E-LIB Suche - Ergebnisse für: Cummings, Richard T.

1

Comprehensive Target Engagement by the EZH2 Inhibitor Tulmi..:

Keller, Patricia J. ; Adams, Elizabeth J. ; Wu, Rentian...
Cancer Research. 84 (2024) 15 - p. 2501-2517 , 2024

2

Identification and characterization of second-generation EZ..:

Stuckey, Jacob I. ; Cantone, Nico R. ; Côté, Alexandre...
Journal of Biological Chemistry. 296 (2021) - p. 100349 , 2021

Link: https://doi.org/10.1016/..

3

Design, Synthesis, and Pharmacological Evaluation of Second..:

Khanna, Avinash ; Côté, Alexandre ; Arora, Shilpi...
ACS Medicinal Chemistry Letters. 11 (2020) 6 - p. 1205-1212 , 2020

Link: https://doi.org/10.1021/..

4

Design and Synthesis of Styrenylcyclopropylamine LSD1 Inhib..:

Gehling, Victor S. ; McGrath, John P. ; Duplessis, Martin...
ACS Medicinal Chemistry Letters. 11 (2020) 6 - p. 1213-1220 , 2020

Link: https://doi.org/10.1021/..

5

Discovery of CPI-1612: A Potent, Selective, and Orally Bioa..:

Wilson, Jonathan E. ; Patel, Gaurav ; Patel, Chirag...
ACS Medicinal Chemistry Letters. 11 (2020) 6 - p. 1324-1329 , 2020

Link: https://doi.org/10.1021/..

6

GNE-886: A Potent and Selective Inhibitor of the Cat Eye Sy..:

Crawford, Terry D. ; Audia, James E. ; Bellon, Steve...
ACS Medicinal Chemistry Letters. 8 (2017) 7 - p. 737-741 , 2017

Link: https://doi.org/10.1021/..

7

Regulatory T Cell Modulation by CBP/EP300 Bromodomain Inhib..:

Ghosh, Srimoyee ; Taylor, Alexander ; Chin, Melissa...
Journal of Biological Chemistry. 291 (2016) 25 - p. 13014-13027 , 2016

Link: https://doi.org/10.1074/..

8

Fragment-Based Discovery of a Selective and Cell-Active Ben..:

Taylor, Alexander M. ; Côté, Alexandre ; Hewitt, Michael C....
ACS Medicinal Chemistry Letters. 7 (2016) 5 - p. 531-536 , 2016

Link: https://doi.org/10.1021/..

9

Design and evaluation of 1,7-naphthyridones as novel KDM5 i..:

Labadie, Sharada S. ; Dragovich, Peter S. ; Cummings, Richard T....
Bioorganic & Medicinal Chemistry Letters. 26 (2016) 18 - p. 4492-4496 , 2016

Link: https://doi.org/10.1016/..

10

Identification of a Benzoisoxazoloazepine Inhibitor (CPI-06..:

Albrecht, Brian K. ; Gehling, Victor S. ; Hewitt, Michael C....
Journal of Medicinal Chemistry. 59 (2016) 4 - p. 1330-1339 , 2016

Link: https://doi.org/10.1021/..

11

Identification of potent, selective KDM5 inhibitors:

Gehling, Victor S. ; Bellon, Steven F. ; Harmange, Jean-Christophe...
Bioorganic & Medicinal Chemistry Letters. 26 (2016) 17 - p. 4350-4354 , 2016

Link: https://doi.org/10.1016/..

12

Identification of (R)-N-((4-Methoxy-6-methyl-2-oxo-1,2-dihy..:

Vaswani, Rishi G. ; Gehling, Victor S. ; Dakin, Les A....
Journal of Medicinal Chemistry. 59 (2016) 21 - p. 9928-9941 , 2016

Link: https://doi.org/10.1021/..

13

Discovery, design, and synthesis of indole-based EZH2 inhib..:

Gehling, Victor S. ; Vaswani, Rishi G. ; Nasveschuk, Christopher G....
Bioorganic & Medicinal Chemistry Letters. 25 (2015) 17 - p. 3644-3649 , 2015

Link: https://doi.org/10.1016/..

14

Discovery of Benzotriazolo[4,3-d][1,4]diazepines as Orally ..:

Taylor, Alexander M. ; Vaswani, Rishi G. ; Gehling, Victor S....
ACS Medicinal Chemistry Letters. 7 (2015) 2 - p. 145-150 , 2015

Link: https://doi.org/10.1021/..

15

EZH2 Inhibitor Efficacy in Non-Hodgkin's Lymphoma Does Not ..:

Bradley, William D. ; Arora, Shilpi ; Busby, Jennifer...
Chemistry & Biology. 21 (2014) 11 - p. 1463-1475 , 2014

Link: https://doi.org/10.1016/..