E-LIB Suche - Ergebnisse für: Farnaby, William

1

Confounding Factors in Targeted Degradation of Short-Lived ..:

Vetma, Vesna ; Perez, Laura Casares ; Eliaš, Ján...
ACS Chemical Biology. 19 (2024) 7 - p. 1484-1494 , 2024

2

Breaking free from the crystal lattice: Structural biology ..:

Haubrich, Kevin ; Spiteri, Valentina A. ; Farnaby, William..
Current Opinion in Structural Biology. 79 (2023) - p. 102534 , 2023

Link: https://doi.org/10.1016/..

3

A selective and orally bioavailable VHL-recruiting PROTAC a..:

Kofink, Christiane ; Trainor, Nicole ; Mair, Barbara...
Nature Communications. 13 (2022) 1 - p. , 2022

Link: https://doi.org/10.1038/..

4

Discovery of Soticlestat, a Potent and Selective Inhibitor ..:

Koike, Tatsuki ; Yoshikawa, Masato ; Ando, Haruhi Kamisaki...
Journal of Medicinal Chemistry. 64 (2021) 16 - p. 12228-12244 , 2021

Link: https://doi.org/10.1021/..

5

Transforming targeted cancer therapy with PROTACs: A forwar..:

Farnaby, William ; Koegl, Manfred ; McConnell, Darryl B..
Current Opinion in Pharmacology. 57 (2021) - p. 175-183 , 2021

Link: https://doi.org/10.1016/..

6

Soticlestat, a novel cholesterol 24-hydroxylase inhibitor s..:

Nishi, Toshiya ; Kondo, Shinichi ; Miyamoto, Maki...
Scientific Reports. 10 (2020) 1 - p. , 2020

Link: https://doi.org/10.1038/..

7

Protein degradation for drug discovery:

Ciulli, Alessio ; Farnaby, William
Drug Discovery Today: Technologies. 31 (2019) - p. 1-3 , 2019

Link: https://doi.org/10.1016/..

8

SPR-Measured Dissociation Kinetics of PROTAC Ternary Comple..:

Roy, Michael J. ; Winkler, Sandra ; Hughes, Scott J....
ACS Chemical Biology. 14 (2019) 3 - p. 361-368 , 2019

Link: https://doi.org/10.1021/..

9

Identification of compounds acting as negative allosteric m..:

Ellery, Jonathan ; Dickson, Louise ; Cheung, Toni...
European Journal of Pharmacology. 833 (2018) - p. 8-15 , 2018

Link: https://doi.org/10.1016/..

10

Modular synthesis of thirty lead-like scaffolds suitable fo..:

Mayol-Llinàs, Joan ; Farnaby, William ; Nelson, Adam
Chemical Communications. 53 (2017) 91 - p. 12345-12348 , 2017

Link: https://doi.org/10.1039/..

11

Assessing molecular scaffolds for CNS drug discovery:

Mayol-Llinàs, Joan ; Nelson, Adam ; Farnaby, William.
Drug Discovery Today. 22 (2017) 7 - p. 965-969 , 2017

Link: https://doi.org/10.1016/..

12

Synthesis of (−)-(S,S)-clemastine by Invertive N → C Aryl M..:

Fournier, Anne M. ; Brown, Robert A. ; Farnaby, William..
Organic Letters. 12 (2010) 10 - p. 2222-2225 , 2010

Link: https://doi.org/10.1021/..

13

N to C Aryl Migration in Lithiated Carbamates: α-Arylation ..:

Clayden, Jonathan ; Farnaby, William ; Grainger, Damian M....
Journal of the American Chemical Society. 131 (2009) 10 - p. 3410-3411 , 2009

Link: https://doi.org/10.1021/..

14

A selective and orally bioavailable VHL-recruiting PROTAC a..:

Kofink, Christiane ; Trainor, Nicole ; Mair, Barbara...
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9551036/. , 2022

Link: http://www.ncbi.nlm.nih...

15

Soticlestat, a novel cholesterol 24-hydroxylase inhibitor s..:

Nishi, Toshiya ; Kondo, Shinichi ; Miyamoto, Maki...
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7553946/. , 2020

Link: http://www.ncbi.nlm.nih...