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Hamblin, J Nicole
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1

Developing inhaled drugs for respiratory diseases: A medici..:

Pasqua, Elisa ; Hamblin, Nicole ; Edwards, Christine..
Drug Discovery Today.  27 (2022)  1 - p. 134-150 , 2022
Link: https://doi.org/10.1016/..
 
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2

Discovery of GSK251: A Highly Potent, Highly Selective, Ora..:

Down, Kenneth ; Amour, Augustin ; Anderson, Niall A....
Journal of Medicinal Chemistry.  64 (2021)  18 - p. 13780-13792 , 2021
Link: https://doi.org/10.1021/..
 
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3

An Inhaled PI3Kδ Inhibitor Improves Recovery in Acutely Exa..:

Cahn, Anthony ; Hamblin, J Nicole ; Robertson, Jon...
International Journal of Chronic Obstructive Pulmonary Disease.  16 (2021)  - p. 1607-1619 , 2021
Link: https://doi.org/10.2147/..
 
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4

Exploring PI3Kδ Molecular Pathways in Stable COPD and Follo..:

Begg, Malcolm ; Hamblin, J Nicole ; Jarvis, Emily...
International Journal of Chronic Obstructive Pulmonary Disease.  16 (2021)  - p. 1621-1636 , 2021
Link: https://doi.org/10.2147/..
 
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5

Leveraging an Open Science Drug Discovery Model to Develop ..:

Smil, David ; Wong, Jong Fu ; Williams, Eleanor P....
Journal of Medicinal Chemistry.  63 (2020)  17 - p. 10061-10085 , 2020
Link: https://doi.org/10.1021/..
 
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6

Optimization of Orally Bioavailable PI3Kδ Inhibitors and Id..:

Henley, Zoë A. ; Amour, Augustin ; Barton, Nick...
Journal of Medicinal Chemistry.  63 (2019)  2 - p. 638-655 , 2019
Link: https://doi.org/10.1021/..
 
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7

Safety, Tolerability, and Pharmacokinetics of Single and Re..:

Wilson, Robert ; Jarvis, Emily ; Montembault, Mickael...
Clinical Therapeutics.  40 (2018)  8 - p. 1410-1417 , 2018
Link: https://doi.org/10.1016/..
 
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8

Discovery of Potent, Efficient, and Selective Inhibitors of..:

Barton, Nick ; Convery, Máire ; Cooper, Anthony W. J....
Journal of Medicinal Chemistry.  61 (2018)  24 - p. 11061-11073 , 2018
Link: https://doi.org/10.1021/..
 
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9

PI3Kδ hyper-activation promotes development of B cells that..:

Stark, Anne-Katrien ; Chandra, Anita ; Chakraborty, Krishnendu...
Nature Communications.  9 (2018)  1 - p. , 2018
Link: https://doi.org/10.1038/..
 
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10

Optimization of Novel Indazoles as Highly Potent and Select..:

Down, Kenneth ; Amour, Augustin ; Baldwin, Ian R....
Journal of Medicinal Chemistry.  58 (2015)  18 - p. 7381-7399 , 2015
Link: https://doi.org/10.1021/..
 
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11

Targeting phosphoinositide 3‐kinase δ for the treatment of ..:

Sriskantharajah, Srividya ; Hamblin, Nicole ; Worsley, Sally...
Annals of the New York Academy of Sciences.  1280 (2013)  1 - p. 35-39 , 2013
Link: https://doi.org/10.1111/..
 
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12

Pyrazolopyridines as potent PDE4B inhibitors: 5-Heterocycle..:

Mitchell, Charlotte J. ; Ballantine, Stuart P. ; Coe, Diane M....
Bioorganic & Medicinal Chemistry Letters.  20 (2010)  19 - p. 5803-5806 , 2010
Link: https://doi.org/10.1016/..
 
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13

Pyrazolopyridines as a novel structural class of potent and..:

Hamblin, J. Nicole ; Angell, Tony D.R. ; Ballantine, Stuart P....
Bioorganic & Medicinal Chemistry Letters.  18 (2008)  14 - p. 4237-4241 , 2008
Link: https://doi.org/10.1016/..
 
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14

Factor Xa Inhibitors:  S1 Binding Interactions of a Series ..:

Chan, Chuen ; Borthwick, Alan D. ; Brown, David...
Journal of Medicinal Chemistry.  50 (2007)  7 - p. 1546-1557 , 2007
Link: https://doi.org/10.1021/..
 
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15

Design and synthesis of orally active pyrrolidin-2-one-base..:

Watson, Nigel S. ; Brown, David ; Campbell, Matthew...
Bioorganic & Medicinal Chemistry Letters.  16 (2006)  14 - p. 3784-3788 , 2006
Link: https://doi.org/10.1016/..
 
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