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Gadkar, Kapil
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1

A Minimal PBPK/PD Model with Expansion-Enhanced Target-Medi..:

Hosseini, Iraj ; Fleisher, Brett ; Getz, Jennifer...
Pharmaceutics.  16 (2024)  5 - p. 660 , 2024
Link: https://doi.org/10.3390/..
 
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2

Systems‐based digital twins to help characterize clinical d..:

Susilo, Monica E. ; Li, Chi‐Chung ; Gadkar, Kapil...
Clinical and Translational Science.  16 (2023)  7 - p. 1134-1148 , 2023
Link: https://doi.org/10.1111/..
 
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3

A TREM2-activating antibody with a blood–brain barrier tran..:

van Lengerich, Bettina ; Zhan, Lihong ; Xia, Dan...
Nature Neuroscience.  , 2023
Link: https://doi.org/10.1038/..
 
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4

Integrated systems modeling of severe asthma: Exploration o..:

Gadkar, Kapil ; Feigelman, Justin ; Sukumaran, Siddharth...
CPT: Pharmacometrics & Systems Pharmacology.  11 (2022)  9 - p. 1268-1277 , 2022
Link: https://doi.org/10.1002/..
 
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5

Quantitative systems pharmacology model‐based investigation..:

Gadkar, Kapil ; Friedrich, Christina ; Hurez, Vincent...
CPT: Pharmacometrics & Systems Pharmacology.  11 (2021)  5 - p. 616-627 , 2021
Link: https://doi.org/10.1002/..
 
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6

Mitigating the risk of cytokine release syndrome in a Phase..:

Hosseini, Iraj ; Gadkar, Kapil ; Stefanich, Eric...
npj Systems Biology and Applications.  6 (2020)  1 - p. , 2020
Link: https://doi.org/10.1038/..
 
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7

SC3.4 - Therapeutic area case study: QSP in inflammatory di..:

Gadkar, Kapil
Drug Metabolism and Pharmacokinetics.  35 (2020)  1 - p. S3-S4 , 2020
Link: https://doi.org/10.1016/..
 
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8

gQSPSim: A SimBiology‐Based GUI for Standardized QSP Model ..:

Hosseini, Iraj ; Feigelman, Justin ; Gajjala, Anita...
CPT: Pharmacometrics & Systems Pharmacology.  9 (2020)  3 - p. 165-176 , 2020
Link: https://doi.org/10.1002/..
 
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9

A Quantitative Systems Pharmacology Consortium Approach to ..:

Kierzek, Andrzej M. ; Hickling, Timothy P. ; Figueroa, Isabel...
CPT: Pharmacometrics & Systems Pharmacology.  8 (2019)  11 - p. 773-776 , 2019
Link: https://doi.org/10.1002/..
 
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10

gPKPDSim: a SimBiology®-based GUI application for PKPD mode..:

Hosseini, Iraj ; Gajjala, Anita ; Bumbaca Yadav, Daniela...
Journal of Pharmacokinetics and Pharmacodynamics.  45 (2018)  2 - p. 259-275 , 2018
Link: https://doi.org/10.1007/..
 
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11

Widespread brain distribution and activity following i.c.v...:

Yadav, Daniela Bumbaca ; Maloney, Janice A ; Wildsmith, Kristin R...
British Journal of Pharmacology.  174 (2017)  22 - p. 4173-4185 , 2017
Link: https://doi.org/10.1111/..
 
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12

Ocular Pharmacokinetics of Therapeutic Antibodies Given by ..:

Hutton-Smith, Laurence A. ; Gaffney, Eamonn A. ; Byrne, Helen M....
Molecular Pharmaceutics.  14 (2017)  8 - p. 2690-2696 , 2017
Link: https://doi.org/10.1021/..
 
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13

Erratum: Clinical responses to ERK inhibition in BRAF V600E..:

Kirouac, Daniel C. ; Schaefer, Gabriele ; Chan, Jocelyn...
npj Systems Biology and Applications.  3 (2017)  1 - p. , 2017
Link: https://doi.org/10.1038/..
 
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14

Clinical responses to ERK inhibition in BRAF V600E-mutant c..:

Kirouac, Daniel C. ; Schaefer, Gabriele ; Chan, Jocelyn...
npj Systems Biology and Applications.  3 (2017)  1 - p. , 2017
Link: https://doi.org/10.1038/..
 
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15

Mathematical PKPD and safety model of bispecific TfR/BACE1 ..:

Gadkar, Kapil ; Yadav, Daniela Bumbaca ; Zuchero, Joy Yu...
European Journal of Pharmaceutics and Biopharmaceutics.  101 (2016)  - p. 53-61 , 2016
Link: https://doi.org/10.1016/..
 
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