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Hartman, James J.
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1

Cardiac Troponin Activator CK-963 Increases Cardiac Contrac..:

Collibee, Scott E. ; Romero, Antonio ; Muci, Alexander R....
Journal of Medicinal Chemistry.  67 (2024)  10 - p. 7859-7869 , 2024
Link: https://doi.org/10.1021/..
 
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2

Discovery of Nelutroctiv (CK-136), a Selective Cardiac Trop..:

Romero, Antonio ; Ashcraft, Luke ; Chandra, Aroop...
Journal of Medicinal Chemistry.  67 (2024)  10 - p. 7825-7835 , 2024
Link: https://doi.org/10.1021/..
 
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3

The small-molecule troponin activator CK-136 increases myoc..:

Jani, Vivek P. ; Ma, Weikang ; Hartman, James J...
Biophysical Journal.  123 (2024)  3 - p. 402a , 2024
Link: https://doi.org/10.1016/..
 
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4

Titin-truncating variants in hiPSC cardiomyocytes induce pa..:

Huang, Guanyi ; Bisaria, Anjali ; Wakefield, Devin L....
Stem Cell Reports.  18 (2023)  1 - p. 220-236 , 2023
Link: https://doi.org/10.1016/..
 
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5

Preclinical characterization of CK-4021586, a new class of ..:

Sankar Sarkar, Saswata ; Hartman, James J. ; Hwee, Darren T....
Biophysical Journal.  122 (2023)  3 - p. 122a , 2023
Link: https://doi.org/10.1016/..
 
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6

Structural and Thermodynamic Model for the Activation of Ca..:

Poppe, Leszek ; Hartman, James J. ; Romero, Antonio.
Biochemistry.  61 (2022)  8 - p. 741-748 , 2022
Link: https://doi.org/10.1021/..
 
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7

Novel Small-Molecule Troponin Activator Increases Cardiac C..:

He, Huamei ; Baka, Tomas ; Balschi, James...
Circulation: Heart Failure.  15 (2022)  3 - p. , 2022
Link: https://doi.org/10.1161/..
 
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8

Distinct Mechanisms for Increased Cardiac Contraction Throu..:

Singh, Rohit R. ; Slater, Rebecca E. ; Wang, Jinghong...
JACC: Basic to Translational Science.  7 (2022)  10 - p. 1021-1037 , 2022
Link: https://doi.org/10.1016/..
 
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9

Discovery of Aficamten (CK-274), a Next-Generation Cardiac ..:

Chuang, Chihyuan ; Collibee, Scott ; Ashcraft, Luke...
Journal of Medicinal Chemistry.  64 (2021)  19 - p. 14142-14152 , 2021
Link: https://doi.org/10.1021/..
 
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10

Discovery of Reldesemtiv, a Fast Skeletal Muscle Troponin A..:

Collibee, Scott E. ; Bergnes, Gustave ; Chuang, Chihyuan...
Journal of Medicinal Chemistry.  64 (2021)  20 - p. 14930-14941 , 2021
Link: https://doi.org/10.1021/..
 
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11

Structural Basis of Tirasemtiv Activation of Fast Skeletal ..:

Li, Monica X. ; Mercier, Pascal ; Hartman, James J..
Journal of Medicinal Chemistry.  64 (2021)  6 - p. 3026-3034 , 2021
Link: https://doi.org/10.1021/..
 
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12

Discovery of Tirasemtiv, the First Direct Fast Skeletal Mus..:

Collibee, Scott E. ; Bergnes, Gustave ; Muci, Alexander...
ACS Medicinal Chemistry Letters.  9 (2018)  4 - p. 354-358 , 2018
Link: https://doi.org/10.1021/..
 
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13

Supraphysiological levels ofGDF11 induce striated muscle at..:

Hammers, David W ; Merscham‐Banda, Melissa ; Hsiao, Jennifer Ying...
EMBO Molecular Medicine.  9 (2017)  4 - p. 531-544 , 2017
Link: https://doi.org/10.15252..
 
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14

Preconception exposure to dietary levels of genistein affec..:

Patel, Shreya ; Hartman, James A. ; Helferich, William G..
Reproductive Toxicology.  74 (2017)  - p. 174-180 , 2017
Link: https://doi.org/10.1016/..
 
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15

Mechanistic and structural basis for activation of cardiac ..:

Planelles-Herrero, Vicente J. ; Hartman, James J. ; Robert-Paganin, Julien..
Nature Communications.  8 (2017)  1 - p. , 2017
Link: https://doi.org/10.1038/..
 
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