E-LIB Suche - Ergebnisse für: Hennessy, Edward J.

1

Discovery and Optimization of the First ATP Competitive Typ..:

Michaelides, Iacovos N. ; Collie, Gavin W. ; Börjesson, Ulf...
Journal of Medicinal Chemistry. 66 (2023) 13 - p. 8782-8807 , 2023

Link: https://doi.org/10.1021/..

2

Design and optimisation of dendrimer-conjugated Bcl-2/xL in..:

Patterson, Claire M. ; Balachander, Srividya B. ; Grant, Iain...
Communications Biology. 4 (2021) 1 - p. , 2021

Link: https://doi.org/10.1038/..

3

Optimization of an Imidazo[1,2-a]pyridine Series to Afford ..:

McCoull, William ; Boyd, Scott ; Brown, Martin R....
Journal of Medicinal Chemistry. 64 (2021) 18 - p. 13524-13539 , 2021

Link: https://doi.org/10.1021/..

4

Generating Selective Leads for Mer Kinase Inhibitors—Exampl..:

Nissink, J. Willem M. ; Bazzaz, Sana ; Blackett, Carolyn...
Journal of Medicinal Chemistry. 64 (2021) 6 - p. 3165-3184 , 2021

Link: https://doi.org/10.1021/..

5

Structural and Molecular Insight into Resistance Mechanisms..:

Collie, Gavin W. ; Koh, Cheryl M. ; O'Neill, Daniel J....
ACS Medicinal Chemistry Letters. 10 (2019) 9 - p. 1322-1327 , 2019

Link: https://doi.org/10.1021/..

6

Preparation of highly functionalized 1,5-disubstituted tetr..:

Hennessy, Edward J. ; Cornebise, Mark ; Gingipalli, Lakshmaiah...
Tetrahedron Letters. 58 (2017) 17 - p. 1709-1713 , 2017

Link: https://doi.org/10.1016/..

7

Utilization of Structure-Based Design to Identify Novel, Ir..:

Hennessy, Edward J. ; Chuaqui, Claudio ; Ashton, Susan...
ACS Medicinal Chemistry Letters. 7 (2016) 5 - p. 514-519 , 2016

Link: https://doi.org/10.1021/..

8

Optimization of Highly Kinase Selective Bis-anilino Pyrimid..:

McCoull, William ; Hennessy, Edward J. ; Blades, Kevin...
ACS Medicinal Chemistry Letters. 7 (2016) 12 - p. 1118-1123 , 2016

Link: https://doi.org/10.1021/..

9

Selective inhibitors of Bcl-2 and Bcl-xL: Balancing antitum..:

Hennessy, Edward J.
Bioorganic & Medicinal Chemistry Letters. 26 (2016) 9 - p. 2105-2114 , 2016

Link: https://doi.org/10.1016/..

10

Identification and Optimization of Benzimidazole Sulfonamid..:

Hennessy, Edward J. ; Oza, Vibha ; Adam, Ammar...
Journal of Medicinal Chemistry. 58 (2015) 17 - p. 7057-7075 , 2015

Link: https://doi.org/10.1021/..

11

Discovery of heterocyclic sulfonamides as sphingosine 1-pho..:

Hennessy, Edward J. ; Grewal, Gurmit ; Byth, Kate...
Bioorganic & Medicinal Chemistry Letters. 25 (2015) 10 - p. 2041-2045 , 2015

Link: https://doi.org/10.1016/..

12

Identification and optimisation of 7-azaindole PAK1 inhibit..:

McCoull, William ; Hennessy, Edward J. ; Blades, Kevin...
Med. Chem. Commun.. 5 (2014) 10 - p. 1533-1539 , 2014

Link: https://doi.org/10.1039/..

13

Discovery of Potent KIFC1 Inhibitors Using a Method of Inte..:

Yang, Bin ; Lamb, Michelle L. ; Zhang, Tao...
Journal of Medicinal Chemistry. 57 (2014) 23 - p. 9958-9970 , 2014

Link: https://doi.org/10.1021/..

14

Structure-based design and synthesis of tricyclic IAP (Inhi..:

Hird, Alexander W. ; Aquila, Brian M. ; Block, Michael H....
Bioorganic & Medicinal Chemistry Letters. 24 (2014) 7 - p. 1820-1824 , 2014

Link: https://doi.org/10.1016/..

15

Discovery of a Novel Class of Dimeric Smac Mimetics as Pote..:

Hennessy, Edward J. ; Adam, Ammar ; Aquila, Brian M....
Journal of Medicinal Chemistry. 56 (2013) 24 - p. 9897-9919 , 2013

Link: https://doi.org/10.1021/..