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Appleton, Brent A.
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1

Design and Discovery of N-(3-(2-(2-Hydroxyethoxy)-6-morphol..:

Ramurthy, Savithri ; Taft, Benjamin R. ; Aversa, Robert J....
Journal of Medicinal Chemistry.  63 (2019)  5 - p. 2013-2027 , 2019
Link: https://doi.org/10.1021/..
 
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2

Fragment-Based Drug Discovery of Inhibitors of Phosphopante..:

Moreau, Robert J. ; Skepper, Colin K. ; Appleton, Brent A....
Journal of Medicinal Chemistry.  61 (2018)  8 - p. 3309-3324 , 2018
Link: https://doi.org/10.1021/..
 
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3

Design and synthesis of potent RSK inhibitors:

Jain, Rama ; Mathur, Michelle ; Lan, Jiong...
Bioorganic & Medicinal Chemistry Letters.  28 (2018)  19 - p. 3197-3201 , 2018
Link: https://doi.org/10.1016/..
 
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4

Discovery and Optimization of Phosphopantetheine Adenylyltr..:

Skepper, Colin K. ; Moreau, Robert J. ; Appleton, Brent A....
Journal of Medicinal Chemistry.  61 (2018)  8 - p. 3325-3349 , 2018
Link: https://doi.org/10.1021/..
 
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5

Mathematical and Structural Characterization of Strong Nona..:

Gomez, Laurent ; Xu, Rui ; Sinko, William...
Journal of Medicinal Chemistry.  61 (2018)  17 - p. 7754-7766 , 2018
Link: https://doi.org/10.1021/..
 
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6

Design and Discovery of N-(2-Methyl-5′-morpholino-6′-((tetr..:

Nishiguchi, Gisele A. ; Rico, Alice ; Tanner, Huw...
Journal of Medicinal Chemistry.  60 (2017)  12 - p. 4869-4881 , 2017
Link: https://doi.org/10.1021/..
 
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7

Imidazo[1,2- a ]pyridin-6-yl-benzamide analogs as potent RA..:

Smith, Aaron ; Ni, Zhi-Jie ; Poon, Daniel...
Bioorganic & Medicinal Chemistry Letters.  27 (2017)  23 - p. 5221-5224 , 2017
Link: https://doi.org/10.1016/..
 
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8

Discovery of a Selective and Potent Inhibitor of Mitogen-Ac..:

Han, Wooseok ; Ding, Yu ; Xu, Yongjin...
Journal of Medicinal Chemistry.  59 (2016)  7 - p. 3034-3045 , 2016
Link: https://doi.org/10.1021/..
 
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9

Discovery of RAF265: A Potent mut-B-RAF Inhibitor for the T..:

Williams, Teresa E. ; Subramanian, Sharadha ; Verhagen, Joelle...
ACS Medicinal Chemistry Letters.  6 (2015)  9 - p. 961-965 , 2015
Link: https://doi.org/10.1021/..
 
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10

Discovery of Potent and Selective RSK Inhibitors as Biologi..:

Jain, Rama ; Mathur, Michelle ; Lan, Jiong...
Journal of Medicinal Chemistry.  58 (2015)  17 - p. 6766-6783 , 2015
Link: https://doi.org/10.1021/..
 
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11

A Structural Portrait of the PDZ Domain Family:

Ernst, Andreas ; Appleton, Brent A. ; Ivarsson, Ylva...
Journal of Molecular Biology.  426 (2014)  21 - p. 3509-3519 , 2014
Link: https://doi.org/10.1016/..
 
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12

2-Amino-7-substituted benzoxazole analogs as potent RSK2 in..:

Costales, Abran ; Mathur, Michelle ; Ramurthy, Savithri...
Bioorganic & Medicinal Chemistry Letters.  24 (2014)  6 - p. 1592-1596 , 2014
Link: https://doi.org/10.1016/..
 
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13

Discovery of the 1,7-diazacarbazole class of inhibitors of ..:

Gazzard, Lewis ; Appleton, Brent ; Chapman, Kerry...
Bioorganic & Medicinal Chemistry Letters.  24 (2014)  24 - p. 5704-5709 , 2014
Link: https://doi.org/10.1016/..
 
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14

Structure of IL-33 and Its Interaction with the ST2 and IL-..:

Lingel, Andreas ; Weiss, Thomas M. ; Niebuhr, Marc...
Structure.  17 (2009)  10 - p. 1398-1410 , 2009
Link: https://doi.org/10.1016/..
 
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15

Variants of the Antibody Herceptin That Interact with HER2 ..:

Bostrom, Jenny ; Yu, Shang-Fan ; Kan, David...
Science.  323 (2009)  5921 - p. 1610-1614 , 2009
Link: https://doi.org/10.1126/..
 
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