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Conrath, Katja
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1

Discovery of GLPG2737, a Potent Type 2 Corrector of CFTR fo..:

Pizzonero, Mathieu ; Akkari, Rhalid ; Bock, Xavier...
Journal of Medicinal Chemistry.  67 (2024)  7 - p. 5216-5232 , 2024
Link: https://doi.org/10.1021/..
 
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2

Correction to "Discovery of GLPG2451, a Novel Once Daily Po..:

Van der Plas, Steven E. ; Kelgtermans, Hans ; Mammoliti, Oscar...
Journal of Medicinal Chemistry.  64 (2021)  18 - p. 13933-13933 , 2021
Link: https://doi.org/10.1021/..
 
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3

Discovery of GLPG2451, a Novel Once Daily Potentiator for t..:

Van der Plas, Steven E. ; Kelgtermans, Hans ; Mammoliti, Oscar...
Journal of Medicinal Chemistry.  64 (2021)  1 - p. 343-353 , 2021
Link: https://doi.org/10.1021/..
 
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4

CFTR Rescue in Intestinal Organoids with GLPG/ABBV-2737, AB..:

de Poel, Eyleen ; Spelier, Sacha ; Korporaal, Ricardo...
Frontiers in Molecular Biosciences.  8 (2021)  - p. , 2021
Link: https://doi.org/10.3389/..
 
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5

Discovery of 9-Cyclopropylethynyl-2-((S)-1-[1,4]dioxan-2-yl..:

Labéguère, Frédéric ; Dupont, Sonia ; Alvey, Luke...
Journal of Medicinal Chemistry.  63 (2020)  22 - p. 13526-13545 , 2020
Link: https://doi.org/10.1021/..
 
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6

GLPG2737 in lumacaftor/ivacaftor-treated CF subjects homozy..:

van Koningsbruggen-Rietschel, Silke ; Conrath, Katja ; Fischer, Rainald...
Journal of Cystic Fibrosis.  19 (2020)  2 - p. 292-298 , 2020
Link: https://doi.org/10.1016/..
 
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7

Identifying the molecular target sites for CFTR potentiator..:

Yeh, Han-I ; Qiu, Liming ; Sohma, Yoshiro...
Journal of General Physiology.  151 (2019)  7 - p. 912-928 , 2019
Link: https://doi.org/10.1085/..
 
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8

GLPG1837, a CFTR potentiator, in p.Gly551Asp (G551D)-CF pat..:

Davies, Jane C. ; Van de Steen, Olivier ; van Koningsbruggen-Rietschel, Silke...
Journal of Cystic Fibrosis.  18 (2019)  5 - p. 693-699 , 2019
Link: https://doi.org/10.1016/..
 
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9

CFTR activity is enhanced by the novel corrector GLPG2222, ..:

Bell, Scott C. ; Barry, Peter J. ; De Boeck, Kris...
Journal of Cystic Fibrosis.  18 (2019)  5 - p. 700-707 , 2019
Link: https://doi.org/10.1016/..
 
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10

Identification of GLPG/ABBV-2737, a Novel Class of Correcto..:

de Wilde, Gert ; Gees, Maarten ; Musch, Sara...
Frontiers in Pharmacology.  10 (2019)  - p. , 2019
Link: https://doi.org/10.3389/..
 
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11

Correction to Discovery, Structure–Activity Relationship, a..:

Joncour, Agnès ; Desroy, Nicolas ; Housseman, Christopher...
Journal of Medicinal Chemistry.  61 (2018)  9 - p. 4270-4270 , 2018
Link: https://doi.org/10.1021/..
 
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12

Identification and Characterization of Novel CFTR Potentiat..:

Gees, Maarten ; Musch, Sara ; Van der Plas, Steven...
Frontiers in Pharmacology.  9 (2018)  - p. , 2018
Link: https://doi.org/10.3389/..
 
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13

Discovery of N-(3-Carbamoyl-5,5,7,7-tetramethyl-5,7-dihydro..:

Van der Plas, Steven E. ; Kelgtermans, Hans ; De Munck, Tom...
Journal of Medicinal Chemistry.  61 (2018)  4 - p. 1425-1435 , 2018
Link: https://doi.org/10.1021/..
 
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14

Discovery, Structure–Activity Relationship, and Binding Mod..:

Joncour, Agnès ; Desroy, Nicolas ; Housseman, Christopher...
Journal of Medicinal Chemistry.  60 (2017)  17 - p. 7371-7392 , 2017
Link: https://doi.org/10.1021/..
 
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15

A common mechanism for CFTR potentiators:

Yeh, Han-I ; Sohma, Yoshiro ; Conrath, Katja.
Journal of General Physiology.  149 (2017)  12 - p. 1105-1118 , 2017
Link: https://doi.org/10.1085/..
 
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