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Hie, Brian
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1

Large language models for science and medicine:

Telenti, Amalio ; Auli, Michael ; Hie, Brian L....
European Journal of Clinical Investigation.  54 (2024)  6 - p. , 2024
Link: https://doi.org/10.1111/..
 
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2

Scanorama: integrating large and diverse single-cell transc..:

Hie, Brian L. ; Kim, Soochi ; Rando, Thomas A...
Nature Protocols.  , 2024
Link: https://doi.org/10.1038/..
 
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3

Unsupervised evolution of protein and antibody complexes wi..:

Shanker, Varun R. ; Bruun, Theodora U. J. ; Hie, Brian L..
Science.  385 (2024)  6704 - p. 46-53 , 2024
Link: https://doi.org/10.1126/..
 
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4

Generative artificial intelligence for de novo protein desi..:

Winnifrith, Adam ; Outeiral, Carlos ; Hie, Brian L.
Current Opinion in Structural Biology.  86 (2024)  - p. 102794 , 2024
Link: https://doi.org/10.1016/..
 
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5

Machine Learning for Protein Engineering:

, In: Challenges and Advances in Computational Chemistry and Physics; Machine Learning in Molecular Sciences,
Johnston, Kadina E. ; Fannjiang, Clara ; Wittmann, Bruce J.... - p. 277-311 , 2023
Link: https://doi.org/10.1007/..
 
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6

Efficient evolution of human antibodies from general protei..:

Hie, Brian L. ; Shanker, Varun R. ; Xu, Duo...
Nature Biotechnology.  42 (2023)  2 - p. 275-283 , 2023
Link: https://doi.org/10.1038/..
 
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7

Evolutionary-scale prediction of atomic-level protein struc..:

Lin, Zeming ; Akin, Halil ; Rao, Roshan...
Science.  379 (2023)  6637 - p. 1123-1130 , 2023
Link: https://doi.org/10.1126/..
 
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8

Adaptive machine learning for protein engineering:

Hie, Brian L. ; Yang, Kevin K.
Current Opinion in Structural Biology.  72 (2022)  - p. 145-152 , 2022
Link: https://doi.org/10.1016/..
 
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9

Evolutionary velocity with protein language models predicts..:

Hie, Brian L. ; Yang, Kevin K. ; Kim, Peter S.
Cell Systems.  13 (2022)  4 - p. 274-285.e6 , 2022
Link: https://doi.org/10.1016/..
 
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10

Learning the language of viral evolution and escape:

Hie, Brian ; Zhong, Ellen D. ; Berger, Bonnie.
Science.  371 (2021)  6526 - p. 284-288 , 2021
Link: https://doi.org/10.1126/..
 
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11

Schema: metric learning enables interpretable synthesis of ..:

Singh, Rohit ; Hie, Brian L. ; Narayan, Ashwin.
Genome Biology.  22 (2021)  1 - p. , 2021
Link: https://doi.org/10.1186/..
 
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12

Leveraging Uncertainty in Machine Learning Accelerates Biol..:

Hie, Brian ; Bryson, Bryan D. ; Berger, Bonnie
Cell Systems.  11 (2020)  5 - p. 461-477.e9 , 2020
Link: https://doi.org/10.1016/..
 
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13

Fine-mapping cis-regulatory variants in diverse human popul..:

Tehranchi, Ashley ; Hie, Brian ; Dacre, Michael...
eLife.  8 (2019)  - p. , 2019
Link: https://doi.org/10.7554/..
 
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14

Efficient integration of heterogeneous single-cell transcri..:

Hie, Brian ; Bryson, Bryan ; Berger, Bonnie
Nature Biotechnology.  37 (2019)  6 - p. 685-691 , 2019
Link: https://doi.org/10.1038/..
 
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15

Realizing private and practical pharmacological collaborati..:

Hie, Brian ; Cho, Hyunghoon ; Berger, Bonnie
Science.  362 (2018)  6412 - p. 347-350 , 2018
Link: https://doi.org/10.1126/..
 
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