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Babusis, Darius
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1

Oral administration of obeldesivir protects nonhuman primat..:

Cross, Robert W. ; Woolsey, Courtney ; Chu, Victor C....
Science.  383 (2024)  6688 - p. , 2024
Link: https://doi.org/10.1126/..
 
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2

Discovery of GS-5245 (Obeldesivir), an Oral Prodrug of Nucl..:

Mackman, Richard L. ; Kalla, Rao V. ; Babusis, Darius...
Journal of Medicinal Chemistry.  66 (2023)  17 - p. 11701-11717 , 2023
Link: https://doi.org/10.1021/..
 
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3

539. Efficacy in Multiple SARS-CoV-2 Animal Models Supports..:

Pitts, Jared ; Babusis, Darius ; Humeniuk, Rita...
Open Forum Infectious Diseases.  10 (2023)  Supplement_2 - p. , 2023
Link: https://doi.org/10.1093/..
 
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4

Characterization of the Cynomolgus Macaque Model of Marburg..:

Zumbrun, Elizabeth E. ; Garvey, Carly B. ; Wells, Jay B....
Viruses.  15 (2023)  12 - p. 2335 , 2023
Link: https://doi.org/10.3390/..
 
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5

The Nucleoside/Nucleotide Analogs Tenofovir and Emtricitabi..:

Feng, Joy Y. ; Du Pont, Venice ; Babusis, Darius...
Molecules.  27 (2022)  13 - p. 4212 , 2022
Link: https://doi.org/10.3390/..
 
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6

Subcutaneous remdesivir administration prevents interstitia..:

Williamson, Brandi N. ; Pérez-Pérez, Lizzette ; Schwarz, Benjamin...
Antiviral Research.  198 (2022)  - p. 105246 , 2022
Link: https://doi.org/10.1016/..
 
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7

Intravenous delivery of GS-441524 is efficacious in the Afr..:

Pitts, Jared ; Babusis, Darius ; Vermillion, Meghan S....
Antiviral Research.  203 (2022)  - p. 105329 , 2022
Link: https://doi.org/10.1016/..
 
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8

Pharmacokinetic, Pharmacodynamic, and Drug-Interaction Prof..:

Humeniuk, Rita ; Mathias, Anita ; Kirby, Brian J....
Clinical Pharmacokinetics.  60 (2021)  5 - p. 569-583 , 2021
Link: https://doi.org/10.1007/..
 
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9

Off-TargetIn VitroProfiling Demonstrates that Remdesivir Is..:

Xu, Yili ; Barauskas, Ona ; Kim, Cynthia...
Antimicrobial Agents and Chemotherapy.  65 (2021)  2 - p. , 2021
Link: https://doi.org/10.1128/..
 
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10

Oral prodrug of remdesivir parent GS-441524 is efficacious ..:

Cox, Robert M. ; Wolf, Josef D. ; Lieber, Carolin M....
Nature Communications.  12 (2021)  1 - p. , 2021
Link: https://doi.org/10.1038/..
 
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11

Key Metabolic Enzymes Involved in Remdesivir Activation in ..:

Li, Ruidong ; Liclican, Albert ; Xu, Yili...
Antimicrobial Agents and Chemotherapy.  65 (2021)  9 - p. , 2021
Link: https://doi.org/10.1128/..
 
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12

Prodrugs of a 1′-CN-4-Aza-7,9-dideazaadenosine C-Nucleoside..:

Mackman, Richard L. ; Hui, Hon C. ; Perron, Michel...
Journal of Medicinal Chemistry.  64 (2021)  8 - p. 5001-5017 , 2021
Link: https://doi.org/10.1021/..
 
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13

Remdesivir Inhibits SARS-CoV-2 in Human Lung Cells and Chim..:

Pruijssers, Andrea J. ; George, Amelia S. ; Schäfer, Alexandra...
Cell Reports.  32 (2020)  3 - p. 107940 , 2020
Link: https://doi.org/10.1016/..
 
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14

Comparative therapeutic efficacy of remdesivir and combinat..:

Sheahan, Timothy P. ; Sims, Amy C. ; Leist, Sarah R....
Nature Communications.  11 (2020)  1 - p. , 2020
Link: https://doi.org/10.1038/..
 
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15

Two-dose emtricitabine/tenofovir alafenamide plus bictegrav..:

Bekerman, Elena ; Cox, Stephanie ; Babusis, Darius...
Journal of Antimicrobial Chemotherapy.  76 (2020)  3 - p. 692-698 , 2020
Link: https://doi.org/10.1093/..
 
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