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Astles, Peter C.
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1

Discovery of a Series of Orally Bioavailable Androgen Recep..:

Bagal, Sharan K. ; Astles, Peter C. ; Diène, Coura...
Journal of Medicinal Chemistry.  , 2024
Link: https://doi.org/10.1021/..
 
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2

Identification of Novel Potent NSD2-PWWP1 Ligands Using Str..:

Carlino, Luca ; Astles, Peter C. ; Ackroyd, Bryony...
Journal of Medicinal Chemistry.  67 (2024)  11 - p. 8962-8987 , 2024
Link: https://doi.org/10.1021/..
 
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3

Unique pharmacology of heteromeric α7β2 nicotinic acetylcho..:

Zwart, Ruud ; Strotton, Merrick ; Ching, Jennifer..
European Journal of Pharmacology.  726 (2014)  - p. 77-86 , 2014
Link: https://doi.org/10.1016/..
 
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4

The SAR development of substituted purine derivatives as se..:

Guidetti, Rossella ; Astles, Peter C. ; Sanderson, Adam J....
Bioorganic & Medicinal Chemistry Letters.  24 (2014)  24 - p. 5572-5575 , 2014
Link: https://doi.org/10.1016/..
 
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5

Selective Cannabinoid Receptor Type 2 (CB2) Agonists: Optim..:

Hollinshead, Sean P. ; Tidwell, Michael W. ; Palmer, John...
Journal of Medicinal Chemistry.  56 (2013)  14 - p. 5722-5733 , 2013
Link: https://doi.org/10.1021/..
 
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6

Discovery and optimization of novel purines as potent and s..:

Hollinshead, Sean P. ; Astles, Peter C. ; Chambers, Mark G....
Bioorganic & Medicinal Chemistry Letters.  22 (2012)  15 - p. 4962-4966 , 2012
Link: https://doi.org/10.1016/..
 
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7

Total Synthesis of (±)-α-Isosparteine, (±)-β-Isosparteine, ..:

Norcross, Neil R. ; Melbardis, John P. ; Solera, Margarita Ferris...
The Journal of Organic Chemistry.  73 (2008)  20 - p. 7939-7951 , 2008
Link: https://doi.org/10.1021/..
 
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8

A Practical Synthesis of (±)-α-Isosparteine from a Tetraoxo..:

Blakemore, Paul R. ; Kilner, Colin ; Norcross, Neil R..
Organic Letters.  7 (2005)  21 - p. 4721-4724 , 2005
Link: https://doi.org/10.1021/..
 
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9

Anti-inflammatory modulators in stroke:

O'Neill, Michael J. ; Astles, Peter C. ; Allan, Stuart M..
Drug Discovery Today: Therapeutic Strategies.  1 (2004)  1 - p. 59-67 , 2004
Link: https://doi.org/10.1016/..
 
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10

Diamine containing VLA-4 antagonists:

Astles, Peter C. ; Harris, Neil V. ; Morley, Andrew D.
Bioorganic & Medicinal Chemistry.  9 (2001)  8 - p. 2195-2202 , 2001
Link: https://doi.org/10.1016/..
 
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11

Selective ETAAntagonists. 5. Discovery and Structure−Activi..:

Astles, Peter C. ; Brown, Thomas J. ; Halley, Frank...
Journal of Medicinal Chemistry.  43 (2000)  5 - p. 900-910 , 2000
Link: https://doi.org/10.1021/..
 
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12

Selective Endothelin A Receptor Antagonists. 4. Discovery a..:

Astles, Peter C. ; Brown, Thomas J. ; Halley, Frank...
Journal of Medicinal Chemistry.  41 (1998)  15 - p. 2745-2753 , 1998
Link: https://doi.org/10.1021/..
 
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13

Selective Endothelin A Receptor Antagonists. 3. Discovery a..:

Astles, Peter C. ; Brealey, Clive ; Brown, Thomas J....
Journal of Medicinal Chemistry.  41 (1998)  15 - p. 2732-2744 , 1998
Link: https://doi.org/10.1021/..
 
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14

New non peptidic C5a receptor antagonists:

Astles, Peter C. ; Brown, Thomas J. ; Cox, Paul...
Bioorganic & Medicinal Chemistry Letters.  7 (1997)  7 - p. 907-912 , 1997
Link: https://doi.org/10.1016/..
 
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15

Acyl-CoA:CholesterolO-Acyltransferase (ACAT) Inhibitors. 2...:

Astles, Peter C. ; Ashton, Michael J. ; Bridge, Andrew W....
Journal of Medicinal Chemistry.  39 (1996)  7 - p. 1423-1432 , 1996
Link: https://doi.org/10.1021/..
 
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