong-Kang ; Plattner, Jacob J. ; Akama, Tsutomu...
Bioorganic & Medicinal Chemistry Letters.  20 (2010)  7 - p. 2270-2274 , 2010
Link: https://doi.org/10.1016/..
 
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13

Discovery and structure–activity study of a novel benzoxabo..:

Akama, Tsutomu ; Baker, Stephen J. ; Zhang, Yong-Kang...
Bioorganic & Medicinal Chemistry Letters.  19 (2009)  8 - p. 2129-2132 , 2009
Link: https://doi.org/10.1016/..
 
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14

An Antifungal Agent Inhibits an Aminoacyl-tRNA Synthetase b..:

Rock, Fernando L. ; Mao, Weimin ; Yaremchuk, Anya...
Science.  316 (2007)  5832 - p. 1759-1761 , 2007
Link: https://doi.org/10.1126/..
 
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15

In Vitro Penetration of a Novel Oxaborole Antifungal (AN269..:

Hui, Xiaoying ; Baker, Stephen J. ; Wester, Ronald C....
Journal of Pharmaceutical Sciences.  96 (2007)  10 - p. 2622-2631 , 2007
Link: https://doi.org/10.1002/..
 
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