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Edgar, Kyle A.
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1

Home-based exercise improves quality of life in breast and ..:

Bates-Fraser, Lauren C. ; Riley, Sasha ; Stopforth, Cameron...
PLOS ONE.  18 (2023)  4 - p. e0284427 , 2023
Link: https://doi.org/10.1371/..
 
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2

Discovery of GDC-0077 (Inavolisib), a Highly Selective Inhi..:

Hanan, Emily J. ; Braun, Marie-Gabrielle ; Heald, Robert A....
Journal of Medicinal Chemistry.  65 (2022)  24 - p. 16589-16621 , 2022
Link: https://doi.org/10.1021/..
 
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3

RTK-Dependent Inducible Degradation of Mutant PI3Kα Drives ..:

Song, Kyung W. ; Edgar, Kyle A. ; Hanan, Emily J....
Cancer Discovery.  12 (2021)  1 - p. 204-219 , 2021
Link: https://doi.org/10.1158/..
 
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4

Preclinical development of the PI3K Alpha selective and PIK..:

Pang, Jodie ; Baumgardner, Matthew ; Braun, Marie-Gabrielle...
Drug Metabolism and Pharmacokinetics.  34 (2019)  1 - p. S37 , 2019
Link: https://doi.org/10.1016/..
 
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5

Quantitative phosphoproteomic analysis of the PI3K-regulate..:

Gnad, Florian ; Wallin, Jeffrey ; Edgar, Kyle...
PROTEOMICS.  16 (2016)  14 - p. 1992-1997 , 2016
Link: https://doi.org/10.1002/..
 
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6

The Rational Design of Selective Benzoxazepin Inhibitors of..:

Heffron, Timothy P. ; Heald, Robert A. ; Ndubaku, Chudi...
Journal of Medicinal Chemistry.  59 (2016)  3 - p. 985-1002 , 2016
Link: https://doi.org/10.1021/..
 
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7

Discovery of Clinical Development Candidate GDC-0084, a Bra..:

Heffron, Timothy P. ; Ndubaku, Chudi O. ; Salphati, Laurent...
ACS Medicinal Chemistry Letters.  7 (2016)  4 - p. 351-356 , 2016
Link: https://doi.org/10.1021/..
 
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8

Discovery of 2-{3-[2-(1-Isopropyl-3-methyl-1H-1,2–4-triazol..:

Ndubaku, Chudi O. ; Heffron, Timothy P. ; Staben, Steven T....
Journal of Medicinal Chemistry.  56 (2013)  11 - p. 4597-4610 , 2013
Link: https://doi.org/10.1021/..
 
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9

Discovery of thiazolobenzoxepin PI3-kinase inhibitors that ..:

Staben, Steven T. ; Ndubaku, Chudi ; Blaquiere, Nicole...
Bioorganic & Medicinal Chemistry Letters.  23 (2013)  9 - p. 2606-2613 , 2013
Link: https://doi.org/10.1016/..
 
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10

Active PI3K Pathway Causes an Invasive Phenotype Which Can ..:

Wallin, Jeffrey J. ; Guan, Jane ; Edgar, Kyle A....
PLoS ONE.  7 (2012)  5 - p. e36402 , 2012
Link: https://doi.org/10.1371/..
 
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11

The Design and Identification of Brain Penetrant Inhibitors..:

Heffron, Timothy P. ; Salphati, Laurent ; Alicke, Bruno...
Journal of Medicinal Chemistry.  55 (2012)  18 - p. 8007-8020 , 2012
Link: https://doi.org/10.1021/..
 
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12

Synthetic Lethality of Retinoblastoma Mutant Cells in the D..:

Edgar, Kyle A ; Belvin, Marcia ; Parks, Annette L...
Genetics.  170 (2005)  1 - p. 161-171 , 2005
Link: https://doi.org/10.1534/..
 
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13

Systematic generation of high-resolution deletion coverage ..:

Parks, Annette L ; Cook, Kevin R ; Belvin, Marcia...
Nature Genetics.  36 (2004)  3 - p. 288-292 , 2004
Link: https://doi.org/10.1038/..
 
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14

Neuroendocrine factors affecting the steady-state levels of..:

Noriega, Fernando G ; Edgar, Kyle A ; Goodman, Walter G..
Journal of Insect Physiology.  47 (2001)  4-5 - p. 515-522 , 2001
Link: https://doi.org/10.1016/..
 
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15

Physical activity and sedentary behavior in people with spi..:

Bates, Lauren C. ; Conners, Ryan ; Zieff, Gabriel...
Disability and Health Journal.  15 (2022)  1 - p. 101177 , 2022
Link: https://doi.org/10.1016/..
 
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