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Graves, Bradford
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1

FT-6876, a Potent and Selective Inhibitor of CBP/p300, is A..:

Caligiuri, Maureen ; Williams, Grace L. ; Castro, Jennifer...
Targeted Oncology.  18 (2023)  2 - p. 269-285 , 2023
Link: https://doi.org/10.1007/..
 
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2

Discovery of Sulanemadlin (ALRN-6924), the First Cell-Perme..:

Guerlavais, Vincent ; Sawyer, Tomi K. ; Carvajal, Luis...
Journal of Medicinal Chemistry.  66 (2023)  14 - p. 9401-9417 , 2023
Link: https://doi.org/10.1021/..
 
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3

Distinct USP25 and USP28 Oligomerization States Regulate De..:

Gersch, Malte ; Wagstaff, Jane L. ; Toms, Angela V....
Molecular Cell.  74 (2019)  3 - p. 436-451.e7 , 2019
Link: https://doi.org/10.1016/..
 
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4

Discovery of potent and selective spiroindolinone MDM2 inhi..:

Zhang, Zhuming ; Ding, Qingjie ; Liu, Jin-Jun...
Bioorganic & Medicinal Chemistry.  22 (2014)  15 - p. 4001-4009 , 2014
Link: https://doi.org/10.1016/..
 
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5

Discovery of Potent and Orally Active p53-MDM2 Inhibitors R..:

Zhang, Zhuming ; Chu, Xin-Jie ; Liu, Jin-Jun...
ACS Medicinal Chemistry Letters.  5 (2014)  2 - p. 124-127 , 2014
Link: https://doi.org/10.1021/..
 
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6

Discovery of RG7388, a Potent and Selective p53–MDM2 Inhibi..:

Ding, Qingjie ; Zhang, Zhuming ; Liu, Jin-Jun...
Journal of Medicinal Chemistry.  56 (2013)  14 - p. 5979-5983 , 2013
Link: https://doi.org/10.1021/..
 
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7

Discovery of RG7112: A Small-Molecule MDM2 Inhibitor in Cli..:

Vu, Binh ; Wovkulich, Peter ; Pizzolato, Giacomo...
ACS Medicinal Chemistry Letters.  4 (2013)  5 - p. 466-469 , 2013
Link: https://doi.org/10.1021/..
 
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8

Stapled α−helical peptide drug development: A potent dual i..:

Chang, Yong S. ; Graves, Bradford ; Guerlavais, Vincent...
Proceedings of the National Academy of Sciences.  110 (2013)  36 - p. , 2013
Link: https://doi.org/10.1073/..
 
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9

Deconstruction of a Nutlin: Dissecting the Binding Determin..:

Fry, David C. ; Wartchow, Charles ; Graves, Bradford...
ACS Medicinal Chemistry Letters.  4 (2013)  7 - p. 660-665 , 2013
Link: https://doi.org/10.1021/..
 
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10

Activation of the p53 pathway by small-moleculeinduced MDM2..:

Graves, Bradford ; Thompson, Thelma ; Xia, Mingxuan...
Proceedings of the National Academy of Sciences of the United States of America.  109 (2012)  29 - p. 11788-11793 , 2012
Link: https://www.jstor.org/st..
 
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11

Effect of the MDM2 antagonist RG7112 on the P53 pathway in ..:

Ray-Coquard, Isabelle ; Blay, Jean-Yves ; Italiano, Antoine...
The Lancet Oncology.  13 (2012)  11 - p. 1133-1140 , 2012
Link: https://doi.org/10.1016/..
 
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12

Activation of the p53 pathway by small-molecule-induced MDM..:

Graves, Bradford ; Thompson, Thelma ; Xia, Mingxuan...
Proceedings of the National Academy of Sciences.  109 (2012)  29 - p. 11788-11793 , 2012
Link: https://doi.org/10.1073/..
 
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13

Discovery of 6-(2,4-Difluorophenoxy)-2-[3-hydroxy-1-(2-hydr..:

Goldstein, David M. ; Soth, Michael ; Gabriel, Tobias...
Journal of Medicinal Chemistry.  54 (2011)  7 - p. 2255-2265 , 2011
Link: https://doi.org/10.1021/..
 
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14

Discovery of [4-Amino-2-(1-methanesulfonylpiperidin-4-ylami..:

Chu, Xin-Jie ; DePinto, Wanda ; Bartkovitz, David...
Journal of Medicinal Chemistry.  49 (2006)  22 - p. 6549-6560 , 2006
Link: https://doi.org/10.1021/..
 
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15

In vivo Activation of the p53 Pathway by Small-Molecule Ant..:

Vassilev, Lyubomir T. ; Vu, Binh T. ; Graves, Bradford...
Science.  303 (2004)  5659 - p. 844-848 , 2004
Link: https://www.jstor.org/st..
 
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