E-LIB Suche - Ergebnisse für: Baer, Brian R.

1

Identification of the Clinical Candidate PF-07284890 (ARRY-..:

Ren, Li ; Moreno, David ; Baer, Brian R....
Journal of Medicinal Chemistry. 67 (2024) 15 - p. 13019-13032 , 2024

Link: https://doi.org/10.1021/..

2

A next-generation BRAF inhibitor overcomes resistance to BR..:

Yaeger, Rona ; McKean, Meredith A. ; Haq, Rizwan...
Cancer Discovery. , 2024

Link: https://doi.org/10.1158/..

3

Discovery and preclinical development of AR453588 as an ant..:

Hinklin, Ronald J. ; Baer, Brian R. ; Boyd, Steven A....
Bioorganic & Medicinal Chemistry. 28 (2020) 1 - p. 115232 , 2020

Link: https://doi.org/10.1016/..

4

Identification of the Clinical Development Candidate MRTX84..:

Fell, Jay B. ; Fischer, John P. ; Baer, Brian R....
Journal of Medicinal Chemistry. 63 (2020) 13 - p. 6679-6693 , 2020

Link: https://doi.org/10.1021/..

5

Discovery of Tetrahydropyridopyrimidines as Irreversible Co..:

Fell, Jay B. ; Fischer, John P. ; Baer, Brian R....
ACS Medicinal Chemistry Letters. 9 (2018) 12 - p. 1230-1234 , 2018

Link: https://doi.org/10.1021/..

6

The Crystal Structure of Cytochrome P450 4B1 (CYP4B1) Monoo..:

Hsu, Mei-Hui ; Baer, Brian R. ; Rettie, Allan E..
Journal of Biological Chemistry. 292 (2017) 13 - p. 5610-5621 , 2017

Link: https://doi.org/10.1074/..

7

C5-Alkyl-2-methylurea-Substituted Pyridines as a New Class ..:

Du, Xiaohui ; Hinklin, Ronald J. ; Xiong, Yumei...
ACS Medicinal Chemistry Letters. 5 (2014) 12 - p. 1284-1289 , 2014

Link: https://doi.org/10.1021/..

8

Discovery of 2-Pyridylureas as Glucokinase Activators:

Hinklin, Ronald J. ; Aicher, Thomas D. ; Anderson, Deborah A....
Journal of Medicinal Chemistry. 57 (2014) 19 - p. 8180-8186 , 2014

Link: https://doi.org/10.1021/..

9

Characterization of a Novel Glucokinase Activator in Rat an..:

Lu, Min ; Li, Pingping ; Bandyopadhyay, Gautam...
PLoS ONE. 9 (2014) 2 - p. e88431 , 2014

Link: https://doi.org/10.1371/..

10

Benzylic Oxidation of Gemfibrozil-1-O-β-Glucuronide by P450..:

Baer, Brian R. ; DeLisle, Robert Kirk ; Allen, Andrew
Chemical Research in Toxicology. 22 (2009) 7 - p. 1298-1309 , 2009

Link: https://doi.org/10.1021/..

11

Mechanism of Formation of the Ester Linkage between Heme an..:

Baer, Brian R. ; Kunze, Kent L. ; Rettie, Allan E.
Biochemistry. 46 (2007) 41 - p. 11598-11605 , 2007

Link: https://doi.org/10.1021/..

12

Time-Dependent Inactivation of P450 3A4 by Raloxifene: Ide..:

Baer, Brian R. ; Wienkers, Larry C. ; Rock, Dan A.
Chemical Research in Toxicology. 20 (2007) 6 - p. 954-964 , 2007

Link: https://doi.org/10.1021/..

13

Bioactivation of 4-Ipomeanol by CYP4B1: Adduct Characteriz..:

Baer, Brian R. ; Rettie, Allan E. ; Henne, Kirk R.
Chemical Research in Toxicology. 18 (2005) 5 - p. 855-864 , 2005

Link: https://doi.org/10.1021/..

14

Sites of Covalent Attachment of CYP4 Enzymes to Heme: Evid..:

Baer, Brian R. ; Schuman, Jason T. ; Campbell, A. Patricia...
Biochemistry. 44 (2005) 42 - p. 13914-13920 , 2005

Link: https://doi.org/10.1021/..

15

Rabbit CYP4B1 engineered for high-level expression in Esche..:

Cheesman, Matthew J ; Baer, Brian R ; Zheng, Yi-Min..
Archives of Biochemistry and Biophysics. 416 (2003) 1 - p. 17-24 , 2003

Link: https://doi.org/10.1016/..