E-LIB Suche - Ergebnisse für: Clarke, Michael O.

1

Discovery of GS-7682, a Novel 4′-Cyano-Modified C-Nucleosid..:

Siegel, Dustin S. ; Hui, Hon C. ; Pitts, Jared...
Journal of Medicinal Chemistry. 67 (2024) 15 - p. 12945-12968 , 2024

Link: https://doi.org/10.1021/..

2

Comparative therapeutic efficacy of remdesivir and combinat..:

Sheahan, Timothy P. ; Sims, Amy C. ; Leist, Sarah R....
Nature Communications. 11 (2020) 1 - p. , 2020

Link: https://doi.org/10.1038/..

3

Coronavirus Susceptibility to the Antiviral Remdesivir (GS-..:

Agostini, Maria L. ; Andres, Erica L. ; Sims, Amy C....
mBio. 9 (2018) 2 - p. , 2018

Link: https://doi.org/10.1128/..

4

Discovery and Synthesis of a Phosphoramidate Prodrug of a P..:

Siegel, Dustin ; Hui, Hon C. ; Doerffler, Edward...
Journal of Medicinal Chemistry. 60 (2017) 5 - p. 1648-1661 , 2017

Link: https://doi.org/10.1021/..

5

Discovery of a 2′-fluoro-2′- C -methyl C -nucleotide HCV po..:

Kirschberg, Thorsten A. ; Metobo, Sammy ; Clarke, Michael O....
Bioorganic & Medicinal Chemistry Letters. 27 (2017) 8 - p. 1840-1847 , 2017

Link: https://doi.org/10.1016/..

6

GS-5734 and its parent nucleoside analog inhibit Filo-, Pne..:

Lo, Michael K. ; Jordan, Robert ; Arvey, Aaron...
Scientific Reports. 7 (2017) 1 - p. , 2017

Link: https://doi.org/10.1038/..

7

Discovery of β-d-2′-deoxy-2′-α-fluoro-4′-α-cyano-5-aza-7,9-..:

Clarke, Michael O. ; Mackman, Richard ; Byun, Daniel...
Bioorganic & Medicinal Chemistry Letters. 25 (2015) 12 - p. 2484-2487 , 2015

Link: https://doi.org/10.1016/..

8

Discovery of GS-9669, a Thumb Site II Non-Nucleoside Inhibi..:

Lazerwith, Scott E. ; Lew, Willard ; Zhang, Jennifer...
Journal of Medicinal Chemistry. 57 (2013) 5 - p. 1893-1901 , 2013

Link: https://doi.org/10.1021/..

9

Discovery of GS-9451: An acid inhibitor of the hepatitis C ..:

Christopher Sheng, X. ; Appleby, Todd ; Butler, Thomas...
Bioorganic & Medicinal Chemistry Letters. 22 (2012) 7 - p. 2629-2634 , 2012

Link: https://doi.org/10.1016/..

10

Novel, potent and orally bioavailable indolizidinone-derive..:

Clarke, Michael O. ; Byun, Daniel ; Chen, Xiaowu...
Bioorganic & Medicinal Chemistry Letters. 22 (2012) 2 - p. 1095-1098 , 2012

Link: https://doi.org/10.1016/..

11

Discovery of GS-9256: A novel phosphinic acid derived inhib..:

Sheng, X. Christopher ; Casarez, Anthony ; Cai, Ruby...
Bioorganic & Medicinal Chemistry Letters. 22 (2012) 3 - p. 1394-1396 , 2012

Link: https://doi.org/10.1016/..

12

Synthesis of 1-amino-2-vinylcyclopropane-1-phosphinates. Co..:

Pyun, Hyung-Jung ; Clarke, Michael O. ; Cho, Aesop...
Tetrahedron Letters. 53 (2012) 18 - p. 2360-2363 , 2012

Link: https://doi.org/10.1016/..

13

Novel, potent, and orally bioavailable phosphinic acid inhi..:

Clarke, Michael O. ; Chen, Xiaowu ; Cho, Aesop...
Bioorganic & Medicinal Chemistry Letters. 21 (2011) 12 - p. 3568-3572 , 2011

Link: https://doi.org/10.1016/..

14

Optimization of Pharmacokinetics through Manipulation of Ph..:

Lazerwith, Scott E. ; Bahador, Gina ; Canales, Eda...
ACS Medicinal Chemistry Letters. 2 (2011) 10 - p. 715-719 , 2011

Link: https://doi.org/10.1021/..

15

Role of the A-Ring of Bryostatin Analogues in PKC Binding: ..:

Wender, Paul A. ; Clarke, Michael O. ; Horan, Joshua C.
Organic Letters. 7 (2005) 10 - p. 1995-1998 , 2005

Link: https://doi.org/10.1021/..