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Brodney, Michael
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1

Design and Synthesis of Clinical Candidate PF-06852231 (CVL..:

Butler, Christopher R. ; Popiolek, Michael ; McAllister, Laura A....
Journal of Medicinal Chemistry.  , 2024
Link: https://doi.org/10.1021/..
 
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2

Intramolecular Ring-Opening Decomposition of Aryl Azetidine:

Bai, Guoyun ; O'Connell, Thomas N. ; Brodney, Michael A....
ACS Medicinal Chemistry Letters.  12 (2021)  10 - p. 1585-1588 , 2021
Link: https://doi.org/10.1021/..
 
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3

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamic..:

Qiu, Ruolun ; Ahn, Jae Eun ; Alexander, Robert...
Journal of Alzheimer's Disease.  71 (2019)  2 - p. 581-595 , 2019
Link: https://doi.org/10.3233/..
 
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4

Palladium Catalyzed Hydrodefluorination of Fluoro-(hetero)a..:

Gair, Joseph J. ; Grey, Ronald L. ; Giroux, Simon.
Organic Letters.  21 (2019)  7 - p. 2482-2487 , 2019
Link: https://doi.org/10.1021/..
 
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5

Identification of a Novel Positron Emission Tomography (PET..:

Zhang, Lei ; Chen, Laigao ; Dutra, Jason K....
Journal of Medicinal Chemistry.  61 (2018)  8 - p. 3296-3308 , 2018
Link: https://doi.org/10.1021/..
 
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6

Utilizing structures of 2D6 and BACE1 to reduce risk of dru..:

Brodney, Michael
Drug Metabolism and Pharmacokinetics.  33 (2018)  1 - p. S14 , 2018
Link: https://doi.org/10.1016/..
 
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7

Late-Stage Microsomal Oxidation Reduces Drug–Drug Interacti..:

Stepan, Antonia F. ; Tran, Tuan P. ; Helal, Christopher J....
ACS Medicinal Chemistry Letters.  9 (2018)  2 - p. 68-72 , 2018
Link: https://doi.org/10.1021/..
 
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8

Discovery of Trifluoromethyl Glycol Carbamates as Potent an..:

McAllister, Laura A. ; Butler, Christopher R. ; Mente, Scot...
Journal of Medicinal Chemistry.  61 (2018)  7 - p. 3008-3026 , 2018
Link: https://doi.org/10.1021/..
 
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9

Harnessing biosynthesis and quantitative NMR for late stage..:

Brodney, Michael A. ; Sharma, Raman ; Lazzaro, John T...
Bioorganic & Medicinal Chemistry Letters.  28 (2018)  11 - p. 2068-2073 , 2018
Link: https://doi.org/10.1016/..
 
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10

Azetidine and Piperidine Carbamates as Efficient, Covalent ..:

Butler, Christopher R. ; Beck, Elizabeth M. ; Harris, Anthony...
Journal of Medicinal Chemistry.  60 (2017)  23 - p. 9860-9873 , 2017
Link: https://doi.org/10.1021/..
 
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11

Design and Synthesis of γ- and δ-Lactam M1 Positive Alloste..:

Davoren, Jennifer E. ; Garnsey, Michelle ; Pettersen, Betty...
Journal of Medicinal Chemistry.  60 (2017)  15 - p. 6649-6663 , 2017
Link: https://doi.org/10.1021/..
 
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12

Discovery of the Potent and Selective M1 PAM-Agonist N-[(3R..:

Davoren, Jennifer E. ; Lee, Che-Wah ; Garnsey, Michelle...
Journal of Medicinal Chemistry.  59 (2016)  13 - p. 6313-6328 , 2016
Link: https://doi.org/10.1021/..
 
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13

Aminomethyl-Derived Beta Secretase (BACE1) Inhibitors: Enga..:

Butler, Christopher R. ; Ogilvie, Kevin ; Martinez-Alsina, Luis...
Journal of Medicinal Chemistry.  60 (2016)  1 - p. 386-402 , 2016
Link: https://doi.org/10.1021/..
 
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14

Two Routes to 4-Fluorobenzisoxazol-3-one in the Synthesis o..:

Widlicka, Daniel W. ; Murray, John C. ; Coffman, Karen J....
Organic Process Research & Development.  20 (2016)  2 - p. 233-241 , 2016
Link: https://doi.org/10.1021/..
 
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15

P1‐106: Inhibition of Bace2 Affects Melanosome Ultrastructu..:

Nolan, Charles E. ; Karanian, David ; Chang, Cheng...
Alzheimer's & Dementia.  12 (2016)  7S_Part_9 - p. , 2016
Link: https://doi.org/10.1016/..
 
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