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Bihan, Yann-Vaï Le
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1

iTAG an optimized IMiD-induced degron for targeted protein ..:

Bouguenina, Habib ; Nicolaou, Stephanos ; Bihan, Yann-Vaï Le...
iScience.  27 (2024)  5 - p. 109727 , 2024
Link: https://doi.org/10.1016/..
 
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2

iTAG an optimized IMiD-induced degron for targeted protein ..:

Bouguenina, Habib ; Nicolaou, Stephanos ; Le Bihan, Yann-Vaï...
iScience.  26 (2023)  7 - p. 107059 , 2023
Link: https://doi.org/10.1016/..
 
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3

Discovery of an In Vivo Chemical Probe for BCL6 Inhibition ..:

Harnden, Alice C. ; Davis, Owen A. ; Box, Gary M....
Journal of Medicinal Chemistry.  66 (2023)  8 - p. 5892-5906 , 2023
Link: https://doi.org/10.1021/..
 
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4

Improved Binding Affinity and Pharmacokinetics Enable Susta..:

Huckvale, Rosemary ; Harnden, Alice C. ; Cheung, Kwai-Ming J....
Journal of Medicinal Chemistry.  65 (2022)  12 - p. 8191-8207 , 2022
Link: https://doi.org/10.1021/..
 
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5

Discovering cell-active BCL6 inhibitors: effectively combin..:

Pierrat, Olivier A. ; Liu, Manjuan ; Collie, Gavin W....
Scientific Reports.  12 (2022)  1 - p. , 2022
Link: https://doi.org/10.1038/..
 
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6

Optimizing Shape Complementarity Enables the Discovery of P..:

Davis, Owen A. ; Cheung, Kwai-Ming J. ; Brennan, Alfie...
Journal of Medicinal Chemistry.  65 (2022)  12 - p. 8169-8190 , 2022
Link: https://doi.org/10.1021/..
 
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7

Discovery and Characterization of a Cryptic Secondary Bindi..:

O'Connor, Suzanne ; Le Bihan, Yann-Vaï ; Westwood, Isaac M....
Molecules.  27 (2022)  3 - p. 817 , 2022
Link: https://doi.org/10.3390/..
 
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8

Into Deep Water: Optimizing BCL6 Inhibitors by Growing into..:

Lloyd, Matthew G. ; Huckvale, Rosemary ; Cheung, Kwai-Ming J....
Journal of Medicinal Chemistry.  64 (2021)  23 - p. 17079-17097 , 2021
Link: https://doi.org/10.1021/..
 
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9

Achieving In Vivo Target Depletion through the Discovery an..:

Bellenie, Benjamin R. ; Cheung, Kwai-Ming J. ; Varela, Ana...
Journal of Medicinal Chemistry.  63 (2020)  8 - p. 4047-4068 , 2020
Link: https://doi.org/10.1021/..
 
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10

Structural and functional characterisation of human RNA hel..:

Felisberto-Rodrigues, Catarina ; Thomas, Jemima C. ; McAndrew, Craig...
Biochemical Journal.  476 (2019)  18 - p. 2521-2543 , 2019
Link: https://doi.org/10.1042/..
 
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11

C8-substituted pyrido[3,4-d]pyrimidin-4(3H)-ones: Studies t..:

Le Bihan, Yann-Vaï ; Lanigan, Rachel M. ; Atrash, Butrus...
European Journal of Medicinal Chemistry.  177 (2019)  - p. 316-337 , 2019
Link: https://doi.org/10.1016/..
 
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12

Privileged Structures and Polypharmacology within and betwe..:

Meyers, Joshua ; Chessum, Nicola E. A. ; Ali, Salyha...
ACS Medicinal Chemistry Letters.  9 (2018)  12 - p. 1199-1204 , 2018
Link: https://doi.org/10.1021/..
 
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13

Pyrido[3,4-d]pyrimidin-4(3H)-one metabolism mediated by ald..:

Hayes, Angela ; Mok, N. Yi ; Liu, Manjuan...
Xenobiotica.  47 (2016)  9 - p. 771-777 , 2016
Link: https://doi.org/10.1080/..
 
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14

8-Substituted Pyrido[3,4-d]pyrimidin-4(3H)-one Derivatives ..:

Bavetsias, Vassilios ; Lanigan, Rachel M. ; Ruda, Gian Filippo...
Journal of Medicinal Chemistry.  59 (2016)  4 - p. 1388-1409 , 2016
Link: https://doi.org/10.1021/..
 
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15

A higher-order entity formed by the flexible assembly of RA..:

Gaullier, Guillaume ; Miron, Simona ; Pisano, Sabrina...
Nucleic Acids Research.  44 (2016)  4 - p. 1962-1976 , 2016
Link: https://doi.org/10.1093/..
 
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