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Hockla, Alexandra
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1

Abstract 1734 Investigating the catalytic activity of PRSS2..:

Akhtar, Sharoon ; Ilic, Stefan ; Coban, Matt...
Journal of Biological Chemistry.  300 (2024)  3 - p. 106189 , 2024
Link: https://doi.org/10.1016/..
 
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2

Abstract 1331 Engineering Tissue Inhibitor of Metalloprotei..:

Shoari, Alireza ; Hockla, Alexandra ; Coban, Matt.
Journal of Biological Chemistry.  300 (2024)  3 - p. 106870 , 2024
Link: https://doi.org/10.1016/..
 
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3

Designed Loop Extension Followed by Combinatorial Screening..:

Bonadio, Alessandro ; Wenig, Bernhard L. ; Hockla, Alexandra..
Journal of Molecular Biology.  435 (2023)  13 - p. 168095 , 2023
Link: https://doi.org/10.1016/..
 
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4

Engineering of tissue inhibitor of metalloproteinases TIMP-..:

Raeeszadeh-Sarmazdeh, Maryam ; Coban, Mathew ; Mahajan, Shivansh...
Journal of Biological Chemistry.  298 (2022)  3 - p. 101654 , 2022
Link: https://doi.org/10.1016/..
 
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5

Activity-based protein profiling reveals active serine prot..:

Mehner, Christine ; Hockla, Alexandra ; Coban, Mathew...
Journal of Biological Chemistry.  298 (2022)  8 - p. 102146 , 2022
Link: https://doi.org/10.1016/..
 
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6

MMP1 drives tumor progression in large cell carcinoma of th..:

Gabasa, Marta ; Radisky, Evette S. ; Ikemori, Rafael...
Cancer Letters.  507 (2021)  - p. 1-12 , 2021
Link: https://doi.org/10.1016/..
 
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7

Targeting an autocrine IL-6–SPINK1 signaling axis to suppre..:

Mehner, Christine ; Miller, Erin ; Hockla, Alexandra...
Oncogene.  39 (2020)  42 - p. 6606-6618 , 2020
Link: https://doi.org/10.1038/..
 
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8

Structural Basis for Improved Proteolytic Stability and Tar..:

Coban, Matt ; Cohen, Itay ; Shahar, Anat...
The FASEB Journal.  33 (2019)  S1 - p. , 2019
Link: https://doi.org/10.1096/..
 
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9

PRSS3/Mesotrypsin and kallikrein-related peptidase 5 are as..:

Ma, Honghai ; Hockla, Alexandra ; Mehner, Christine...
Scientific Reports.  9 (2019)  1 - p. , 2019
Link: https://doi.org/10.1038/..
 
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10

Disulfide engineering of human Kunitz-type serine protease ..:

Cohen, Itay ; Coban, Matt ; Shahar, Anat...
Journal of Biological Chemistry.  294 (2019)  13 - p. 5105-5120 , 2019
Link: https://doi.org/10.1074/..
 
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11

A potent, proteolysis-resistant inhibitor of kallikrein-rel..:

Sananes, Amiram ; Cohen, Itay ; Shahar, Anat...
Journal of Biological Chemistry.  293 (2018)  33 - p. 12663-12680 , 2018
Link: https://doi.org/10.1074/..
 
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12

Mapping protein selectivity landscapes using multi-target s..:

Naftaly, Si ; Cohen, Itay ; Shahar, Anat...
Nature Communications.  9 (2018)  1 - p. , 2018
Link: https://doi.org/10.1038/..
 
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13

Identifying a serine protease network involved in ovarian c..:

Mehner, Christine ; Hockla, Alexandra ; Radisky, Derek C.
The FASEB Journal.  31 (2017)  S1 - p. , 2017
Link: https://doi.org/10.1096/..
 
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14

An Acrobatic Substrate Metamorphosis Reveals a Requirement ..:

Kayode, Olumide ; Wang, Ruiying ; Pendlebury, Devon F....
Journal of Biological Chemistry.  291 (2016)  51 - p. 26304-26319 , 2016
Link: https://doi.org/10.1074/..
 
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15

Serine protease inhibitor Kazal type 1 (SPINK1) drives prol..:

Mehner, Christine ; Oberg, Ann L. ; Kalli, Kimberly R....
Oncotarget.  6 (2015)  34 - p. 35737-35754 , 2015
Link: https://doi.org/10.18632..
 
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