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Holenz, Jörg
31  results:
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1

Toward β-Secretase-1 Inhibitors with Improved Isoform Selec..:

Johansson, Patrik ; Kaspersson, Karin ; Gurrell, Ian K....
Journal of Medicinal Chemistry.  61 (2018)  8 - p. 3491-3502 , 2018
Link: https://doi.org/10.1021/..
 
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2

Lead generation: methods, strategies, and case studies 

Methods and Principles in Medicinal Chemistry
Holenz, Jörg , 2016
Link: https://onlinelibrary.wi..
 
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3

Sulfonimidamides as Sulfonamides Bioisosteres: Rational Eva..:

Sehgelmeble, Fernando ; Janson, Juliette ; Ray, Colin...
ChemMedChem.  7 (2012)  3 - p. 396-399 , 2012
Link: https://doi.org/10.1002/..
 
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4

Aminoimidazoles as BACE-1 inhibitors: The challenge to achi..:

Swahn, Britt-Marie ; Holenz, Jörg ; Kihlström, Jacob...
Bioorganic & Medicinal Chemistry Letters.  22 (2012)  5 - p. 1854-1859 , 2012
Link: https://doi.org/10.1016/..
 
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5

Thiophene Bioisosteres of Spirocyclic σ Receptor Ligands: R..:

Oberdorf, Christoph ; Schepmann, Dirk ; Vela, Jose Miguel...
Journal of Medicinal Chemistry.  55 (2012)  11 - p. 5350-5360 , 2012
Link: https://doi.org/10.1021/..
 
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6

Microwave assisted synthesis of spirocyclic pyrrolidines – ..:

Jasper, Annemarie ; Schepmann, Dirk ; Lehmkuhl, Kirstin...
European Journal of Medicinal Chemistry.  53 (2012)  - p. 327-336 , 2012
Link: https://doi.org/10.1016/..
 
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7

Synthesis and Biological Evaluation of the 1-Arylpyrazole C..:

Díaz, José Luis ; Cuberes, Rosa ; Berrocal, Joana...
Journal of Medicinal Chemistry.  55 (2012)  19 - p. 8211-8224 , 2012
Link: https://doi.org/10.1021/..
 
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8

Design and Synthesis of β-Site Amyloid Precursor Protein Cl..:

Swahn, Britt-Marie ; Kolmodin, Karin ; Karlström, Sofia...
Journal of Medicinal Chemistry.  55 (2012)  21 - p. 9346-9361 , 2012
Link: https://doi.org/10.1021/..
 
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9

Combination of Two Pharmacophoric Systems: Synthesis and Ph..:

Schläger, Torsten ; Schepmann, Dirk ; Lehmkuhl, Kirstin...
Journal of Medicinal Chemistry.  54 (2011)  19 - p. 6704-6713 , 2011
Link: https://doi.org/10.1021/..
 
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10

Synthesis and Pharmacological Evaluation of a Potent and Se..:

Utech, Tina ; Köhler, Jens ; Buschmann, Helmut...
Archiv der Pharmazie.  344 (2011)  7 - p. 415-421 , 2011
Link: https://doi.org/10.1002/..
 
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11

Pharmacological and metabolic characterisation of the poten..:

Wiese, Christian ; Maestrup, Eva Große ; Schepmann, Dirk...
Journal of Pharmacy and Pharmacology.  61 (2010)  5 - p. 631-640 , 2010
Link: https://doi.org/10.1211/..
 
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12

Synthesis of σ receptor ligands with unsymmetrical spiro co..:

Jasper, Annemarie ; Schepmann, Dirk ; Lehmkuhl, Kirstin...
European Journal of Medicinal Chemistry.  44 (2009)  11 - p. 4306-4314 , 2009
Link: https://doi.org/10.1016/..
 
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13

Pharmacological and metabolic characterisation of the poten..:

Wiese, Christian ; Maestrup, Eva Große ; Schepmann, Dirk...
Journal of Pharmacy and Pharmacology.  61 (2009)  5 - p. 631-640 , 2009
Link: https://doi.org/10.1211/..
 
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14

Identification of Novel Indanylsulfonamide Guanylhydrazones..:

Mesquida, Neus ; López-Pérez, Sara ; Dinarès, Immaculada...
Journal of Medicinal Chemistry.  52 (2009)  19 - p. 6153-6157 , 2009
Link: https://doi.org/10.1021/..
 
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15

Indene-based frameworks targeting the 5-HT6 serotonin recep..:

Alcalde, Ermitas ; Mesquida, Neus ; López-Pérez, Sara...
Bioorganic & Medicinal Chemistry.  17 (2009)  20 - p. 7387-7397 , 2009
Link: https://doi.org/10.1016/..
 
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