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Harcken, Christian
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Online (41)
Mediatypes
Articles (Online) (30)
OpenAccess-fulltext (11)
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1
Discovery of a Series of Pyrazinone RORγ Antagonists and Id..:
Harcken, Christian
;
Csengery, Johanna
;
Turner, Michael
...
ACS Medicinal Chemistry Letters. 12 (2021) 1 - p. 143-154 , 2021
Link:
https://doi.org/10.1021/..
?
2
Safety, pharmacokinetics and pharmacodynamics of BI 705564,..:
Litzenburger, Tobias
;
Steffgen, Jürgen
;
Benediktus, Ewald
...
British Journal of Clinical Pharmacology. 87 (2020) 4 - p. 1824-1838 , 2020
Link:
https://doi.org/10.1111/..
?
3
Identification of novel azaindazole CCR1 antagonist clinica..:
Harcken, Christian
;
Kuzmich, Daniel
;
Cook, Brain
...
Bioorganic & Medicinal Chemistry Letters. 29 (2019) 3 - p. 441-448 , 2019
Link:
https://doi.org/10.1016/..
?
4
RORγt inhibition selectively targets IL-17 producing iNKT a..:
Venken, Koen
;
Jacques, Peggy
;
Mortier, Céline
...
Nature Communications. 10 (2019) 1 - p. , 2019
Link:
https://doi.org/10.1038/..
?
5
Discovery and optimization of pyrazole amides as antagonist..:
Harcken, Christian
;
Sarko, Christopher
;
Mao, Can
...
Bioorganic & Medicinal Chemistry Letters. 29 (2019) 3 - p. 435-440 , 2019
Link:
https://doi.org/10.1016/..
?
6
An RORγt Oral Inhibitor Modulates IL-17 Responses in Periph..:
Bassolas-Molina, Helena
;
Raymond, Ernest
;
Labadia, Mark
...
Frontiers in Immunology. 9 (2018) - p. , 2018
Link:
https://doi.org/10.3389/..
?
7
BTK inhibition ameliorates kidney disease in spontaneous lu..:
Chalmers, Samantha A.
;
Glynn, Elizabeth
;
Garcia, Sayra J.
...
Clinical Immunology. 197 (2018) - p. 205-218 , 2018
Link:
https://doi.org/10.1016/..
?
8
Selective glucocorticoid receptor modulation inhibits cytok..:
Bartko, Johann
;
Derhaschnig, Ulla
;
Neels, Tania
...
Pharmacological Research. 125 (2017) - p. 215-223 , 2017
Link:
https://doi.org/10.1016/..
?
9
Therapeutic Blockade of Immune Complex-Mediated Glomerulone..:
Chalmers, Samantha A.
;
Doerner, Jessica
;
Bosanac, Todd
...
Scientific Reports. 6 (2016) 1 - p. , 2016
Link:
https://doi.org/10.1038/..
?
10
Late-stage optimization of a tercyclic class of S1P 3 -spar..:
Horan, Joshua C.
;
Kuzmich, Daniel
;
Liu, Pingrong
...
Bioorganic & Medicinal Chemistry Letters. 26 (2016) 2 - p. 466-471 , 2016
Link:
https://doi.org/10.1016/..
?
11
CCR1 Plays a Critical Role in Modulating Pain through Hemat..:
Lewis, Nuruddeen D.
;
Muthukumarana, Akalushi
;
Fogal, Steven E.
...
PLoS ONE. 9 (2014) 8 - p. e105883 , 2014
Link:
https://doi.org/10.1371/..
?
12
Discovery of a potent and dissociated non-steroidal glucoco..:
Razavi, Hossein
;
Riether, Doris
;
Harcken, Christian
...
Bioorganic & Medicinal Chemistry Letters. 24 (2014) 8 - p. 1934-1940 , 2014
Link:
https://doi.org/10.1016/..
?
13
Identification of Highly Efficacious Glucocorticoid Recepto..:
Harcken, Christian
;
Riether, Doris
;
Kuzmich, Daniel
...
Journal of Medicinal Chemistry. 57 (2014) 4 - p. 1583-1598 , 2014
Link:
https://doi.org/10.1021/..
?
14
A GPBAR1 (TGR5) Small Molecule Agonist Shows Specific Inhib..:
Lewis, Nuruddeen D.
;
Patnaude, Lori A.
;
Pelletier, Josephine
...
PLoS ONE. 9 (2014) 6 - p. e100883 , 2014
Link:
https://doi.org/10.1371/..
?
15
Development of an Enantioselective Hydrogenation Route to (..:
Reeves, Jonathan T.
;
Tan, Zhulin
;
Reeves, Diana C.
...
Organic Process Research & Development. 18 (2014) 7 - p. 904-911 , 2014
Link:
https://doi.org/10.1021/..
1-15