E-LIB Suche - Ergebnisse für: Hartley, Dylan P.

1

Identification of the Clinical Candidate PF-07284890 (ARRY-..:

Ren, Li ; Moreno, David ; Baer, Brian R....
Journal of Medicinal Chemistry. 67 (2024) 15 - p. 13019-13032 , 2024

Link: https://doi.org/10.1021/..

2

A next-generation BRAF inhibitor overcomes resistance to BR..:

Yaeger, Rona ; McKean, Meredith A. ; Haq, Rizwan...
Cancer Discovery. , 2024

Link: https://doi.org/10.1158/..

3

Discovery of Pyrazolopyrazines as Selective, Potent, and Mu..:

Bumpers, Quinn A. ; Pipal, Robert W. ; Benz-Weeden, Anna M....
Journal of Medicinal Chemistry. , 2024

Link: https://doi.org/10.1021/..

4

Discovery of Potent and Selective Covalent Inhibitors of HE..:

Hicken, Erik J. ; Brown, Karin ; Dwulet, Natalie C....
Journal of Medicinal Chemistry. 67 (2024) 11 - p. 9759-9771 , 2024

Link: https://doi.org/10.1021/..

5

SHP2 Inhibition Sensitizes Diverse Oncogene-Addicted Solid ..:

Drilon, Alexander ; Sharma, Manish R. ; Johnson, Melissa L....
Cancer Discovery. 13 (2023) 8 - p. 1789-1801 , 2023

Link: https://doi.org/10.1158/..

6

Identification of the Clinical Development Candidate MRTX84..:

Fell, Jay B. ; Fischer, John P. ; Baer, Brian R....
Journal of Medicinal Chemistry. 63 (2020) 13 - p. 6679-6693 , 2020

Link: https://doi.org/10.1021/..

7

Therapeutic Antibody-Induced Vascular Toxicity Due to Off-T..:

Pai, Rama ; Ma, Ning ; Connor, Anu V....
Toxicological Sciences. 151 (2016) 2 - p. 245-260 , 2016

Link: https://doi.org/10.1093/..

8

Pharmacokinetic drivers of toxicity for basic molecules: St..:

Diaz, Dolores ; Ford, Kevin A. ; Hartley, Dylan P....
Toxicology and Applied Pharmacology. 266 (2013) 1 - p. 86-94 , 2013

Link: https://doi.org/10.1016/..

9

Characterization of Rat Liver Proteins Adducted by Reactive..:

Khojasteh, S. Cyrus ; Hartley, Dylan P. ; Ford, Kevin A....
Chemical Research in Toxicology. 25 (2012) 11 - p. 2301-2309 , 2012

Link: https://doi.org/10.1021/..

10

Simultaneous assessment of cytochrome P450 activity in cult..:

Rhodes, Susan P. ; Otten, Jennifer N. ; Hingorani, Gary P...
Journal of Pharmacological and Toxicological Methods. 63 (2011) 3 - p. 223-226 , 2011

Link: https://doi.org/10.1016/..

11

Phosphorous Dysregulation Induced by MEK Small Molecule Inh..:

Diaz, Dolores ; Allamneni, Krishna ; Tarrant, Jacqueline M....
Toxicological Sciences. 125 (2011) 1 - p. 187-195 , 2011

Link: https://doi.org/10.1093/..

12

Identification of pregnane-X receptor target genes and coac..:

Hariparsad, Niresh ; Chu, Xiaoyan ; Yabut, Jocelyn...
Nucleic Acids Research. 37 (2009) 4 - p. 1160-1173 , 2009

Link: https://doi.org/10.1093/..

13

Identification of potential pharmacological and toxicologic..:

Hartley, Dylan P. ; Dai, Xudong ; Yabut, Jocelyn...
Pharmacogenetics and Genomics. 16 (2006) 8 - p. 579-599 , 2006

Link: https://doi.org/10.1097/..

14

Cyproterone acetate induces a cellular tolerance to cadmium..:

Takiguchi, Masufumi ; Cherrington, Nathan J. ; Hartley, Dylan P...
Toxicology. 165 (2001) 1 - p. 13-25 , 2001

Link: https://doi.org/10.1016/..

15

4-Hydroxynonenal and Malondialdehyde Hepatic Protein Adduct..:

Hartley, Dylan P. ; Kolaja, Kyle L. ; Reichard, John.
Toxicology and Applied Pharmacology. 161 (1999) 1 - p. 23-33 , 1999

Link: https://doi.org/10.1006/..