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Focken, Thilo
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1

Molecular Pharmacology of Selective NaV1.6 and Dual NaV1.6/..:

Goodchild, Samuel J. ; Shuart, Noah Gregory ; Williams, Aaron D....
ACS Chemical Neuroscience.  15 (2024)  6 - p. 1169-1184 , 2024
Link: https://doi.org/10.1021/..
 
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2

The contribution of NaV1.6 to the efficacy of voltage‐gated..:

Johnson Jr, James P. ; Focken, Thilo ; Karimi Tari, Parisa...
British Journal of Pharmacology.  , 2024
Link: https://doi.org/10.1111/..
 
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3

NBI-921352, a first-in-class, NaV1.6 selective, sodium chan..:

Johnson, JP ; Focken, Thilo ; Khakh, Kuldip...
eLife.  11 (2022)  - p. , 2022
Link: https://doi.org/10.7554/..
 
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4

Discovery of Acyl-sulfonamide Nav1.7 Inhibitors GDC-0276 an..:

Safina, Brian S. ; McKerrall, Steven J. ; Sun, Shaoyi...
Journal of Medicinal Chemistry.  64 (2021)  6 - p. 2953-2966 , 2021
Link: https://doi.org/10.1021/..
 
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5

Identification of CNS-Penetrant Aryl Sulfonamides as Isofor..:

Focken, Thilo ; Burford, Kristen ; Grimwood, Michael E....
Journal of Medicinal Chemistry.  62 (2019)  21 - p. 9618-9641 , 2019
Link: https://doi.org/10.1021/..
 
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6

Identification of Selective Acyl Sulfonamide–Cycloalkylethe..:

Sun, Shaoyi ; Jia, Qi ; Zenova, Alla Y....
Journal of Medicinal Chemistry.  62 (2018)  2 - p. 908-927 , 2018
Link: https://doi.org/10.1021/..
 
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7

Design of Conformationally Constrained Acyl Sulfonamide Iso..:

Focken, Thilo ; Chowdhury, Sultan ; Zenova, Alla...
Journal of Medicinal Chemistry.  61 (2018)  11 - p. 4810-4831 , 2018
Link: https://doi.org/10.1021/..
 
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8

Discovery of Aryl Sulfonamides as Isoform-Selective Inhibit..:

Focken, Thilo ; Liu, Shifeng ; Chahal, Navjot...
ACS Medicinal Chemistry Letters.  7 (2016)  3 - p. 277-282 , 2016
Link: https://doi.org/10.1021/..
 
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9

Structural basis of Nav1.7 inhibition by an isoform-selecti..:

Ahuja, Shivani ; Mukund, Susmith ; Deng, Lunbin...
Science.  350 (2015)  6267 - p. , 2015
Link: https://doi.org/10.1126/..
 
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10

Structural basis of Nav1.7 inhibition by an isoform-selecti..:

Ahuja, Shivani ; Mukund, Susmith ; Deng, Lunbin...
Science.  350 (2015)  6267 - p. 1491 ff. , 2015
Link: http://www.jstor.org/sta..
 
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11

Application of cyclic phosphonamide reagents in the total s..:

Focken, Thilo ; Hanessian, Stephen
Beilstein Journal of Organic Chemistry.  10 (2014)  - p. 1848-1877 , 2014
Link: https://doi.org/10.3762/..
 
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12

Lewis-acid catalyzed formation of dihydropyrans:

Hanessian, Stephen ; Focken, Thilo ; Oza, Rupal
Tetrahedron.  67 (2011)  51 - p. 9870-9884 , 2011
Link: https://doi.org/10.1016/..
 
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13

Total Synthesis of Jerangolid A:

Hanessian, Stephen ; Focken, Thilo ; Oza, Rupal
Organic Letters.  12 (2010)  14 - p. 3172-3175 , 2010
Link: https://doi.org/10.1021/..
 
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14

Total Synthesis of (+)-Ambruticin S: Probing the Pharmacoph..:

Hanessian, Stephen ; Focken, Thilo ; Mi, Xueling...
The Journal of Organic Chemistry.  75 (2010)  16 - p. 5601-5618 , 2010
Link: https://doi.org/10.1021/..
 
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15

Stereoselective Synthesis of Pyridinones:  Application to t..:

Focken, Thilo ; Charette, André B.
Organic Letters.  8 (2006)  14 - p. 2985-2988 , 2006
Link: https://doi.org/10.1021/..
 
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