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Coulombe, René
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1

Discovery of Five SOS2 Fragment Hits with Binding Modes Det..:

Smith, Christopher R. ; Chen, Dan ; Christensen, James G....
Journal of Medicinal Chemistry.  67 (2023)  1 - p. 774-781 , 2023
Link: https://doi.org/10.1021/..
 
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2

Aligning Potency and Pharmacokinetic Properties for Pyridin..:

Fader, Lee D. ; Bailey, Murray ; Beaulieu, Eric...
ACS Medicinal Chemistry Letters.  7 (2016)  8 - p. 797-801 , 2016
Link: https://doi.org/10.1021/..
 
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3

Integrated Strategies for Identifying Leads That Target the..:

LaPlante, Steven R. ; Padyana, Anil K. ; Abeywardane, Asitha...
Journal of Medicinal Chemistry.  57 (2014)  5 - p. 2074-2090 , 2014
Link: https://doi.org/10.1021/..
 
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4

Minimizing the Contribution of Enterohepatic Recirculation ..:

Fader, Lee D. ; Carson, Rebekah ; Morin, Sébastien...
ACS Medicinal Chemistry Letters.  5 (2014)  6 - p. 711-716 , 2014
Link: https://doi.org/10.1021/..
 
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5

Discovery of BI 224436, a Noncatalytic Site Integrase Inhib..:

Fader, Lee D. ; Malenfant, Eric ; Parisien, Mathieu...
ACS Medicinal Chemistry Letters.  5 (2014)  4 - p. 422-427 , 2014
Link: https://doi.org/10.1021/..
 
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6

Discovery of a novel series of non-nucleoside thumb pocket ..:

Stammers, Timothy A. ; Coulombe, René ; Rancourt, Jean...
Bioorganic & Medicinal Chemistry Letters.  23 (2013)  9 - p. 2585-2589 , 2013
Link: https://doi.org/10.1016/..
 
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7

Molecular Dynamics Simulations and Structure-Based Rational..:

Hucke, Oliver ; Coulombe, René ; Bonneau, Pierre...
Journal of Medicinal Chemistry.  57 (2013)  5 - p. 1932-1943 , 2013
Link: https://doi.org/10.1021/..
 
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8

Monitoring Drug Self-Aggregation and Potential for Promiscu..:

LaPlante, Steven R. ; Aubry, Norman ; Bolger, Gordon...
Journal of Medicinal Chemistry.  56 (2013)  17 - p. 7073-7083 , 2013
Link: https://doi.org/10.1021/..
 
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9

N- versus O-alkylation: Utilizing NMR methods to establish ..:

LaPlante, Steven R. ; Bilodeau, François ; Aubry, Norman...
Bioorganic & Medicinal Chemistry Letters.  23 (2013)  16 - p. 4663-4668 , 2013
Link: https://doi.org/10.1016/..
 
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10

Inside Cover: Monitoring Binding of HIV‐1 Capsid Assembly I..:

Goudreau, Nathalie ; Coulombe, René ; Faucher, Anne‐Marie...
ChemMedChem.  8 (2013)  3 - p. 346-346 , 2013
Link: https://doi.org/10.1002/..
 
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11

Anthranilic acid-based Thumb Pocket 2 HCV NS5B polymerase i..:

Stammers, Timothy A. ; Coulombe, René ; Duplessis, Martin...
Bioorganic & Medicinal Chemistry Letters.  23 (2013)  24 - p. 6879-6885 , 2013
Link: https://doi.org/10.1016/..
 
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12

Structure-based design of novel HCV NS5B thumb pocket 2 all..:

Beaulieu, Pierre L. ; Coulombe, René ; Duan, Jianmin...
Bioorganic & Medicinal Chemistry Letters.  23 (2013)  14 - p. 4132-4140 , 2013
Link: https://doi.org/10.1016/..
 
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13

Monitoring Binding of HIV‐1 Capsid Assembly Inhibitors Usin..:

Goudreau, Nathalie ; Coulombe, René ; Faucher, Anne‐Marie...
ChemMedChem.  8 (2013)  3 - p. 405-414 , 2013
Link: https://doi.org/10.1002/..
 
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14

Enantiomeric Atropisomers Inhibit HCV Polymerase and/or HIV..:

LaPlante, Steven R. ; Forgione, Pat ; Boucher, Colette...
Journal of Medicinal Chemistry.  57 (2013)  5 - p. 1944-1951 , 2013
Link: https://doi.org/10.1021/..
 
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15

Compound Aggregation in Drug Discovery: Implementing a Prac..:

LaPlante, Steven R. ; Carson, Rebekah ; Gillard, James...
Journal of Medicinal Chemistry.  56 (2013)  12 - p. 5142-5150 , 2013
Link: https://doi.org/10.1021/..
 
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