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Fitzek, Martina
31  results:
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1

A phenotypic screen of Marfan syndrome iPSC-derived vascula..:

Davaapil, Hongorzul ; McNamara, Madeline ; Granata, Alessandra...
Stem Cell Reports.  18 (2023)  2 - p. 555-569 , 2023
Link: https://doi.org/10.1016/..
 
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2

A small-molecule PI3Kα activator for cardioprotection and n..:

Gong, Grace Q. ; Bilanges, Benoit ; Allsop, Ben...
Nature.  618 (2023)  7963 - p. 159-168 , 2023
Link: https://doi.org/10.1038/..
 
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3

Fragment-Based Screening Identifies New Quinazolinone-Based..:

Heitmann, Tyler ; Liao, Gangling ; de León, Pablo...
ACS Medicinal Chemistry Letters.  14 (2023)  12 - p. 1760-1766 , 2023
Link: https://doi.org/10.1021/..
 
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4

Phenotypic high-throughput screening platform identifies no..:

Brito, Hugo ; Marques, Vanda ; Afonso, Marta B....
Cell Death Discovery.  6 (2020)  1 - p. , 2020
Link: https://doi.org/10.1038/..
 
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5

A small molecule inhibitor of HER3: a proof-of-concept stud:

Colomba, Audrey ; Fitzek, Martina ; George, Roger...
Biochemical Journal.  477 (2020)  17 - p. 3329-3347 , 2020
Link: https://doi.org/10.1042/..
 
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6

Pluripotent Stem Cell-Derived Hepatocytes Phenotypic Screen..:

Parafati, Maddalena ; Bae, Sang Hyo ; Kirby, R. Jason...
International Journal of Molecular Sciences.  21 (2020)  24 - p. 9557 , 2020
Link: https://doi.org/10.3390/..
 
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7

Discovery of a novel aminopyrazine series as selective PI3K..:

Barlaam, Bernard ; Cosulich, Sabina ; Fitzek, Martina...
Bioorganic & Medicinal Chemistry Letters.  27 (2017)  13 - p. 3030-3035 , 2017
Link: https://doi.org/10.1016/..
 
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8

Discovery of a series of 8-(1-phenylpyrrolidin-2-yl)-6-carb..:

Barlaam, Bernard ; Cosulich, Sabina ; Degorce, Sébastien...
Bioorganic & Medicinal Chemistry Letters.  27 (2017)  9 - p. 1949-1954 , 2017
Link: https://doi.org/10.1016/..
 
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9

Discovery of a series of 8-(2,3-dihydro-1,4-benzoxazin-4-yl..:

Barlaam, Bernard ; Cosulich, Sabina ; Degorce, Sébastien...
Bioorganic & Medicinal Chemistry Letters.  26 (2016)  9 - p. 2318-2323 , 2016
Link: https://doi.org/10.1016/..
 
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10

Design of selective PI3Kα inhibitors starting from a promis..:

Barlaam, Bernard ; Cosulich, Sabina ; Fitzek, Martina...
Bioorganic & Medicinal Chemistry Letters.  25 (2015)  13 - p. 2679-2685 , 2015
Link: https://doi.org/10.1016/..
 
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11

Discovery of (R)-8-(1-(3,5-Difluorophenylamino)ethyl)-N,N-d..:

Barlaam, Bernard ; Cosulich, Sabina ; Degorce, Sébastien...
Journal of Medicinal Chemistry.  58 (2015)  2 - p. 943-962 , 2015
Link: https://doi.org/10.1021/..
 
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12

Discovery of 1-(4-(5-(5-amino-6-(5-tert-butyl-1,3,4-oxadiaz..:

Barlaam, Bernard ; Cosulich, Sabina ; Delouvrié, Bénédicte...
Bioorganic & Medicinal Chemistry Letters.  25 (2015)  22 - p. 5155-5162 , 2015
Link: https://doi.org/10.1016/..
 
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13

Discovery of 9-(1-anilinoethyl)-2-morpholino-4-oxo-pyrido[1..:

Barlaam, Bernard ; Cosulich, Sabina ; Degorce, Sébastien...
Bioorganic & Medicinal Chemistry Letters.  24 (2014)  16 - p. 3928-3935 , 2014
Link: https://doi.org/10.1016/..
 
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14

Discovery of novel imidazo[1,2-a]pyridines as inhibitors of..:

Ducray, Richard ; Simpson, Iain ; Jung, Frederic H....
Bioorganic & Medicinal Chemistry Letters.  21 (2011)  16 - p. 4698-4701 , 2011
Link: https://doi.org/10.1016/..
 
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15

Discovery of imidazole vinyl pyrimidines as a novel class o..:

Buttar, David ; Edge, Mike ; Emery, Steve C....
Bioorganic & Medicinal Chemistry Letters.  18 (2008)  16 - p. 4723-4726 , 2008
Link: https://doi.org/10.1016/..
 
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