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Botham, Rachel C.
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1

Optimizing human α-galactosidase for treatment of Fabry dis..:

Hallows, William C. ; Skvorak, Kristen ; Agard, Nick...
Scientific Reports.  13 (2023)  1 - p. , 2023
Link: https://doi.org/10.1038/..
 
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2

Engineering α-glucosidase to improve protein stability and ..:

Botham, Rachel C. ; Hallows, William C. ; Reddy, Charu...
Molecular Genetics and Metabolism.  132 (2021)  2 - p. S20-S21 , 2021
Link: https://doi.org/10.1016/..
 
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3

Evaluation of a procaspase-3 activator with hydroxyurea or ..:

Tonogai, Emily J ; Huang, Shan ; Botham, Rachel C...
Neuro-Oncology.  23 (2021)  10 - p. 1723-1735 , 2021
Link: https://doi.org/10.1093/..
 
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4

Adapting protein sequences for optimized therapeutic effica..:

Dellas, Nikki ; Liu, Joyce ; Botham, Rachel C..
Current Opinion in Chemical Biology.  64 (2021)  - p. 38-47 , 2021
Link: https://doi.org/10.1016/..
 
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5

Synergistic and targeted therapy with a procaspase-3 activa..:

Joshi, Avadhut D. ; Botham, Rachel C. ; Schlein, Lisa J....
Oncotarget.  8 (2017)  46 - p. 80124-80138 , 2017
Link: https://doi.org/10.18632..
 
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6

A Small Molecule that Induces Intrinsic Pathway Apoptosis w..:

Palchaudhuri, Rahul ; Lambrecht, Michael J. ; Botham, Rachel C....
Cell Reports.  13 (2015)  9 - p. 2027-2036 , 2015
Link: https://doi.org/10.1016/..
 
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7

Removal of Metabolic Liabilities Enables Development of Der..:

Roth, Howard S. ; Botham, Rachel C. ; Schmid, Steven C....
Journal of Medicinal Chemistry.  58 (2015)  9 - p. 4046-4065 , 2015
Link: https://doi.org/10.1021/..
 
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8

Dual Small-Molecule Targeting of Procaspase-3 Dramatically ..:

Botham, Rachel C. ; Fan, Timothy M. ; Im, Isak...
Journal of the American Chemical Society.  136 (2014)  4 - p. 1312-1319 , 2014
Link: https://doi.org/10.1021/..
 
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9

Parallel Synthesis and Biological Evaluation of 837 Analogu..:

Hsu, Danny C. ; Roth, Howard S. ; West, Diana C....
ACS Combinatorial Science.  14 (2011)  1 - p. 44-50 , 2011
Link: https://doi.org/10.1021/..
 
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10

Direct procaspase activation as a therapeutic strategy in t..:

Peterson, Quinn P ; West, Diana C. ; Hsu, Danny C....
The FASEB Journal.  24 (2010)  S1 - p. , 2010
Link: https://doi.org/10.1096/..
 
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11

Using sulfuramidimidoyl fluorides that undergo sulfur(VI) f..:

Brighty, Gabriel J ; Botham, Rachel C ; Li, Suhua...
qt9mw7b5sv.  , 2020
Link: https://escholarship.org..
 
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12

Using Sulfuramidimidoyl Fluorides that Undergo Sulfur(VI) F..:

Brighty, Gabriel J ; Botham, Rachel C ; Li, Suhua...
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7541551/.  , 2020
Link: http://www.ncbi.nlm.nih...
 
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13

Small-Molecule Procaspase-3 Activation Sensitizes Cancer to..:

Botham, Rachel C ; Roth, Howard S ; Book, Alison P...
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999974/.  , 2016
Link: http://www.ncbi.nlm.nih...
 
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14

Removal of Metabolic Liabilities Enables Development of Der..:

Roth, Howard S ; Botham, Rachel C ; Schmid, Steven C...
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4520234/.  , 2015
Link: http://www.ncbi.nlm.nih...
 
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15

A Small Molecule that Induces Intrinsic Pathway Apoptosis w..:

Palchaudhuri, R. (Rahul) ; Lambrecht, M.J. (Michael J.) ; Botham, R.C. (Rachel C.)...
http://repub.eur.nl/pub/86709.  , 2015
Link: http://repub.eur.nl/pub/..
 
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