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Downey, Sondra L.
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1

Exploiting mitochondrial and metabolic homeostasis as a vul..:

Allaway, Robert J. ; Wood, Matthew D. ; Downey, Sondra L....
Oncotarget.  9 (2017)  22 - p. 15860-15875 , 2017
Link: https://doi.org/10.18632..
 
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2

Use of Proteasome Inhibitors:

Downey, Sondra L. ; Florea, Bogdan I. ; Overkleeft, Herman S..
Current Protocols in Immunology.  109 (2015)  1 - p. , 2015
Link: https://doi.org/10.1002/..
 
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3

Cell-line-specific high background in the Proteasome-Glo as..:

Wilkins, Owen M. ; Downey, Sondra L. ; Weyburne, Emily S....
Analytical Biochemistry.  451 (2014)  - p. 1-3 , 2014
Link: https://doi.org/10.1016/..
 
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4

Molecular Basis of Differential Sensitivity of Myeloma Cell..:

Shabaneh, Tamer B. ; Downey, Sondra L. ; Goddard, Ayrton L....
PLoS ONE.  8 (2013)  2 - p. e56132 , 2013
Link: https://doi.org/10.1371/..
 
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5

Phosphorylation of ΔNp63α via a Novel TGFβ/ALK5 Signaling M..:

Cherukuri, Pratima ; DeCastro, Andrew J. ; Balboni, Amanda L....
PLoS ONE.  7 (2012)  11 - p. e50066 , 2012
Link: https://doi.org/10.1371/..
 
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6

Specific Cell-Permeable Inhibitor of Proteasome Trypsin-lik..:

Mirabella, Anne C. ; Pletnev, Alexandre A. ; Downey, Sondra L....
Chemistry & Biology.  18 (2011)  5 - p. 608-618 , 2011
Link: https://doi.org/10.1016/..
 
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7

Nature of Pharmacophore Influences Active Site Specificity ..:

Screen, Michael ; Britton, Matthew ; Downey, Sondra L....
Journal of Biological Chemistry.  285 (2010)  51 - p. 40125-40134 , 2010
Link: https://doi.org/10.1074/..
 
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8

Incorporation of Fluorinated Phenylalanine Generates Highly..:

Geurink, Paul P. ; Liu, Nora ; Spaans, Michiel P....
Journal of Medicinal Chemistry.  53 (2010)  5 - p. 2319-2323 , 2010
Link: https://doi.org/10.1021/..
 
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9

Selective Inhibitor of Proteasome's Caspase-like Sites Sens..:

Britton, Matthew ; Lucas, Marcella M. ; Downey, Sondra L....
Chemistry & Biology.  16 (2009)  12 - p. 1278-1289 , 2009
Link: https://doi.org/10.1016/..
 
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10

Genome-scale functional genomics identify genes preferentia..:

de Matos Simoes, Ricardo ; Shirasaki, Ryosuke ; Downey-Kopyscinski, Sondra L....
Nature Cancer.  4 (2023)  5 - p. 754-773 , 2023
Link: https://doi.org/10.1038/..
 
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11

A clinically relevant pulse treatment generates a bortezomi..:

Downey-Kopyscinski, Sondra L. ; Srinivasa, Sriraja ; Kisselev, Alexei F.
Scientific Reports.  12 (2022)  1 - p. , 2022
Link: https://doi.org/10.1038/..
 
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12

M3258 Is a Selective Inhibitor of the Immunoproteasome Subu..:

Sanderson, Michael P. ; Friese-Hamim, Manja ; Walter-Bausch, Gina...
Molecular Cancer Therapeutics.  20 (2021)  8 - p. 1378-1387 , 2021
Link: https://doi.org/10.1158/..
 
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13

Activity of immunoproteasome inhibitor ONX-0914 in acute ly..:

Jenkins, Tyler W. ; Downey-Kopyscinski, Sondra L. ; Fields, Jennifer L....
Scientific Reports.  11 (2021)  1 - p. , 2021
Link: https://doi.org/10.1038/..
 
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14

Functional Genomics Identify Distinct and Overlapping Genes..:

Shirasaki, Ryosuke ; Matthews, Geoffrey M. ; Gandolfi, Sara...
Cell Reports.  34 (2021)  1 - p. 108532 , 2021
Link: https://doi.org/10.1016/..
 
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15

Gain-of-function studies with CRISPR-based transcriptional ..:

Tang, Huihui ; Shirasaki, Ryosuke ; Gandolfi, Sara...
Clinical Lymphoma Myeloma and Leukemia.  19 (2019)  10 - p. e49 , 2019
Link: https://doi.org/10.1016/..
 
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