E-LIB Suche - Ergebnisse für: Hirst, David J

1

Structure- and Property-Based Optimization of Efficient Pan..:

Hirst, David J. ; Bamborough, Paul ; Al-Mahdi, Niam...
Journal of Medicinal Chemistry. 67 (2024) 12 - p. 10464-10489 , 2024

Link: https://doi.org/10.1021/..

2

In skeletal muscle and neural crest cells, SMCHD1 regulates..:

Laberthonnière, Camille ; Delourme, Mégane ; Chevalier, Raphaël...
Nucleic Acids Research. 51 (2023) 14 - p. 7269-7287 , 2023

Link: https://doi.org/10.1093/..

3

In situ silane activation enables catalytic reduction of ca..:

Stoll, Emma L. ; Barber, Thomas ; Hirst, David J..
Chemical Communications. 58 (2022) 21 - p. 3509-3512 , 2022

Link: https://doi.org/10.1039/..

4

Design, Synthesis, and Characterization of I-BET567, a Pan-..:

Humphreys, Philip G. ; Atkinson, Stephen J. ; Bamborough, Paul...
Journal of Medicinal Chemistry. 65 (2022) 3 - p. 2262-2287 , 2022

Link: https://doi.org/10.1021/..

5

Identification and Optimization of a Ligand-Efficient Benzo..:

Humphreys, Philip G. ; Anderson, Niall A. ; Bamborough, Paul...
Journal of Medicinal Chemistry. 65 (2022) 22 - p. 15174-15207 , 2022

Link: https://doi.org/10.1021/..

6

GSK137, a potent small-molecule BCL6 inhibitor with in vivo..:

Pearce, Andrew C. ; Bamford, Mark J. ; Barber, Ruth...
Journal of Biological Chemistry. 297 (2021) 2 - p. 100928 , 2021

Link: https://doi.org/10.1016/..

7

A Turing Test for Molecular Generators:

Bush, Jacob T. ; Pogany, Peter ; Pickett, Stephen D....
Journal of Medicinal Chemistry. 63 (2020) 20 - p. 11964-11971 , 2020

Link: https://doi.org/10.1021/..

8

Hydrogen Atom Transfer‐Mediated Domino Cyclisation Reaction..:

Turner, Oliver J. ; Hirst, David J. ; Murphy, John A.
Chemistry – A European Journal. 26 (2020) 14 - p. 3026-3029 , 2020

Link: https://doi.org/10.1002/..

9

Discovery of a Bromodomain and Extraterminal Inhibitor with..:

Wellaway, Christopher R. ; Amans, Dominique ; Bamborough, Paul...
Journal of Medicinal Chemistry. 63 (2020) 2 - p. 714-746 , 2020

Link: https://doi.org/10.1021/..

10

Structure-based optimisation of orally active & reversible ..:

Hirst, David J. ; Brandt, Martin ; Bruton, Gordon...
Bioorganic & Medicinal Chemistry Letters. 30 (2020) 21 - p. 127533 , 2020

Link: https://doi.org/10.1016/..

11

A practical catalytic reductive amination of carboxylic aci..:

Stoll, Emma L. ; Tongue, Thomas ; Andrews, Keith G....
Chemical Science. 11 (2020) 35 - p. 9494-9500 , 2020

Link: https://doi.org/10.1039/..

12

Characterization of P. falciparum dipeptidyl aminopeptidase..:

de Vries, Laura E. ; Sanchez, Mateo I. ; Groborz, Katarzyna...
The FEBS Journal. 286 (2019) 20 - p. 3998-4023 , 2019

Link: https://doi.org/10.1111/..

13

Discovery of Tetrahydroquinoxalines as Bromodomain and Extr..:

Law, Robert P. ; Atkinson, Stephen J. ; Bamborough, Paul...
Journal of Medicinal Chemistry. 61 (2018) 10 - p. 4317-4334 , 2018

Link: https://doi.org/10.1021/..

14

Atom Efficient Synthesis of Selectively Difluorinated Carbo..:

McCarter, Adam W. ; Sommer, Magdalena ; Percy, Jonathan M....
The Journal of Organic Chemistry. 83 (2018) 16 - p. 8888-8905 , 2018

Link: https://doi.org/10.1021/..

15

Hydrogen Atom Transfer‐Mediated Cyclisations of Nitriles:

Turner, Oliver J. ; Murphy, John A. ; Hirst, David J..
Chemistry – A European Journal. 24 (2018) 70 - p. 18658-18662 , 2018

Link: https://doi.org/10.1002/..