E-LIB Suche - Ergebnisse für: Hopkins, Brian T.

1

The Discovery of 7-Isopropoxy-2-(1-methyl-2-oxabicyclo[2.1...:

Evans, Ryan ; Bolduc, Philippe N. ; Pfaffenbach, Magnus...
Journal of Medicinal Chemistry. 67 (2024) 6 - p. 4676-4690 , 2024

Link: https://doi.org/10.1021/..

2

Discovery of structural diverse reversible BTK inhibitors u..:

Vandeveer, George H. ; Arduini, Robert M. ; Baker, Darren P....
Bioorganic & Medicinal Chemistry Letters. 80 (2023) - p. 129108 , 2023

Link: https://doi.org/10.1016/..

3

Discovery of Phospholipase D Inhibitors with Improved Drug-..:

May-Dracka, Tricia L. ; Gao, Fang ; Hopkins, Brian T....
ACS Medicinal Chemistry Letters. 13 (2022) 4 - p. 665-673 , 2022

Link: https://doi.org/10.1021/..

4

Optimization of a novel piperazinone series as potent selec..:

Ma, Bin ; Metrick, Claire M. ; Gu, Chungang...
Bioorganic & Medicinal Chemistry Letters. 60 (2022) - p. 128549 , 2022

Link: https://doi.org/10.1016/..

5

Corrigendum to "Optimization of a novel piperazinone series..:

Ma, Bin ; Metrick, Claire M. ; Gu, Chungang...
Bioorganic & Medicinal Chemistry Letters. 72 (2022) - p. 128856 , 2022

Link: https://doi.org/10.1016/..

6

BTK inhibition limits B-cell–T-cell interaction through mod..:

Li, Rui ; Tang, Hao ; Burns, Jeremy C....
Acta Neuropathologica. 143 (2022) 4 - p. 505-521 , 2022

Link: https://doi.org/10.1007/..

7

Sulfone Displacement Approach for Large-Scale Synthesis of ..:

Li, Chaomin ; Haeffner, Fredrik ; Wang, Shujun...
Organic Process Research & Development. 26 (2021) 1 - p. 137-143 , 2021

Link: https://doi.org/10.1021/..

8

Utilizing structure based drug design and metabolic soft sp..:

Hopkins, Brian T. ; Bame, Eris ; Bell, Noah...
Bioorganic & Medicinal Chemistry. 44 (2021) - p. 116275 , 2021

Link: https://doi.org/10.1016/..

9

Discovery and Preclinical Characterization of BIIB091, a Re..:

Hopkins, Brian T. ; Bame, Eris ; Bajrami, Bekim...
Journal of Medicinal Chemistry. 65 (2021) 2 - p. 1206-1224 , 2021

Link: https://doi.org/10.1021/..

10

Discovery of BIIB068: A Selective, Potent, Reversible Bruto..:

Ma, Bin ; Bohnert, Tonika ; Otipoby, Kevin L....
Journal of Medicinal Chemistry. 63 (2020) 21 - p. 12526-12541 , 2020

Link: https://doi.org/10.1021/..

11

Process Development and Large-Scale Synthesis of BTK Inhibi..:

Li, Chaomin ; Franklin, Lloyd ; Chen, Robbie...
Organic Process Research & Development. 24 (2020) 6 - p. 1199-1206 , 2020

Link: https://doi.org/10.1021/..

12

Utilization of Cyclic Amides as Masked Aldehyde Equivalents..:

Prince, Robin J. ; Gao, Fang ; Pazienza, Jessica E....
The Journal of Organic Chemistry. 84 (2019) 12 - p. 7936-7949 , 2019

Link: https://doi.org/10.1021/..

13

Optimization of novel reversible Bruton's tyrosine kinase i..:

Hopkins, Brian T. ; Bame, Eris ; Bell, Noah...
Bioorganic & Medicinal Chemistry. 27 (2019) 13 - p. 2905-2913 , 2019

Link: https://doi.org/10.1016/..

14

Structures of human Bruton's tyrosine kinase in active and ..:

Marcotte, Douglas J. ; Liu, Yu‐Ting ; Arduini, Robert M....
Protein Science. 19 (2010) 3 - p. 429-439 , 2010

Link: https://doi.org/10.1002/..

15

Identification of individual protein–ligand NOEs in the lim..:

Reibarkh, Mikhail ; Malia, Thomas J. ; Hopkins, Brian T..
Journal of Biomolecular NMR. 36 (2006) 1 - p. 1-11 , 2006

Link: https://doi.org/10.1007/..