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Hubbs, Jed L.
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1

ALDH5A1-deficient iPSC-derived excitatory and inhibitory ne..:

Afshar-Saber, Wardiya ; Teaney, Nicole A. ; Winden, Kellen D....
Neurobiology of Disease.  190 (2024)  - p. 106386 , 2024
Link: https://doi.org/10.1016/..
 
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2

High-content screening identifies a small molecule that res..:

Saffari, Afshin ; Brechmann, Barbara ; Böger, Cedric...
Nature Communications.  15 (2024)  1 - p. , 2024
Link: https://doi.org/10.1038/..
 
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3

Minimization of drug–drug interaction risk and candidate se..:

Hubbs, Jed L. ; Fuller, Nathan O. ; Austin, Wesley F....
Bioorganic & Medicinal Chemistry Letters.  25 (2015)  7 - p. 1621-1626 , 2015
Link: https://doi.org/10.1016/..
 
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4

Multikilogram-Scale Production of Cycloartenol Triterpenoid..:

Shen, Ruichao ; Fuller, Nathan O. ; Osswald, Gerd...
Organic Process Research & Development.  18 (2014)  6 - p. 676-682 , 2014
Link: https://doi.org/10.1021/..
 
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5

Optimization of a Kilogram-Scale Synthesis of a Potent Cycl..:

Fuller, Nathan O. ; Hubbs, Jed L. ; Austin, Wesley F....
Organic Process Research & Development.  18 (2014)  6 - p. 683-692 , 2014
Link: https://doi.org/10.1021/..
 
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6

Delayed and Prolonged Histone Hyperacetylation with a Selec..:

Methot, Joey L. ; Hoffman, Dawn Mampreian ; Witter, David J....
ACS Medicinal Chemistry Letters.  5 (2014)  4 - p. 340-345 , 2014
Link: https://doi.org/10.1021/..
 
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7

Efficacy of SPI-1865, a novel gamma-secretase modulator, in..:

Loureiro, Robyn M ; Dumin, Jo ; McKee, Timothy D...
Alzheimer's Research & Therapy.  5 (2013)  2 - p. 19 , 2013
Link: https://doi.org/10.1186/..
 
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8

SAR investigations on a novel class of gamma-secretase modu..:

Austin, Wesley F. ; Hubbs, Jed L. ; Fuller, Nathan O....
MedChemComm.  4 (2013)  3 - p. 569 , 2013
Link: https://doi.org/10.1039/..
 
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9

Initial Optimization of a New Series of γ-Secretase Modulat..:

Fuller, Nathan O. ; Hubbs, Jed L. ; Austin, Wesley F....
ACS Medicinal Chemistry Letters.  3 (2012)  11 - p. 908-913 , 2012
Link: https://doi.org/10.1021/..
 
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10

Modulation of Gamma-Secretase for the Treatment of Alzheime..:

Tate, Barbara ; McKee, Timothy D. ; Loureiro, Robyn M. B....
International Journal of Alzheimer's Disease.  2012 (2012)  - p. 1-10 , 2012
Link: https://doi.org/10.1155/..
 
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11

P4‐199: Pharmacokinetic properties of a Satori gamma‐secret..:

Bronk, Brian ; McKee, Timothy ; Loureiro, Robyn...
Alzheimer's & Dementia.  8 (2012)  4S_Part_19 - p. , 2012
Link: https://doi.org/10.1016/..
 
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12

O1‐11‐01: Satori gamma‐secretase modulators are efficacious..:

Loureiro, Robyn ; McKee, Timothy ; Dumin, Jo Ann...
Alzheimer's & Dementia.  8 (2012)  4S_Part_3 - p. , 2012
Link: https://doi.org/10.1016/..
 
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13

Optimization of a Natural Product-Based Class of γ-Secretas..:

Hubbs, Jed L. ; Fuller, Nathan O. ; Austin, Wesley F....
Journal of Medicinal Chemistry.  55 (2012)  21 - p. 9270-9282 , 2012
Link: https://doi.org/10.1021/..
 
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14

P1‐028: Gamma—secretase modulators do not show a potency sh..:

Bronk, Brian ; Tate, Barbara ; Loureiro, Robyn...
Alzheimer's & Dementia.  7 (2011)  4S_Part_3 - p. , 2011
Link: https://doi.org/10.1016/..
 
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15

P2‐513: Classification of γ‐secretase modulators and their ..:

Xia, Weiming ; McKee, Timothy ; Loureiro, Robyn...
Alzheimer's & Dementia.  7 (2011)  4S_Part_14 - p. , 2011
Link: https://doi.org/10.1016/..
 
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