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Guernon, Jason
21  results:
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1

Discovery of new indole-based acylsulfonamide Nav1.7 inhibi..:

Wu, Yong-Jin ; Venables, Brian ; Guernon, Jason...
Bioorganic & Medicinal Chemistry Letters.  29 (2019)  4 - p. 659-663 , 2019
Link: https://doi.org/10.1016/..
 
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2

Discovery of morpholine-based aryl sulfonamides as Na v 1.7..:

Wu, Yong-Jin ; Guernon, Jason ; McClure, Andrea...
Bioorganic & Medicinal Chemistry Letters.  28 (2018)  5 - p. 958-962 , 2018
Link: https://doi.org/10.1016/..
 
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3

Development of New Benzenesulfonamides As Potent and Select..:

Wu, Yong-Jin ; Guernon, Jason ; Shi, Jianliang...
Journal of Medicinal Chemistry.  60 (2017)  6 - p. 2513-2525 , 2017
Link: https://doi.org/10.1021/..
 
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4

Discovery of non-zwitterionic aryl sulfonamides as Nav1.7 i..:

Wu, Yong-Jin ; Guernon, Jason ; McClure, Andrea...
Bioorganic & Medicinal Chemistry.  25 (2017)  20 - p. 5490-5505 , 2017
Link: https://doi.org/10.1016/..
 
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5

Discovery of S3-Truncated, C-6 Heteroaryl Substituted Amino..:

Wu, Yong-Jin ; Guernon, Jason ; Shi, Jianliang...
Journal of Medicinal Chemistry.  59 (2016)  18 - p. 8593-8600 , 2016
Link: https://doi.org/10.1021/..
 
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6

Targeting the BACE1 Active Site Flap Leads to a Potent Inhi..:

Wu, Yong-Jin ; Guernon, Jason ; Yang, Fukang...
ACS Medicinal Chemistry Letters.  7 (2016)  3 - p. 271-276 , 2016
Link: https://doi.org/10.1021/..
 
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7

Discovery of furo[2,3- d ][1,3]thiazinamines as beta amyloi..:

Wu, Yong-Jin ; Guernon, Jason ; Rajamani, Ramkumar...
Bioorganic & Medicinal Chemistry Letters.  26 (2016)  23 - p. 5729-5731 , 2016
Link: https://doi.org/10.1016/..
 
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8

Expedient Synthesis of Furo[2,3-d][1,3]thiazinamines and Py..:

Wu, Yong-Jin ; Guernon, Jason ; Park, Hyunsoo.
The Journal of Organic Chemistry.  81 (2016)  8 - p. 3386-3390 , 2016
Link: https://doi.org/10.1021/..
 
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9

Synthesis of β-disubstituted β-amino isoxazolyl ketones by ..:

Guernon, Jason ; Marcin, Lawrence ; Higgins, Mendi...
Tetrahedron Letters.  55 (2014)  13 - p. 2134-2137 , 2014
Link: https://doi.org/10.1016/..
 
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10

2,5-Bis-(sulfonyl)pyrazines as unprecedented building block..:

Li, Jie Jack ; Meng, Wei ; Wu, Shung...
Tetrahedron Letters.  54 (2013)  15 - p. 1938-1942 , 2013
Link: https://doi.org/10.1016/..
 
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11

The discovery of VU0652957 (VU2957, Valiglurax): SAR and DM..:

Panarese, Joseph D. ; Engers, Darren W. ; Wu, Yong-Jin...
Bioorganic & Medicinal Chemistry Letters.  29 (2019)  2 - p. 342-346 , 2019
Link: https://doi.org/10.1016/..
 
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12

Identification and Preclinical Evaluation of the Bicyclic P..:

Boy, Kenneth M. ; Guernon, Jason M. ; Zuev, Dmitry S....
ACS Medicinal Chemistry Letters.  10 (2019)  3 - p. 312-317 , 2019
Link: https://doi.org/10.1021/..
 
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13

Macrocyclic prolinyl acyl guanidines as inhibitors of β-sec..:

Boy, Kenneth M. ; Guernon, Jason M. ; Wu, Yong-Jin...
Bioorganic & Medicinal Chemistry Letters.  25 (2015)  22 - p. 5040-5047 , 2015
Link: https://doi.org/10.1016/..
 
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14

Monosubstituted γ-lactam and conformationally constrained 1..:

Boy, Kenneth M. ; Guernon, Jason M. ; Shi, Jianliang...
Bioorganic & Medicinal Chemistry Letters.  21 (2011)  22 - p. 6916-6924 , 2011
Link: https://doi.org/10.1016/..
 
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15

Synthesis and in vivo evaluation of cyclic diaminopropane B..:

Thompson, Lorin A. ; Shi, Jianliang ; Decicco, Carl P....
Bioorganic & Medicinal Chemistry Letters.  21 (2011)  22 - p. 6909-6915 , 2011
Link: https://doi.org/10.1016/..
 
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