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Brough, Paul A.
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1

Ligand-Based Competition Binding by Real-Time 19F NMR in Hu..:

Luchinat, Enrico ; Barbieri, Letizia ; Davis, Ben...
Journal of Medicinal Chemistry.  67 (2024)  2 - p. 1115-1126 , 2024
Link: https://doi.org/10.1021/..
 
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2

Application of Off-Rate Screening in the Identification of ..:

Brough, Paul A. ; Baker, Lisa ; Bedford, Simon...
Journal of Medicinal Chemistry.  60 (2017)  6 - p. 2271-2286 , 2017
Link: https://doi.org/10.1021/..
 
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3

Off-Rate Screening (ORS) By Surface Plasmon Resonance. An E..:

Murray, James B. ; Roughley, Stephen D. ; Matassova, Natalia.
Journal of Medicinal Chemistry.  57 (2014)  7 - p. 2845-2850 , 2014
Link: https://doi.org/10.1021/..
 
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4

VER-246608, a novel pan-isoform ATP competitive inhibitor o..:

Moore, Jonathan D. ; Staniszewska, Anna ; Shaw, Terence...
Oncotarget.  5 (2014)  24 - p. 12862-12876 , 2014
Link: https://doi.org/10.18632..
 
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5

Targeting conserved water molecules: Design of 4-aryl-5-cya..:

Davies, Nicholas G.M. ; Browne, Helen ; Davis, Ben...
Bioorganic & Medicinal Chemistry.  20 (2012)  22 - p. 6770-6789 , 2012
Link: https://doi.org/10.1016/..
 
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6

Hsp90 Inhibitors and Drugs from Fragment and Virtual Screen..:

, In: Topics in Current Chemistry; Fragment-Based Drug Discovery and X-Ray Crystallography,
Roughley, Stephen ; Wright, Lisa ; Brough, Paul.. - p. 61-82 , 2011
Link: https://doi.org/10.1007/..
 
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7

Combining Hit Identification Strategies: Fragment-Based and..:

Brough, Paul A. ; Barril, Xavier ; Borgognoni, Jenifer...
Journal of Medicinal Chemistry.  52 (2009)  15 - p. 4794-4809 , 2009
Link: https://doi.org/10.1021/..
 
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8

4,5-Diarylisoxazole Hsp90 Chaperone Inhibitors: Potential T..:

Brough, Paul A. ; Aherne, Wynne ; Barril, Xavier...
Journal of Medicinal Chemistry.  51 (2007)  2 - p. 196-218 , 2007
Link: https://doi.org/10.1021/..
 
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9

Novel, Potent Small-Molecule Inhibitors of the Molecular Ch..:

Dymock, Brian W. ; Barril, Xavier ; Brough, Paul A....
Journal of Medicinal Chemistry.  48 (2005)  13 - p. 4212-4215 , 2005
Link: https://doi.org/10.1021/..
 
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10

3-(5-chloro-2,4-dihydroxyphenyl)-Pyrazole-4-carboxamides as..:

Brough, Paul A. ; Barril, Xavier ; Beswick, Mandy...
Bioorganic & Medicinal Chemistry Letters.  15 (2005)  23 - p. 5197-5201 , 2005
Link: https://doi.org/10.1016/..
 
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11

Structure-based discovery of a new class of Hsp90 inhibitor:

Barril, Xavier ; Brough, Paul ; Drysdale, Martin...
Bioorganic & Medicinal Chemistry Letters.  15 (2005)  23 - p. 5187-5191 , 2005
Link: https://doi.org/10.1016/..
 
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12

Synthesis of 2-iodo- and 2-phenyl-[11C]melatonin: potential..:

Chen, Jia Jun ; Fiehn-Schulze, Brita ; Brough, Paul A..
Applied Radiation and Isotopes.  49 (1998)  12 - p. 1573-1579 , 1998
Link: https://doi.org/10.1016/..
 
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13

Complex induced proximity effect enhancement in α-silyl car..:

Brough, Paul A. ; Fisher, Stephen ; Zhao, Baoping..
Tetrahedron Letters.  37 (1996)  17 - p. 2915-2918 , 1996
Link: https://doi.org/10.1016/..
 
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14

Anatoxin-a is a potent agonist of the nicotinic acetylcholi..:

Molloy, Leah ; Wonnacott, Susan ; Gallagher, Timothy..
European Journal of Pharmacology: Molecular Pharmacology.  289 (1995)  3 - p. 447-453 , 1995
Link: https://doi.org/10.1016/..
 
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15

Determination of Anatoxin-a, Homoanatoxin and Propylanatoxi..:

, In: Detection Methods for Cynobacterial Toxins,
Jefferies, Terry M. ; Brammer, Gavin ; Zotou, Anastasia.. - p. 34-39 , 1994
Link: https://doi.org/10.1533/..
 
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