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Hakkola, Jukka
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1

Inhibition of activin receptor 2 signalling ameliorates met..:

Swan, Julia ; Szabó, Zoltán ; Peters, Juliana...
Biomedicine & Pharmacotherapy.  175 (2024)  - p. 116683 , 2024
Link: https://doi.org/10.1016/..
 
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2

Metabolic effects of nuclear receptor activation in vivo af..:

Attema, Brecht ; Kummu, Outi ; Pitkänen, Sini...
Archives of Toxicology.  98 (2024)  3 - p. 911-928 , 2024
Link: https://doi.org/10.1007/..
 
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3

Adverse outcome pathway for pregnane X receptor-induced hyp..:

Itkonen, Anna ; Hakkola, Jukka ; Rysä, Jaana
Archives of Toxicology.  97 (2023)  11 - p. 2861-2877 , 2023
Link: https://doi.org/10.1007/..
 
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4

Pregnane X receptor activation remodels glucose metabolism ..:

Karpale, Mikko ; Kummu, Outi ; Kärkkäinen, Olli...
Molecular Metabolism.  76 (2023)  - p. 101779 , 2023
Link: https://doi.org/10.1016/..
 
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5

Nuclear Receptor PXR in Drug-Induced Hypercholesterolemia:

Karpale, Mikko ; Hukkanen, Janne ; Hakkola, Jukka
Cells.  11 (2022)  3 - p. 313 , 2022
Link: https://doi.org/10.3390/..
 
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6

Streptozotocin-induced Diabetes Represses Hepatic CYP2R1 Ex..:

Elkhwanky, Mahmoud-Sobhy ; Kummu, Outi ; Hakkola, Jukka
Endocrinology.  163 (2022)  7 - p. , 2022
Link: https://doi.org/10.1210/..
 
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7

Pregnane X Receptor‒4β‐Hydroxycholesterol Axis in the Regul..:

Rahunen, Roosa ; Kummu, Outi ; Koivukangas, Vesa...
Journal of the American Heart Association.  11 (2022)  6 - p. , 2022
Link: https://doi.org/10.1161/..
 
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8

Activation of pregnane X receptor induces atherogenic lipid..:

Karpale, Mikko ; Käräjämäki, Aki Juhani ; Kummu, Outi...
British Journal of Pharmacology.  178 (2021)  12 - p. 2461-2481 , 2021
Link: https://doi.org/10.1111/..
 
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9

Rifampicin induces the bone form of alkaline phosphatase in..:

Nabil, Heba ; Kummu, Outi ; Lehenkari, Petri...
Basic & Clinical Pharmacology & Toxicology.  130 (2021)  S1 - p. 81-94 , 2021
Link: https://doi.org/10.1111/..
 
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10

Inhibition and induction of CYP enzymes in humans: an updat:

Hakkola, Jukka ; Hukkanen, Janne ; Turpeinen, Miia.
Archives of Toxicology.  94 (2020)  11 - p. 3671-3722 , 2020
Link: https://doi.org/10.1007/..
 
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11

PXR and 4β-Hydroxycholesterol Axis and the Components of Me..:

Hukkanen, Janne ; Hakkola, Jukka
Cells.  9 (2020)  11 - p. 2445 , 2020
Link: https://doi.org/10.3390/..
 
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12

4β-Hydroxycholesterol Signals From the Liver to Regulate Pe..:

Salonurmi, Tuire ; Nabil, Heba ; Ronkainen, Justiina...
Frontiers in Pharmacology.  11 (2020)  - p. , 2020
Link: https://doi.org/10.3389/..
 
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13

The EDCMET Project: Metabolic Effects of Endocrine Disrupto..:

Küblbeck, Jenni ; Vuorio, Taina ; Niskanen, Jonna...
International Journal of Molecular Sciences.  21 (2020)  8 - p. 3021 , 2020
Link: https://doi.org/10.3390/..
 
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14

Obesity Represses CYP2R1, the Vitamin D 25‐Hydroxylase, in ..:

Elkhwanky, Mahmoud‐Sobhy ; Kummu, Outi ; Piltonen, Terhi T...
JBMR Plus.  4 (2020)  11 - p. , 2020
Link: https://doi.org/10.1002/..
 
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15

Pregnane X Receptor Activator Rifampin Increases Blood Pres..:

Hassani‐Nezhad‐Gashti, Fatemeh ; Salonurmi, Tuire ; Hautajärvi, Heidi...
Clinical Pharmacology & Therapeutics.  108 (2020)  4 - p. 856-865 , 2020
Link: https://doi.org/10.1002/..
 
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